Colonoscopy in the young: An indication-based analysis of outcome.


Journal

Journal of investigative medicine : the official publication of the American Federation for Clinical Research
ISSN: 1708-8267
Titre abrégé: J Investig Med
Pays: England
ID NLM: 9501229

Informations de publication

Date de publication:
12 2023
Historique:
medline: 6 11 2023
pubmed: 2 8 2023
entrez: 2 8 2023
Statut: ppublish

Résumé

Data on colonoscopy's diagnostic yield in young adults with lower gastrointestinal symptoms are scarce. We evaluated this yield in young patients by performing an indication-based analysis of outcomes. We reviewed diagnostic colonoscopies performed in young adults (age <50 years) over 10 years. We created two groups of young adults (18-39 years, n = 4941) and quadragenarians (40-49 years; n = 6605), included a control group of average-risk patients referred for screening colonoscopies during the same period (50-60 years, n = 1453). We evaluated clinical indications for colonoscopies among the young and performed an indication-based analysis of patients' outcomes. Chronic diarrhea and abdominal pain (42.4 and 36.2%), rectal bleeding (19.8 and 18.4%), and constipation were major indications for colonoscopy performance in quadragenarian and younger patients, respectively. Overall, diverticulosis (8.7 vs 1.3 and 3.9%; p We outlined the expected diagnostic yields of colonoscopy performed in young patients for multiple indications, showing that rectal bleeding was consistently associated with CRC and polyp detection.

Sections du résumé

BACKGROUND
Data on colonoscopy's diagnostic yield in young adults with lower gastrointestinal symptoms are scarce. We evaluated this yield in young patients by performing an indication-based analysis of outcomes.
METHODS
We reviewed diagnostic colonoscopies performed in young adults (age <50 years) over 10 years. We created two groups of young adults (18-39 years, n = 4941) and quadragenarians (40-49 years; n = 6605), included a control group of average-risk patients referred for screening colonoscopies during the same period (50-60 years, n = 1453). We evaluated clinical indications for colonoscopies among the young and performed an indication-based analysis of patients' outcomes.
RESULTS
Chronic diarrhea and abdominal pain (42.4 and 36.2%), rectal bleeding (19.8 and 18.4%), and constipation were major indications for colonoscopy performance in quadragenarian and younger patients, respectively. Overall, diverticulosis (8.7 vs 1.3 and 3.9%; p
CONCLUSION
We outlined the expected diagnostic yields of colonoscopy performed in young patients for multiple indications, showing that rectal bleeding was consistently associated with CRC and polyp detection.

Identifiants

pubmed: 37530168
doi: 10.1177/10815589231193953
doi:

Types de publication

Review Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

797-803

Déclaration de conflit d'intérêts

Declaration of conflicting interestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Auteurs

Fadi Abu Baker (F)

Department of Gastroenterology and Hepatology, Hillel Yaffe medical center, Hadera, Israel.
Technion Faculty of Medicine, Haifa, Israel.

Ahmad Samhat (A)

Technion Faculty of Medicine, Haifa, Israel.
Department of internal medicine, Hillel Yaffe medical center, Hadera, Israel.

Randa Taher Natour (R)

Technion Faculty of Medicine, Haifa, Israel.
Department of internal medicine, Hillel Yaffe medical center, Hadera, Israel.

Abdel-Rauf Zeina (AR)

Technion Faculty of Medicine, Haifa, Israel.
Department of Radiology, Hillel Yaffe medical center, Hadera, Israel.

Yael Kopelman (Y)

Department of Gastroenterology and Hepatology, Hillel Yaffe medical center, Hadera, Israel.
Technion Faculty of Medicine, Haifa, Israel.

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Classifications MeSH