Iron deficiency in young basketball players: Is a 100 μg/L ferritin cut-off appropriate for iron supplementation?: Results of a randomized placebo-controlled study.


Journal

Clinical cardiology
ISSN: 1932-8737
Titre abrégé: Clin Cardiol
Pays: United States
ID NLM: 7903272

Informations de publication

Date de publication:
Sep 2023
Historique:
revised: 06 06 2023
received: 30 03 2023
accepted: 27 07 2023
medline: 2 10 2023
pubmed: 28 7 2023
entrez: 28 7 2023
Statut: ppublish

Résumé

Iron deficiency (ID) is one of the most common factors that may reduce sports performance, supplementation forms and doses are still not standardized in athletes. Our aim was to assess the iron status of young male basketball players and to study the effect of iron supplementation in a randomized placebo-controlled study. We hypothesized that due to the higher iron demand of athletes, the 100 μg/L ferritin cut-off may be appropriate to determine the non-anemic ID. During a sports cardiology screening, questionnaires, laboratory tests, electrocardiograms, echocardiography exams, and cardiopulmonary exercise tests were performed. Athletes with ID (ferritin <100 μg/L) were randomized into iron and placebo groups. Ferrous sulfate (containing 100 mg elemental iron [II] and 60 mg ascorbic acid) or placebo (50 mg vitamin C) was administered for 3 months. All exams were repeated after the supplementation period. We included 65 (age 15.8 ± 1.7 years) basketball players divided into four age groups. Non-anemic ID was observed in 60 (92%) athletes. After supplementation, ferritin levels were higher in the iron group (75.5 ± 25.9 vs. 54.9 ± 10.4 μg/L, p < .01). Ferritin >100 μg/L level was achieved only in 15% of the athletes. There were no differences in performance between the groups (VO As a result of the 3-month iron supplementation, the ferritin levels increased; however, only a small portion of the athletes achieved the target ferritin level, while performance improvement was not detectable.

Sections du résumé

BACKGROUND BACKGROUND
Iron deficiency (ID) is one of the most common factors that may reduce sports performance, supplementation forms and doses are still not standardized in athletes. Our aim was to assess the iron status of young male basketball players and to study the effect of iron supplementation in a randomized placebo-controlled study.
HYPOTHESIS OBJECTIVE
We hypothesized that due to the higher iron demand of athletes, the 100 μg/L ferritin cut-off may be appropriate to determine the non-anemic ID.
METHODS METHODS
During a sports cardiology screening, questionnaires, laboratory tests, electrocardiograms, echocardiography exams, and cardiopulmonary exercise tests were performed. Athletes with ID (ferritin <100 μg/L) were randomized into iron and placebo groups. Ferrous sulfate (containing 100 mg elemental iron [II] and 60 mg ascorbic acid) or placebo (50 mg vitamin C) was administered for 3 months. All exams were repeated after the supplementation period.
RESULTS RESULTS
We included 65 (age 15.8 ± 1.7 years) basketball players divided into four age groups. Non-anemic ID was observed in 60 (92%) athletes. After supplementation, ferritin levels were higher in the iron group (75.5 ± 25.9 vs. 54.9 ± 10.4 μg/L, p < .01). Ferritin >100 μg/L level was achieved only in 15% of the athletes. There were no differences in performance between the groups (VO
CONCLUSIONS CONCLUSIONS
As a result of the 3-month iron supplementation, the ferritin levels increased; however, only a small portion of the athletes achieved the target ferritin level, while performance improvement was not detectable.

Identifiants

pubmed: 37503875
doi: 10.1002/clc.24117
pmc: PMC10540028
doi:

Substances chimiques

Iron E1UOL152H7
Ferritins 9007-73-2
Apoferritins 9013-31-4
Hemoglobins 0

Types de publication

Randomized Controlled Trial Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1116-1123

Subventions

Organisme : Ministry of Innovation and Technology of Hungary from the National Research, Development and Innovation Fund
ID : TKP2021-NKTA-46
Organisme : Ministry of Innovation and Technology of Hungary from the National Research, Development and Innovation Fund
ID : TKP2021-NKTA
Organisme : European Union
ID : RRF-2.3.1-21-2022-00004 (MILAB)
Organisme : National Research, Development and Innovation Office
ID : K135076 to B.M.
Organisme : National Research, Development and Innovation Office
ID : K135076
Organisme : Thematic Excellence Programme (2020-4.1.1.-TKP2020) of the Ministry for Innovation and Technology in Hungary
ID : NKFIH-1277-2/2020

Informations de copyright

© 2023 The Authors. Clinical Cardiology published by Wiley Periodicals LLC.

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Auteurs

Emese Csulak (E)

Heart and Vascular Center, Semmelweis University, Budapest, Hungary.

Titanilla Takács (T)

Heart and Vascular Center, Semmelweis University, Budapest, Hungary.

Brigitta Babis (B)

Heart and Vascular Center, Semmelweis University, Budapest, Hungary.

Laura Horváth (L)

Department of Internal Medicine and Hematology, Semmelweis University, Budapest, Hungary.

Petra Márton (P)

Honvéd Basketball Academy, Budapest, Hungary.

Bálint Lakatos (B)

Heart and Vascular Center, Semmelweis University, Budapest, Hungary.

Attila Kovács (A)

Heart and Vascular Center, Semmelweis University, Budapest, Hungary.

Levente Staub (L)

Argus Cognitive, Inc., Lebanon, New Hampshire, USA.

Liliána Erzsébet Szabó (LE)

Heart and Vascular Center, Semmelweis University, Budapest, Hungary.

Zsófia Dohy (Z)

Heart and Vascular Center, Semmelweis University, Budapest, Hungary.

Hajnalka Vágó (H)

Heart and Vascular Center, Semmelweis University, Budapest, Hungary.
Department of Sports Medicine, Semmelweis University, Budapest, Hungary.

Béla Merkely (B)

Heart and Vascular Center, Semmelweis University, Budapest, Hungary.
Department of Sports Medicine, Semmelweis University, Budapest, Hungary.

Nóra Sydó (N)

Heart and Vascular Center, Semmelweis University, Budapest, Hungary.
Department of Sports Medicine, Semmelweis University, Budapest, Hungary.

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