A factor analytic comparison of three commonly used depression scales (HAMD, MADRS, BDI) in a large sample of depressed inpatients.

BDI CFA Clinician rating Confirmatory factor analysis EFA Exploratory factor analysis Factor structure HAMD MADRS Rating scale Self-report

Journal

BMC psychiatry
ISSN: 1471-244X
Titre abrégé: BMC Psychiatry
Pays: England
ID NLM: 100968559

Informations de publication

Date de publication:
28 07 2023
Historique:
received: 14 05 2023
accepted: 19 07 2023
medline: 31 7 2023
pubmed: 29 7 2023
entrez: 28 7 2023
Statut: epublish

Résumé

Quantifying depression mainly relies on the use of depression scales, and understanding their factor structure is crucial for evaluating their validity. This post-hoc analysis utilized prospectively collected data from a naturalistic study of 1014 inpatients with major depression. Confirmatory and exploratory factor analyses were performed to test the psychometric abilities of the Hamilton Depression Rating Scale, the Montgomery Asberg Depression Rating Scale, and the self-rated Beck Depression Inventory. A combined factor analysis was also conducted including all items of all scales. All three scales showed good to very good internal consistency. The HAMD-17 had four factors: an "anxiety" factor, a "depression" factor, an "insomnia" factor, and a "somatic" factor. The MADRS also had four factors: a "sadness" factor, a neurovegetative factor, a "detachment" factor and a "negative thoughts" factor, while the BDI had three factors: a "negative attitude towards self" factor, a "performance impairment" factor, and a "somatic" factor. The combined factor analysis suggested that self-ratings might reflect a distinct illness dimension within major depression. The factors obtained in this study are comparable to those found in previous research. Self and clinician ratings are complementary and not redundant, highlighting the importance of using multiple measures to quantify depression.

Sections du résumé

BACKGROUND
Quantifying depression mainly relies on the use of depression scales, and understanding their factor structure is crucial for evaluating their validity.
METHODS
This post-hoc analysis utilized prospectively collected data from a naturalistic study of 1014 inpatients with major depression. Confirmatory and exploratory factor analyses were performed to test the psychometric abilities of the Hamilton Depression Rating Scale, the Montgomery Asberg Depression Rating Scale, and the self-rated Beck Depression Inventory. A combined factor analysis was also conducted including all items of all scales.
RESULTS
All three scales showed good to very good internal consistency. The HAMD-17 had four factors: an "anxiety" factor, a "depression" factor, an "insomnia" factor, and a "somatic" factor. The MADRS also had four factors: a "sadness" factor, a neurovegetative factor, a "detachment" factor and a "negative thoughts" factor, while the BDI had three factors: a "negative attitude towards self" factor, a "performance impairment" factor, and a "somatic" factor. The combined factor analysis suggested that self-ratings might reflect a distinct illness dimension within major depression.
CONCLUSIONS
The factors obtained in this study are comparable to those found in previous research. Self and clinician ratings are complementary and not redundant, highlighting the importance of using multiple measures to quantify depression.

Identifiants

pubmed: 37507656
doi: 10.1186/s12888-023-05038-7
pii: 10.1186/s12888-023-05038-7
pmc: PMC10386606
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

548

Informations de copyright

© 2023. The Author(s).

