Proteome changes of fibroblasts and endothelial cells upon incubation with human cytomegalovirus subviral Dense Bodies.


Journal

Scientific data
ISSN: 2052-4463
Titre abrégé: Sci Data
Pays: England
ID NLM: 101640192

Informations de publication

Date de publication:
04 08 2023
Historique:
received: 19 01 2023
accepted: 25 07 2023
medline: 7 8 2023
pubmed: 5 8 2023
entrez: 4 8 2023
Statut: epublish

Résumé

Human cytomegalovirus (HCMV) is a pathogen of high medical relevance. Subviral Dense Bodies (DB) were developed as a vaccine candidate to ameliorate the severe consequences of HCMV infection. Development of such a candidate vaccine for human application requires detailed knowledge of its interaction with the host. A comprehensive mass spectrometry (MS)- based analysis was performed regarding the changes in the proteome of cell culture cells, exposed to DB.

Identifiants

pubmed: 37542058
doi: 10.1038/s41597-023-02418-2
pii: 10.1038/s41597-023-02418-2
pmc: PMC10403606
doi:

Substances chimiques

Proteome 0

Types de publication

Dataset Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

517

Subventions

Organisme : Wilhelm Sander-Stiftung (Wilhelm Sander Foundation)
ID : 2016.115.1 and 2020.003.1.

Informations de copyright

© 2023. Springer Nature Limited.

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Auteurs

Inessa Penner (I)

Institute for Virology, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany.

Mario Dejung (M)

Institute of Molecular Biology, Johannes Gutenberg-University, Mainz, Germany.

Anja Freiwald (A)

Institute of Molecular Biology, Johannes Gutenberg-University, Mainz, Germany.

Falk Butter (F)

Institute of Molecular Biology, Johannes Gutenberg-University, Mainz, Germany.

Jia-Xuan Chen (JX)

Institute of Molecular Biology, Johannes Gutenberg-University, Mainz, Germany.

Bodo Plachter (B)

Institute for Virology, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany. plachter@uni-mainz.de.

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Classifications MeSH