A water-soluble fluorescent organic nano-photosensitizer for the ratiometric detection of mitochondrial G-quadruplexes with photodynamic therapy potential.

Photosensitizing Agents / pharmacology G-Quadruplexes Water Coloring Agents Photochemotherapy Fluorescent Dyes

Journal

Chemical communications (Cambridge, England)
ISSN: 1364-548X
Titre abrégé: Chem Commun (Camb)
Pays: England
ID NLM: 9610838

Informations de publication

Date de publication:
22 Aug 2023
Historique:
medline: 23 8 2023
pubmed: 4 8 2023
entrez: 4 8 2023
Statut: epublish

Résumé

We report a water-soluble AIEgen (TPAL) that can self-assemble into fluorescent organic nanoparticles for the ratiometric detection of mitochondrial DNA (mtDNA) parallel G-quadruplexes (G4s) with high selectivity, a low detection limit and photodynamic therapy (PDT) potential.

Identifiants

DOI: 10.1039/d3cc02788k PMID: 37539814
pubmed: 37539814
doi: 10.1039/d3cc02788k
doi:

Substances chimiques

Photosensitizing Agents 0
Water 059QF0KO0R
Coloring Agents 0
Fluorescent Dyes 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

10287-10290

Auteurs

Qing-Yu Ma (QY)

College of Chemistry, Beijing Normal University, Beijing, 100875, China. yuanzhang@bnu.edu.cn.

Xiang Li (X)

College of Chemistry, Beijing Normal University, Beijing, 100875, China. yuanzhang@bnu.edu.cn.

Wei Zhou (W)

College of Chemistry, Beijing Normal University, Beijing, 100875, China. yuanzhang@bnu.edu.cn.

Xia-Fen Li (XF)

College of Chemistry, Beijing Normal University, Beijing, 100875, China. yuanzhang@bnu.edu.cn.

Yi-Chen Liu (YC)

College of Chemistry, Beijing Normal University, Beijing, 100875, China. yuanzhang@bnu.edu.cn.

Gai-Li Feng (GL)

College of Chemistry, Beijing Normal University, Beijing, 100875, China. yuanzhang@bnu.edu.cn.

Hongwei Tan (H)

College of Chemistry, Beijing Normal University, Beijing, 100875, China. yuanzhang@bnu.edu.cn.
ORCID: 0000-0002-1376-6019

Yuan Zhang (Y)

College of Chemistry, Beijing Normal University, Beijing, 100875, China. yuanzhang@bnu.edu.cn.
Key Laboratory of Energy Conversion and Storage Materials, College of Chemistry, Beijing Normal University, Beijing, 100875, China.

Guo-Wen Xing (GW)

College of Chemistry, Beijing Normal University, Beijing, 100875, China. yuanzhang@bnu.edu.cn.
ORCID: 0000-0001-8766-7569

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Classifications MeSH

questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Radiosensibilisants › Photosensibilisants › A water-soluble fluorescent organic...
questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Conformation d'acide nucléique › G-quadruplexes › A water-soluble fluorescent organic...
questionsmedicales.fr › Produits chimiques inorganiques › Composés de l'oxygène › Oxydes › Eau › A water-soluble fluorescent organic...
questionsmedicales.fr › Actions chimiques et utilisations › Utilisations spécialisées de produits chimiques › Agents colorants › A water-soluble fluorescent organic...
questionsmedicales.fr › Thérapeutique › Photothérapie › Photothérapie dynamique › A water-soluble fluorescent organic...
questionsmedicales.fr › Actions chimiques et utilisations › Utilisations spécialisées de produits chimiques › Produits chimiques de laboratoire › Indicateurs et réactifs › Luminescents › Colorants fluorescents › A water-soluble fluorescent organic...