Core Warming of Coronavirus Disease 2019 Patients Undergoing Mechanical Ventilation: A Pilot Study.
COVID-19
esophageal warming
induced hyperthermia
respiratory insufficiency
sepsis
virus replication
Journal
Therapeutic hypothermia and temperature management
ISSN: 2153-7933
Titre abrégé: Ther Hypothermia Temp Manag
Pays: United States
ID NLM: 101543518
Informations de publication
Date de publication:
Dec 2023
Dec 2023
Historique:
medline:
4
12
2023
pubmed:
1
8
2023
entrez:
1
8
2023
Statut:
ppublish
Résumé
Fever is a recognized protective factor in patients with sepsis, and growing data suggest beneficial effects on outcomes in sepsis with elevated temperature, with a recent pilot randomized controlled trial (RCT) showing lower mortality by warming afebrile sepsis patients in the intensive care unit (ICU). The objective of this prospective single-site RCT was to determine if core warming improves respiratory physiology of mechanically ventilated patients with coronavirus disease 2019 (COVID-19), allowing earlier weaning from ventilation, and greater overall survival. A total of 19 patients with mean age of 60.5 (±12.5) years, 37% female, mean weight 95.1 (±18.6) kg, and mean body mass index 34.5 (±5.9) kg/m
Identifiants
pubmed: 37527424
doi: 10.1089/ther.2023.0030
pmc: PMC10698775
doi:
Substances chimiques
Oxygen
S88TT14065
Banques de données
ClinicalTrials.gov
['NCT04494867']
Types de publication
Randomized Controlled Trial
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
225-229Références
BMJ. 2003 Apr 19;326(7394):850-2
pubmed: 12702616
Shock. 2018 Oct;50(4):381-387
pubmed: 29240644
Ther Hypothermia Temp Manag. 2022 Nov;12(4):235-239
pubmed: 36301260
Burns. 2023 Mar;49(2):401-407
pubmed: 35513952
Arch Intern Med. 2001 Jan 8;161(1):121-3
pubmed: 11146708
Chest. 2013 Oct;144(4):1098-1101
pubmed: 24081340
N Engl J Med. 2020 Mar 19;382(12):1177-1179
pubmed: 32074444
Europace. 2023 May 19;25(5):
pubmed: 37096813
Curr Opin Anaesthesiol. 2021 Apr 1;34(2):119-124
pubmed: 33470663
Crit Care Med. 2009 Jul;37(7 Suppl):S203-10
pubmed: 19535948
Lancet Respir Med. 2018 Mar;6(3):183-192
pubmed: 29325753
J Pediatr. 1989 Jun;114(6):1045-8
pubmed: 2656959
Crit Care Med. 2017 May;45(5):806-813
pubmed: 28221185
N Engl J Med. 2015 Dec 3;373(23):2215-24
pubmed: 26436473
J Virol. 2019 Dec 12;94(1):
pubmed: 31597759
Crit Care Resusc. 2018 Jun;20(2):150-163
pubmed: 29852854
Curr Opin Crit Care. 2022 Dec 1;28(6):638-644
pubmed: 36226716
Crit Care. 2019 Mar 7;23(1):69
pubmed: 30845977
Intensive Care Med. 2019 Apr;45(4):468-476
pubmed: 30741326
Crit Care. 2011;15(3):222
pubmed: 21672276
Lancet. 2020 Mar 28;395(10229):1054-1062
pubmed: 32171076
PLoS One. 2012;7(1):e30077
pubmed: 22253887
Crit Care Med. 2022 Jun 1;50(6):924-934
pubmed: 35120040
PLoS One. 2015 Feb 24;10(2):e0117279
pubmed: 25710375
SAGE Open Med. 2020 Jun 03;8:2050312120928732
pubmed: 32547753
Lancet. 1997 Sep 6;350(9079):704-9
pubmed: 9291905
PLoS One. 2020 Dec 1;15(12):e0243190
pubmed: 33259540
Adv Virol. 2011;2011:734690
pubmed: 22312351
PLoS One. 2017 Jan 12;12(1):e0170152
pubmed: 28081244
Surg Infect (Larchmt). 2005 Winter;6(4):369-75
pubmed: 16433601
Gastroenterology Res. 2023 Jun;16(3):157-164
pubmed: 37351083
Nat Rev Immunol. 2015 Jun;15(6):335-49
pubmed: 25976513
Proc Natl Acad Sci U S A. 2015 Jan 20;112(3):827-32
pubmed: 25561542
JAMA. 2020 May 12;323(18):1843-1844
pubmed: 32159775
JAMA. 1975 Mar 24;231(12):1248-51
pubmed: 163931