A Review of the Popular Uses, Anatomical, Chemical, and Biological Aspects of Kalanchoe (Crassulaceae): A Genus of Plants Known as "Miracle Leaf".
Crassulaceae
Kalanchoe
bioactive compounds
botanical description
chemical composition
natural products
pharmacological activities
traditional use
Journal
Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009
Informations de publication
Date de publication:
21 Jul 2023
21 Jul 2023
Historique:
received:
19
06
2023
revised:
15
07
2023
accepted:
19
07
2023
medline:
31
7
2023
pubmed:
29
7
2023
entrez:
29
7
2023
Statut:
epublish
Résumé
Species of the genus Kalanchoe have a long history of therapeutic use in ethnomedicine linked to their remarkable healing properties. Several species have chemical and anatomical similarities, often leading to confusion when they are used in folk medicine. This review aims to provide an overview and discussion of the reported traditional uses, botanical aspects, chemical constituents, and pharmacological potential of the Kalanchoe species. Published scientific materials were collected from the PubMed and SciFinder databases without restriction regarding the year of publication through April 2023. Ethnopharmacological knowledge suggests that these species have been used to treat infections, inflammation, injuries, and other disorders. Typically, all parts of the plant are used for medicinal purposes either as crude extract or juice. Botanical evaluation can clarify species differentiation and can enable correct identification and validation of the scientific data. Flavonoids are the most common classes of secondary metabolites identified from Kalanchoe species and can be correlated with some biological studies (antioxidant, anti-inflammatory, and antimicrobial potential). This review summarizes several topics related to the Kalanchoe genus, supporting future studies regarding other unexplored research areas. The need to conduct further studies to confirm the popular uses and biological activities of bioactive compounds is also highlighted.
Identifiants
pubmed: 37513446
pii: molecules28145574
doi: 10.3390/molecules28145574
pmc: PMC10383218
pii:
doi:
Substances chimiques
Phytochemicals
0
Plant Extracts
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Coordenação de Aperfeicoamento de Pessoal de Nível Superior
ID : 8881.689971/2022-01
Références
Org Lett. 2006 Nov 9;8(23):5207-10
pubmed: 17078679
Molecules. 2022 Mar 31;27(7):
pubmed: 35408681
PLoS One. 2022 Mar 9;17(3):e0264987
pubmed: 35263358
Phytochem Anal. 2018 May;29(3):308-315
pubmed: 29349835
BMC Complement Altern Med. 2012 Sep 10;12:149
pubmed: 22963191
Planta Med. 1985 Apr;(2):169-70
pubmed: 3839925
BMC Complement Altern Med. 2012 Mar 10;12:15
pubmed: 22405256
Nat Prod Commun. 2012 Feb;7(2):175-8
pubmed: 22474947
Eur J Obstet Gynecol Reprod Biol. 2004 Apr 15;113(2):164-71
pubmed: 15063954
J Ethnopharmacol. 2014 Jun 11;154(2):330-8
pubmed: 24727190
Evid Based Complement Alternat Med. 2014;2014:429256
pubmed: 25580151
Pharm Biol. 2016 Dec;54(12):3182-3188
pubmed: 27488985
Genet Mol Res. 2016 Feb 11;15(1):
pubmed: 26909971
Beni Suef Univ J Basic Appl Sci. 2022;11(1):96
pubmed: 35966214
J Nat Prod. 1989 Sep-Oct;52(5):1071-9
pubmed: 2607348
Nat Prod Res. 2021 Dec;35(24):6034-6039
pubmed: 32924590
J Toxicol. 2018 Jan 21;2018:6849765
