A comparative analysis of aerosol exposure and prevention strategies in bystander, pre-hospital, and inpatient cardiopulmonary resuscitation using simulation manikins.


Journal

Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288

Informations de publication

Date de publication:
02 08 2023
Historique:
received: 22 03 2023
accepted: 30 07 2023
medline: 4 8 2023
pubmed: 3 8 2023
entrez: 2 8 2023
Statut: epublish

Résumé

To evaluate aerosol exposure risk and prevention strategies during bystander, pre-hospital, and inpatient cardiopulmonary resuscitation (CPR). This study compared hands-only CPR, CPR with a surgical or N95 mask, and CPR with a non-rebreather mask at 15 L/min. 30:2 compression-ventilation ratio CPR was tested with face-mask ventilation (FMV), FMV with a high efficiency particulate air (HEPA) filter; supraglottic airway (SGA), SGA with a surgical mask, SGA with a HEPA filter, or SGA with both. Continuous CPR was tested with an endotracheal tube (ET), ET with a surgical mask, a HEPA filter, or both. Aerosol concentration at the head, trunk, and feet of the mannequin were measured to evaluate exposure to CPR personnel. Hands-only CPR with a surgical or N95 face mask coverings and ET tube ventilation CPR with filters showed the lowest aerosol exposure among all study groups, including CPR with NRM oxygenation, FMV, and SGA ventilation. NRM had a mask effect and reduced aerosol exposure at the head, trunk, and feet of the mannequin. FMV with filters during 30:2 CPR reduced aerosol exposure at the head and trunk, but increased at the feet of the mannequin. A tightly-sealed SGA when used with a HEPA filter, reduced aerosol exposure by 21.00-63.14% compared with a loose-fitting one. Hands-only CPR with a proper fit surgical or N95 face mask coverings is as safe as ET tube ventilation CPR with filters, compared with CPR with NRM, FMV, and SGA. FMV or tight-sealed SGA ventilation with filters prolonged the duration to achieve estimated infective dose of SARS-CoV-2 2.4-2.5 times longer than hands-on CPR only. However, a loose-fitting SGA is not protective at all to chest compressor or health workers standing at the foot side of the victim, so should be used with caution even when using with HEPA filters.

Identifiants

pubmed: 37532861
doi: 10.1038/s41598-023-39726-x
pii: 10.1038/s41598-023-39726-x
pmc: PMC10397338
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

12552

Informations de copyright

© 2023. The Author(s).

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Auteurs

Tzu-Yao Hung (TY)

Department of Emergency Medicine, Zhong-Xing Branch, Taipei City Hospital, Taipei City, Taiwan.
School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.
CrazyatLAB (Critical Airway Training Laboratory), Taipei City, Taiwan.

Chung-Shiung Wen (CS)

Department of Emergency Medicine, Zhong-Xing Branch, Taipei City Hospital, Taipei City, Taiwan.

Sheng-Han Yu (SH)

Department of Emergency Medicine, Zhong-Xing Branch, Taipei City Hospital, Taipei City, Taiwan.

Yi-Chang Chen (YC)

Department of Energy and Refrigerating Air-Conditioning Engineering, National Taipei University of Technology, Taipei, Taiwan.

Hsin-Ling Chen (HL)

Department of Emergency Medicine, Zhong-Xing Branch, Taipei City Hospital, Taipei City, Taiwan.

Wei-Lun Chen (WL)

Department of Emergency Medicine, Zhong-Xing Branch, Taipei City Hospital, Taipei City, Taiwan.

Chih-Chieh Wu (CC)

Department of Emergency Medicine, Zhong-Xing Branch, Taipei City Hospital, Taipei City, Taiwan.

Yung-Cheng Su (YC)

School of Medicine, Tzu Chi University, Hualien County, Taiwan. drsu119@gmail.com.
Department of Emergency Medicine, Ditmanson Medical Foundation Chiayi Christian Hospital, No.539, Zhongxiao Rd., East Dist., Chiayi City, 600566, Taiwan. drsu119@gmail.com.

Chun-Lung Lin (CL)

Department of Emergency Medicine, Zhong-Xing Branch, Taipei City Hospital, Taipei City, Taiwan.

Shih-Cheng Hu (SC)

Department of Energy and Refrigerating Air-Conditioning Engineering, National Taipei University of Technology, Taipei, Taiwan.

Tee Lin (T)

Department of Energy and Refrigerating Air-Conditioning Engineering, National Taipei University of Technology, Taipei, Taiwan.

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