Enhanced single-base mutation diversity by the combination of cytidine deaminase with DNA-repairing enzymes in yeast.
Saccharomyces cerevisiae
T7 promoter
cytidine deaminase fusion
mutagenesis
synthetic biology
Journal
Biotechnology journal
ISSN: 1860-7314
Titre abrégé: Biotechnol J
Pays: Germany
ID NLM: 101265833
Informations de publication
Date de publication:
Nov 2023
Nov 2023
Historique:
revised:
20
07
2023
received:
26
03
2023
accepted:
28
07
2023
medline:
13
11
2023
pubmed:
2
8
2023
entrez:
2
8
2023
Statut:
ppublish
Résumé
The occurrence of random mutations can increase the diversity of the genome and promote the evolutionary process of organisms. High efficiency mutagenesis techniques significantly accelerate the evolutionary process. In this work, we describe a targeted mutagenesis system named MutaT7
Identifiants
pubmed: 37529889
doi: 10.1002/biot.202300137
doi:
Substances chimiques
Cytidine Deaminase
EC 3.5.4.5
DNA
9007-49-2
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e2300137Subventions
Organisme : National Key Research and Development Program of China
ID : 2018YFA0900100
Organisme : Tianjin Fund for Distinguished Young Scholars
ID : 19JCJQJC63300
Informations de copyright
© 2023 Wiley-VCH GmbH.
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