Discovery of novel salicylaldehyde derivatives incorporating an α-methylene-γ-butyrolactone moiety as fungicidal agents.
fungicidal activity
mode of action
natural products
salicylaldehyde
α-methylene-γ-butyrolactone
Journal
Pest management science
ISSN: 1526-4998
Titre abrégé: Pest Manag Sci
Pays: England
ID NLM: 100898744
Informations de publication
Date de publication:
Dec 2023
Dec 2023
Historique:
revised:
20
07
2023
received:
05
05
2023
accepted:
03
08
2023
medline:
16
11
2023
pubmed:
7
8
2023
entrez:
6
8
2023
Statut:
ppublish
Résumé
Plant diseases caused by phytopathogenic fungi and oomycetes pose a serious threat to ensuring crop yield and quality. Finding novel fungicidal candidates based on natural products is one of the critical methods for developing effective and environmentally friendly pesticides. In this study, a series of salicylaldehyde derivatives containing an α-methylene-γ-butyrolactone moiety were designed, synthesized, and their fungicidal activities were evaluated. The bioassay studies indicated that compound C3 displayed an excellent in vitro activity against Rhizoctonia solani with a half-maximal effective concentration (EC The present study provides support for the application of these salicylaldehyde derivatives as promising potential pesticides with remarkable and broad-spectrum fungicidal activities against phytopathogenic fungi and oomycetes in crop protection. © 2023 Society of Chemical Industry.
Sections du résumé
BACKGROUND
BACKGROUND
Plant diseases caused by phytopathogenic fungi and oomycetes pose a serious threat to ensuring crop yield and quality. Finding novel fungicidal candidates based on natural products is one of the critical methods for developing effective and environmentally friendly pesticides. In this study, a series of salicylaldehyde derivatives containing an α-methylene-γ-butyrolactone moiety were designed, synthesized, and their fungicidal activities were evaluated.
RESULTS
RESULTS
The bioassay studies indicated that compound C3 displayed an excellent in vitro activity against Rhizoctonia solani with a half-maximal effective concentration (EC
CONCLUSION
CONCLUSIONS
The present study provides support for the application of these salicylaldehyde derivatives as promising potential pesticides with remarkable and broad-spectrum fungicidal activities against phytopathogenic fungi and oomycetes in crop protection. © 2023 Society of Chemical Industry.
Substances chimiques
pyrachlostrobin
DJW8M9OX1H
salicylaldehyde
17K64GZH20
alpha-methylene gamma-butyrolactone
362Y256BOL
Fungicides, Industrial
0
Antifungal Agents
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
5015-5028Subventions
Organisme : Chinese Universities Scientific Fund
ID : 2452019189
Organisme : Chinese Universities Scientific Fund
ID : 2452018318
Organisme : Program for Science & Technology Innovation Team of Shaanxi Province
ID : 2020TD-035
Organisme : National Undergraduate Training Program for Innovation and Entrepreneurship
ID : 202210712073
Organisme : National Natural Science Foundation of China
ID : 32202355
Informations de copyright
© 2023 Society of Chemical Industry.
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