Restriction-methylation systems regulate transformation in Acinetobacter baumannii.

Acinetobacter baumannii / genetics Methylation Anti-Bacterial Agents Gene Transfer, Horizontal Microbial Sensitivity Tests
Acinetobacter baumannii DNA methylation horizontal gene transfer natural competence for transformation transformation

Journal

Trends in microbiology
ISSN: 1878-4380
Titre abrégé: Trends Microbiol
Pays: England
ID NLM: 9310916

Informations de publication

Date de publication:
09 2023
Historique:
received: 07 07 2023
revised: 14 07 2023
accepted: 17 07 2023
medline: 17 8 2023
pubmed: 27 7 2023
entrez: 26 7 2023
Statut: ppublish

Résumé

Antimicrobial resistance in Acinetobacter baumannii is a major concern. Natural transformation remains understudied as a horizontal gene transfer (HGT) mechanism for the spread of resistance genes. Recent work (Vesel et al.) reveals a profound impact of the state of donor DNA methylation with strong implications for HGT of resistance determinants in this worrisome pathogen.

Identifiants

DOI: 10.1016/j.tim.2023.07.009 PMID: 37495486
pubmed: 37495486
pii: S0966-842X(23)00206-8
doi: 10.1016/j.tim.2023.07.009
pii:
doi:

Substances chimiques

Anti-Bacterial Agents 0

Types de publication

Journal Article Comment

Langues

eng

Sous-ensembles de citation

IM

Pagination

879-881

Commentaires et corrections

Type : CommentOn

Informations de copyright

Copyright © 2023 Elsevier Ltd. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of interests No interests are declared.

Auteurs

Alfonso Soler-Bistué (A)

Instituto de Investigaciones Biotecnológicas 'Dr Rodolfo A. Ugalde', IIB-IIBIO, Universidad Nacional de San Martín-CONICET, San Martín, Buenos Aires, Argentina. Electronic address: asoler@iib.unsam.edu.ar.

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Classifications MeSH

questionsmedicales.fr › Bactéries › Proteobacteria › Gammaproteobacteria › Moraxellaceae › Acinetobacter › Acinetobacter baumannii › Restriction-methylation systems regulate...
questionsmedicales.fr › Métabolisme › Alkylation › Méthylation › Restriction-methylation systems regulate...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Anti-infectieux › Antibactériens › Restriction-methylation systems regulate...
questionsmedicales.fr › Phénomènes génétiques › Recombinaison génétique › Transfert horizontal de gène › Restriction-methylation systems regulate...
questionsmedicales.fr › Techniques d'investigation › Évaluation préclinique de médicament › Tests de sensibilité microbienne › Restriction-methylation systems regulate...