Références

Psychol Med. 1999 Mar;29(2):447-56
pubmed: 10218936
Encephale. 2019 Jun;45(3):195-199
pubmed: 30122299
Int J Geriatr Psychiatry. 2003 Jan;18(1):73-7
pubmed: 12497559
Depression. 1996;4(1):31-3
pubmed: 9160651
Arch Psychiatr Nervenkr (1970). 1976 Dec 30;222(4):359-75
pubmed: 1016014
Psychopharmacol Ser. 1990;9:80-92
pubmed: 2399249
Int Clin Psychopharmacol. 2012 Sep;27(5):249-55
pubmed: 22869009
J Affect Disord. 2002 Feb;68(1):41-7
pubmed: 11869781
Int J Geriatr Psychiatry. 1997 Jul;12(7):760-4
pubmed: 9251940
Psychopharmacology (Berl). 2000 Jul;150(4):399-403
pubmed: 10958081
J Clin Psychol. 2006 Jan;62(1):123-46
pubmed: 16287149
Arch Gen Psychiatry. 1961 Jun;4:561-71
pubmed: 13688369
Acta Psychiatr Scand. 1967;43(3):255-66
pubmed: 5585152
Am J Psychiatry. 2008 Mar;165(3):342-51
pubmed: 18172020
Schweiz Arch Neurol Psychiatr (1985). 1988;139(2):51-65
pubmed: 2455937
J Affect Disord. 2011 Sep;133(1-2):137-49
pubmed: 21555156
Eur Arch Psychiatry Neurol Sci. 1985;234(6):417-22
pubmed: 4029226
Int J Methods Psychiatr Res. 2013 Sep;22(3):175-84
pubmed: 24038301
J Affect Disord. 2006 Jun;92(2-3):261-6
pubmed: 16563521
Eur Arch Psychiatry Clin Neurosci. 2009 Feb;259(1):55-63
pubmed: 18806921
Nervenarzt. 1991 Nov;62(11):689-96
pubmed: 1770969
Eur Psychiatry. 2020 Sep 23;63(1):e91
pubmed: 32962793
Int J Geriatr Psychiatry. 1998 Apr;13(4):257-61
pubmed: 9646154
J Clin Psychiatry. 2010 Aug;71(8):1047-54
pubmed: 20673545
Arch Gen Psychiatry. 1972 Jun;26(6):546-52
pubmed: 5027118
Int J Methods Psychiatr Res. 2018 Mar;27(1):
pubmed: 29498147
Prog Neuropsychopharmacol Biol Psychiatry. 2001 Oct;25(7):1369-76
pubmed: 11513352
Neurochem Int. 2003 Sep-Oct;43(4-5):481-92
pubmed: 12742095
J Affect Disord. 2008 Jun;108(3):271-8
pubmed: 18164767
Psychol Med. 2008 Feb;38(2):289-300
pubmed: 17922940
Eur Neuropsychopharmacol. 2006 Dec;16(8):601-11
pubmed: 16769204
J Psychiatr Res. 2004 May-Jun;38(3):275-84
pubmed: 15003433
Br J Psychiatry. 1979 Apr;134:382-9
pubmed: 444788
Psychopathology. 1998;31(3):160-8
pubmed: 9636945
Am J Psychiatry. 2004 Dec;161(12):2163-77
pubmed: 15569884
J Affect Disord. 2021 Dec 1;295:639-646
pubmed: 34509779
Acta Psychiatr Scand. 1995 Sep;92(3):168-72
pubmed: 7484192
Int Clin Psychopharmacol. 2002 Nov;17(6):281-5
pubmed: 12409681
World J Biol Psychiatry. 2007;8(2):67-104
pubmed: 17455102
Acta Psychiatr Scand. 2021 Jan;143(1):36-49
pubmed: 33141944
Int Clin Psychopharmacol. 1995 Sep;10(3):157-61
pubmed: 8675968
Eur Arch Psychiatry Clin Neurosci. 2016 Dec;266(8):725-736
pubmed: 27002521
Am J Psychiatry. 2000 Apr;157(4 Suppl):1-45
pubmed: 10767867
J Affect Disord. 1993 Apr;27(4):255-65
pubmed: 8509526
J Affect Disord. 2002 Aug;70(3):313-7
pubmed: 12128243
J Geriatr Psychiatry Neurol. 2016 May;29(3):115-9
pubmed: 26392481
Int J Methods Psychiatr Res. 2022 Dec;31(4):e1927
pubmed: 35749277
J Affect Disord. 2021 Sep 1;292:36-44
pubmed: 34091381
Br J Psychiatry. 1981 Mar;138:201-4
pubmed: 7272610
Asian J Psychiatr. 2017 Aug;28:154-159
pubmed: 28784374
Acta Psychiatr Scand. 1990 Aug;82(2):178-81
pubmed: 2239363
BMC Psychiatry. 2015 Aug 19;15:200
pubmed: 26286597
Mod Probl Pharmacopsychiatry. 1974;7(0):151-69
pubmed: 4412100
Psychol Assess. 2009 Dec;21(4):476-85
pubmed: 19947782
Int J Geriatr Psychiatry. 2004 Dec;19(12):1168-72
pubmed: 15526303
Prim Care Companion J Clin Psychiatry. 2009;11(1):8-15
pubmed: 19333404
Eur Psychiatry. 2000 May;15(3):160-72
pubmed: 10881213
Eur Neuropsychopharmacol. 2010 May;20(5):346-55
pubmed: 20097046
Psychopathology. 1995;28(6):291-306
pubmed: 8838401
Depress Anxiety. 2005;21(2):95-7
pubmed: 15884092
Am J Psychiatry. 2006 Nov;163(11):1905-17
pubmed: 17074942
J Affect Disord. 2014 Jul;163:81-7
pubmed: 24836092
Pharmacopsychiatry. 1991 May;24(3):71-5
pubmed: 1891483
Arch Womens Ment Health. 2013 Apr;16(2):159-66
pubmed: 23420273

