Ent-eudesmane sesquiterpenoids from the Chinese liverwort Chiloscyphus polyanthus.
Antifungal activity
Chiloscyphus polyanthus var. rivularis
Cytotoxicity
Ent-eudesmane sesquiterpenoids
Liverworts
Journal
Phytochemistry
ISSN: 1873-3700
Titre abrégé: Phytochemistry
Pays: England
ID NLM: 0151434
Informations de publication
Date de publication:
Oct 2023
Oct 2023
Historique:
received:
04
04
2023
revised:
20
07
2023
accepted:
21
07
2023
medline:
4
9
2023
pubmed:
28
7
2023
entrez:
27
7
2023
Statut:
ppublish
Résumé
- Seven previously undescribed ent-eudesmane sesquiterpenoids (1-7), as well as seven known analogs (8-14), were isolated from the Chinese liverwort Chiloscyphus polyanthus var. rivularis. Their structures were established based on comprehensive spectroscopy analysis, electronic circular dichroism calculations, as well as biosynthetic considerations. The cytotoxicity against HepG2 (Human hepatocellular carcinomas) cancer cell line, and antifungal activity against Candida albicans SC5314 of all isolated ent-eudesmane sesquiterpenoids were preliminarily tested, results showed that the tested compounds did not display obvious cytotoxicity and antifungal activities under the tested concentration.
Identifiants
pubmed: 37499849
pii: S0031-9422(23)00212-1
doi: 10.1016/j.phytochem.2023.113796
pii:
doi:
Substances chimiques
Antifungal Agents
0
eudesmane
473-11-0
Sesquiterpenes
0
Sesquiterpenes, Eudesmane
0
Antineoplastic Agents
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
113796Informations de copyright
Copyright © 2023 Elsevier Ltd. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.