pubmed: 29593788
Plants (Basel). 2022 Jun 29;11(13):
pubmed: 35807674
Pharm Biol. 2017 Dec;55(1):1586-1591
pubmed: 28395583
Prikl Biokhim Mikrobiol. 2016 Jul-Aug;52(4):402-9
pubmed: 29512985
J Exp Bot. 2019 Feb 20;70(4):1367-1374
pubmed: 30576518
Planta Med. 2013 Sep;79(14):1362-9
pubmed: 23877916
Int J Hypertens. 2015;2015:579497
pubmed: 26495138
Microsc Microanal. 2010 Oct;16(5):576-82
pubmed: 20670464
Biomed Res Int. 2023 Feb 20;2023:1977602
pubmed: 36860811
Neurologia. 2016 Apr;31(3):161-8
pubmed: 26300500
Planta Med. 2006 Jan;72(1):81-3
pubmed: 16450304
J Pharm Bioallied Sci. 2015 Jan-Mar;7(1):26-31
pubmed: 25709333
Phytochemistry. 2009 May;70(7):899-906
pubmed: 19446855
BMC Res Notes. 2012 Mar 20;5:158
pubmed: 22433844
J Ethnopharmacol. 2003 Jun;86(2-3):197-202
pubmed: 12738087
J Ethnopharmacol. 2018 Aug 10;222:133-147
pubmed: 29730133
J Ethnobiol Ethnomed. 2022 Jun 21;18(1):48
pubmed: 35729583
Heliyon. 2023 Apr 07;9(4):e15361
pubmed: 37077674
Trop Med Health. 2023 Jan 9;51(1):1
pubmed: 36617576
BMC Complement Altern Med. 2017 May 25;17(1):280
pubmed: 28545532
Molecules. 2016 Feb 24;21(3):243
pubmed: 26927036
ScientificWorldJournal. 2021 Apr 27;2021:6649574
pubmed: 33994883
Drug Chem Toxicol. 2022 Jan;45(1):360-366
pubmed: 31791148
Saudi J Biol Sci. 2018 May;25(4):622-630
pubmed: 29740226
Planta Med. 1973 Mar;23(2):149-53
pubmed: 4705794
Nat Prod Bioprospect. 2018 Apr;8(2):97-105
pubmed: 29453613
J Pharmacopuncture. 2022 Sep 30;25(3):149-185
pubmed: 36186100
Phytomedicine. 2012 Jan 15;19(2):115-21
pubmed: 21802918
Evid Based Complement Alternat Med. 2012;2012:503165
pubmed: 22666293
Evid Based Complement Alternat Med. 2022 Sep 19;2022:7328613
pubmed: 36193157
Environ Toxicol. 2016 Nov;31(11):1663-1673
pubmed: 26179408
Evid Based Complement Alternat Med. 2022 Jun 27;2022:2935015
pubmed: 35795271
J Pharm Pharmacol. 2015 Jul;67(7):951-62
pubmed: 25827848
Int Immunopharmacol. 2002 Jun;2(7):875-83
pubmed: 12188029
Mutat Res Genet Toxicol Environ Mutagen. 2020 Aug - Sep;856-857:503229
pubmed: 32928369
Parasitology. 2010 Apr;137(4):613-8
pubmed: 19961648
Planta Med. 2013 Nov;79(16):1565-71
pubmed: 24072500
Drug Metab Lett. 2015;9(1):48-62
pubmed: 25600201
Plants (Basel). 2022 May 23;11(10):
pubmed: 35631812
Biomed Pharmacother. 2019 May;113:108721
pubmed: 30856538
J Immunol Res. 2017;2017:4645701
pubmed: 28326334
Photochem Photobiol. 2013 Mar-Apr;89(2):391-9
pubmed: 23057576
J Pharm Biomed Anal. 2021 Jan 30;193:113682
pubmed: 33166841
Biomed Pharmacother. 2018 May;101:8-13
pubmed: 29459294
Front Pharmacol. 2021 Dec 16;12:744192
pubmed: 34975468
Indian J Pharmacol. 2012 Sep-Oct;44(5):566-70
pubmed: 23112414
Int J Mol Sci. 2023 Mar 25;24(7):
pubmed: 37047182
Pharm Biol. 2013 Nov;51(11):1411-8
pubmed: 23865837
Indian J Exp Biol. 2010 Jun;48(6):572-6
pubmed: 20882759
J Ethnopharmacol. 2014 Feb 3;151(2):891-6
pubmed: 24315852
Int Immunopharmacol. 2008 Dec 10;8(12):1616-21
pubmed: 18675940
J Exp Bot. 2010 Mar;61(5):1375-83
pubmed: 20159885
Planta Med. 2020 Mar;86(4):239-246
pubmed: 31994149
Front Nutr. 2022 Jun 16;9:924596
pubmed: 35782945
Molecules. 2020 Sep 14;25(18):
pubmed: 32937751
Chem Biodivers. 2016 Dec;13(12):1707-1714
pubmed: 27472283
J Nat Prod. 2006 May;69(5):815-8
pubmed: 16724848
Plant Cell Rep. 2010 Jan;29(1):61-77
pubmed: 19921199
