Eosinophilic Myenteric Ganglionitis Presenting as Sigmoid Volvulus: A Brief Report.


Journal

The American surgeon
ISSN: 1555-9823
Titre abrégé: Am Surg
Pays: United States
ID NLM: 0370522

Informations de publication

Date de publication:
Nov 2023
Historique:
medline: 6 12 2023
pubmed: 28 7 2023
entrez: 28 7 2023
Statut: ppublish

Résumé

Eosinophilic myenteric ganglionitis (EMG) is a rare pathologic finding within the Auerbach myenteric plexus characterized by eosinophilic infiltration on light microscopy. The plexus's ultimate obliteration results in chronic intestinal pseudo-obstruction (CIPO). EMG is almost exclusively seen in the pediatric population. The diagnosis of EMG is made through full-thickness rectal biopsy and EMG is not detectable through routine screening measures such as imaging or colonoscopy. The current treatment modality for this disorder is not standardized, and has often been treated with systemic steroids given its eosinophilic involvement. This case presents a 73-year-old male with chronic constipation presenting with new obstipation in the setting of recent orthopedic intervention requiring outpatient opioids. Admission radiographs were consistent with sigmoid volvulus. Following endoscopic detorsion, exploratory laparotomy revealed diffuse colonic dilation and distal ischemia requiring a Hartmann's procedure. Surgical pathology revealed EMG, increasing the complexity of subsequent surgical decision-making after his urgent operation.

Identifiants

pubmed: 37501639
doi: 10.1177/00031348231191198
doi:

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

5021-5023

Déclaration de conflit d'intérêts

Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Auteurs

Alyson Kim (A)

Drexel University College of Medicine, Philadelphia, PA, USA.

Jeffrey L Roberson (JL)

Department of Surgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.

Lillias H Maguire (LH)

Division of Colon and Rectal Surgery, Department of Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.
Corporal Michael J. Crescenz Memorial Veterans Affairs Medical Center, Philadelphia, PA, USA.

Bo Jian (B)

Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.

Nicole M Saur (NM)

Division of Colon and Rectal Surgery, Department of Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.

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Classifications MeSH