Auteurs

Florian Seemüller (F)

Department of Psychiatry and Psychotherapy, University Hospital, Ludwig-Maximilians-University, Nussbaumstrasse 7, 80336, Munich, Germany. florian.seemueller@kbo.de.
Department of Psychiatry, Psychotherapy and Psychosomatics, Kbo-Lech-Mangfall-Klinik, Auenstrasse 6, 82467, Garmisch-Partenkirchen, Germany. florian.seemueller@kbo.de.

Rebecca Schennach (R)

Department of Psychiatry and Psychotherapy, University Hospital, Ludwig-Maximilians-University, Nussbaumstrasse 7, 80336, Munich, Germany.
Schoen Clinic Roseneck, Am Roseneck 6, 83209, Prien am Chiemsee, Germany.

Richard Musil (R)

Department of Psychiatry and Psychotherapy, University Hospital, Ludwig-Maximilians-University, Nussbaumstrasse 7, 80336, Munich, Germany.

Michael Obermeier (M)

Department of Psychiatry and Psychotherapy, University Hospital, Ludwig-Maximilians-University, Nussbaumstrasse 7, 80336, Munich, Germany.

Mazda Adli (M)

Department of Psychiatry and Psychotherapy, Charité - Universitätsmedizin Berlin, Charité Mitte (CCM), CampusCharitéplatz 1, 10117, Berlin, Germany.
Center for Psychiatry, Psychotherapy and Psychosomatic Medicine, Fliedner Klinik Berlin, Markgrafenstrasse 34, 10117, Berlin, Germany.

Michael Bauer (M)

Department of Psychiatry and Psychotherapy, Carl Gustav Carus University Hospital Dresden, Technische Universität Dresden, Fetscherstrasse 74, 01307, Dresden, Germany.

Peter Brieger (P)

Department of Psychiatry and Psychotherapy, University Hospital, Ludwig-Maximilians-University, Nussbaumstrasse 7, 80336, Munich, Germany.
Department of Psychiatry and Psychotherapy, Kbo-Isar-Amper-Klinikum Region Munich, Vockestrasse 72, 85540, Haar, Germany.

Gerd Laux (G)

Department of Psychiatry and Psychotherapy, University Hospital, Ludwig-Maximilians-University, Nussbaumstrasse 7, 80336, Munich, Germany.
Institute of Psychological Medicine (IPM), Nussbaumstrasse 9, 83564, Soyen, Germany.

Wolfgang Gaebel (W)

Department of Psychiatry and Psychotherapy, University of Düsseldorf, Bergische Landstrasse 2, 40629, Düsseldorf, Germany.

Peter Falkai (P)

Department of Psychiatry and Psychotherapy, University Hospital, Ludwig-Maximilians-University, Nussbaumstrasse 7, 80336, Munich, Germany.

Michael Riedel (M)

Department of Psychiatry and Psychotherapy, University Hospital, Ludwig-Maximilians-University, Nussbaumstrasse 7, 80336, Munich, Germany.
Centre for Disturbance of Memory and Demetia, Marion von Tessin Memory-Centre, Nymphenburgerstrasse 45, 80636, Munich, Germany.

Hans-Jürgen Möller (HJ)

Department of Psychiatry and Psychotherapy, University Hospital, Ludwig-Maximilians-University, Nussbaumstrasse 7, 80336, Munich, Germany.

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