Purple Yam Polyphenol Extracts Exert Anticolitis and Anticolitis-Associated Colorectal Cancer Effects through Inactivation of NF-κB/p65 and STAT3 Signaling Pathways.

Animals Mice NF-kappa B / genetics Dioscorea / metabolism Polyphenols / pharmacology Signal Transduction Colitis / chemically induced Colitis, Ulcerative Anti-Inflammatory Agents / pharmacology Colorectal Neoplasms / metabolism Dextran Sulfate / adverse effects Disease Models, Animal Mice, Inbred C57BL
NF-κB STAT3 colitis colitis-associated colorectal cancer purple yam polyphenol extracts

Journal

Journal of agricultural and food chemistry
ISSN: 1520-5118
Titre abrégé: J Agric Food Chem
Pays: United States
ID NLM: 0374755

Informations de publication

Date de publication:
16 Aug 2023
Historique:
medline: 17 8 2023
pubmed: 7 8 2023
entrez: 7 8 2023
Statut: ppublish

Résumé

Colorectal cancer is a malignancy with high incidence and mortality worldwide, and ulcerative colitis (UC) is strongly associated with colorectal cancer. Purple yam, also known as

Identifiants

DOI: 10.1021/acs.jafc.3c00346 PMID: 37545095
pubmed: 37545095
doi: 10.1021/acs.jafc.3c00346
doi:

Substances chimiques

NF-kappa B 0
Polyphenols 0
Anti-Inflammatory Agents 0
Dextran Sulfate 9042-14-2

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

12177-12189

Auteurs

Xinyue Yang (X)

Key Laboratory of Human Genetics and Environmental Medicine, School of Public Health, Xuzhou Medical University, Xuzhou, Jiangsu 221004, People's Republic of China.
Key Lab of Environment and Health, School of Public Health, Xuzhou Medical University, Xuzhou, Jiangsu 221004, People's Republic of China.

Qing Wang (Q)

Key Laboratory of Human Genetics and Environmental Medicine, School of Public Health, Xuzhou Medical University, Xuzhou, Jiangsu 221004, People's Republic of China.
Key Lab of Environment and Health, School of Public Health, Xuzhou Medical University, Xuzhou, Jiangsu 221004, People's Republic of China.

Xinghai Zhang (X)

Key Laboratory of Human Genetics and Environmental Medicine, School of Public Health, Xuzhou Medical University, Xuzhou, Jiangsu 221004, People's Republic of China.
Key Lab of Environment and Health, School of Public Health, