Structural Modification and Biological Activity of Polysaccharides.

Spectroscopy, Fourier Transform Infrared Polysaccharides / pharmacology Antioxidants / chemistry Magnetic Resonance Spectroscopy Phosphorylation
biological activity polysaccharide structural characterization structural modification

Journal

Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009

Informations de publication

Date de publication:
14 Jul 2023
Historique:
received: 20 06 2023
revised: 10 07 2023
accepted: 12 07 2023
medline: 31 7 2023
pubmed: 29 7 2023
entrez: 29 7 2023
Statut: epublish

Résumé

Natural polysaccharides are macromolecular substances with a wide range of biological activities. The structural modification of polysaccharides by chemical means can enhance their biological activity. This paper reviews the latest research reports on the chemical modification of natural polysaccharides. At present, the modification methods of polysaccharides mainly include sulfation, phosphorylation, carboxymethylation, socialization, methylation and acetylation. The chemical and physical structures of the modified polysaccharides were detected via ultraviolet spectroscopy, FT-IR, high-performance liquid chromatography, ultraviolet spectroscopy, gas chromatography-mass spectrometry, nuclear magnetic resonance and scanning electron microscopy. Modern pharmacological studies have shown that the modified polysaccharide has various biological activities, such as antioxidant, antitumor, immune regulation, antiviral, antibacterial and anticoagulant functions in vitro. This review provides fresh ideas for the research and application of polysaccharide structure modification.

Identifiants

DOI: 10.3390/molecules28145416 PMID: 37513287 PMC: PMC10384959
pubmed: 37513287
pii: molecules28145416
doi: 10.3390/molecules28145416
pmc: PMC10384959
pii:
doi:

Substances chimiques

Polysaccharides 0
Antioxidants 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

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Auteurs

Ting Zhao (T)

College of Traditional Chinese Medicine, Jilin Agriculture Science and Technology College, Jilin 132101, China.
Scientific and Technological Innovation Center of Health Products and Medical Materials with Characteristic Resources of Jilin Province, Jilin Agricultural University, Changchun 130118, China.

Min Yang (M)

College of Traditional Chinese Medicine, Jilin Agriculture Science and Technology College, Jilin 132101, China.
Scientific and Technological Innovation Center of Health Products and Medical Materials with Characteristic Resources of Jilin Province, Jilin Agricultural University, Changchun 130118, China.

Lina Ma (L)

College of Traditional Chinese Medicine, Jilin Agriculture Science and Technology College, Jilin 132101, China.
Scientific and Technological Innovation Center of Health Products and Medical Materials with Characteristic Resources of Jilin Province, Jilin Agricultural University, Changchun 130118, China.

Xinglong Liu (X)

College of Traditional Chinese Medicine, Jilin Agriculture Science and Technology College, Jilin 132101, China.
Scientific and Technological Innovation Center of Health Products and Medical Materials with Characteristic Resources of Jilin Province, Jilin Agricultural University, Changchun 130118, China.

Qiteng Ding (Q)

Scientific and Technological Innovation Center of Health Products and Medical Materials with Characteristic Resources of Jilin Province, Jilin Agricultural University, Changchun 130118, China.
College of Chinese Medicinal Materials, Jilin Agricultural University, Changchun 130118, China.

Guodong Chai (G)

Scientific and Technological Innovation Center of Health Products and Medical Materials with Characteristic Resources of Jilin Province, Jilin Agricultural University, Changchun 130118, China.
College of Resources and Environment, Jilin Agricultural University, Changchun 130118, China.

Yang Lu (Y)

Scientific and Technological Innovation Center of Health Products and Medical Materials with Characteristic Resources of Jilin Province, Jilin Agricultural University, Changchun 130118, China.
College of Resources and Environment, Jilin Agricultural University, Changchun 130118, China.

Hewei Wei (H)

Scientific and Technological Innovation Center of Health Products and Medical Materials with Characteristic Resources of Jilin Province, Jilin Agricultural University, Changchun 130118, China.
College of Chinese Medicinal Materials, Jilin Agricultural University, Changchun 130118, China.

Shuai Zhang (S)

Scientific and Technological Innovation Center of Health Products and Medical Materials with Characteristic Resources of Jilin Province, Jilin Agricultural University, Changchun 130118, China.
College of Chinese Medicinal Materials, Jilin Agricultural University, Changchun 130118, China.

Chuanbo Ding (C)

College of Traditional Chinese Medicine, Jilin Agriculture Science and Technology College, Jilin 132101, China.
Scientific and Technological Innovation Center of Health Products and Medical Materials with Characteristic Resources of Jilin Province, Jilin Agricultural University, Changchun 130118, China.

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Classifications MeSH

questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Analyse spectrale › Spectrophotométrie › Spectrophotométrie IR › Spectroscopie infrarouge à transformée de Fourier › Structural Modification and Biological...
questionsmedicales.fr › Glucides › Polyosides › Structural Modification and Biological...
questionsmedicales.fr › Actions chimiques et utilisations › Utilisations spécialisées de produits chimiques › Agents protecteurs › Antioxydants › Structural Modification and Biological...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Analyse spectrale › Spectroscopie par résonance magnétique › Structural Modification and Biological...
questionsmedicales.fr › Métabolisme › Phosphorylation › Structural Modification and Biological...