Heliyon. 2022 Aug 13;8(8):e10211
pubmed: 36033288
Biosci Biotechnol Biochem. 2000 Jun;64(6):1310-2
pubmed: 10923811
J Nat Prod. 1994 Nov;57(11):1503-10
pubmed: 7853000
Phytother Res. 2003 Aug;17(7):801-3
pubmed: 12916081
An Acad Bras Cienc. 2011 Dec;83(4):1435-42
pubmed: 22146966
Planta Med. 2017 Nov;83(16):1274-1280
pubmed: 28437806
J Ethnopharmacol. 2006 Jun 15;106(1):70-5
pubmed: 16423479
Planta Med. 2015 Aug;81(12-13):1190-7
pubmed: 26132852
J Plant Physiol. 2011 Nov 15;168(17):2021-7
pubmed: 21856038
Phytomedicine. 2014 Apr 15;21(5):753-7
pubmed: 24373544
Pak J Pharm Sci. 2016 Jul;29(4):1321-4
pubmed: 27393455
Toxicol Rep. 2021 Dec 10;9:22-35
pubmed: 34976744
An Acad Bras Cienc. 2012 Mar;84(1):211-8
pubmed: 22441611
Am J Chin Med. 2010;38(3):529-46
pubmed: 20503470
Anal Bioanal Chem. 2010 Oct;398(3):1329-38
pubmed: 20714893
Planta Med. 2000 Mar;66(2):134-7
pubmed: 10763586
BMC Complement Altern Med. 2018 Jul 13;18(1):214
pubmed: 30005652
Evid Based Complement Alternat Med. 2019 Jan 2;2019:6340757
pubmed: 30719063
Food Chem Toxicol. 2000 May;38(5):417-21
pubmed: 10762727
Clin Exp Gastroenterol. 2022 Sep 24;15:171-187
pubmed: 36186925
Molecules. 2022 Sep 29;27(19):
pubmed: 36234962
Biosci Biotechnol Biochem. 2001 Apr;65(4):947-9
pubmed: 11388478
Int J Biol Macromol. 2018 Dec;120(Pt B):1591-1600
pubmed: 30261260
Sci Rep. 2020 Feb 21;10(1):3143
pubmed: 32081991
Oxid Med Cell Longev. 2019 Nov 11;2019:9245951
pubmed: 31827708
Nat Commun. 2017 Dec 1;8(1):1899
pubmed: 29196618
Front Pharmacol. 2020 Oct 28;11:566334
pubmed: 33192509
Front Plant Sci. 2022 Sep 23;13:991557
pubmed: 36212372
J Photochem Photobiol B. 2015 Jul;148:73-81
pubmed: 25900552
PLoS One. 2016 Dec 29;11(12):e0168658
pubmed: 28033347
J Ethnopharmacol. 2015 Sep 15;173:338-51
pubmed: 26232628
Colloids Surf B Biointerfaces. 2019 Aug 1;180:141-149
pubmed: 31039515
Eur J Obstet Gynecol Reprod Biol. 2006 Feb 1;124(2):168-72
pubmed: 16051414
Pharmaceuticals (Basel). 2020 Dec 04;13(12):
pubmed: 33291844
Pharm Biol. 2020 Dec;58(1):732-740
pubmed: 32715869
J Ethnopharmacol. 2014 Apr 28;153(2):400-7
pubmed: 24583107
ScientificWorldJournal. 2022 Apr 12;2022:8657249
pubmed: 35463824
Planta Med. 2016 Jul;82(11-12):930-41
pubmed: 27220081
EXCLI J. 2017 Apr 24;16:593-601
pubmed: 28694760
J Ethnopharmacol. 2022 Jan 30;283:114640
pubmed: 34606947
Iran J Parasitol. 2021 Jul-Sep;16(3):394-401
pubmed: 34630584
Plants (Basel). 2023 Mar 02;12(5):
pubmed: 36904005
Int J Mol Sci. 2018 Apr 24;19(5):
pubmed: 29695040
Microsc Microanal. 2020 Oct;26(5):1061-1068
pubmed: 32811591
Plants (Basel). 2022 Nov 16;11(22):
pubmed: 36432868
Front Pharmacol. 2023 Jan 12;13:1104705
pubmed: 36712663
Front Pharmacol. 2021 Feb 18;12:632986
pubmed: 33679416
Front Pharmacol. 2019 Feb 06;10:67
pubmed: 30792655
J Ethnopharmacol. 2009 Apr 21;122(3):523-32
pubmed: 19429323
Aust Vet J. 1987 Oct;64(10):298-301
pubmed: 3439945
Phytother Res. 1999 Jun;13(4):352-4
pubmed: 10404548
Integr Cancer Ther. 2015 Sep;14(5):452-9
pubmed: 25873294
Am J Chin Med. 2011;39(6):1275-90
pubmed: 22083996
J Ethnopharmacol. 2011 Jan 7;133(1):132-7
pubmed: 20883762
Phytochemistry. 2005 Dec;66(24):2829-35
pubmed: 16297414
J Immunol Res. 2017;2017:3940743
pubmed: 28695135
Phytochem Rev. 2017;16(6):1155-1171
pubmed: 29200987
Sci Rep. 2019 Dec 24;9(1):19786
pubmed: 31875020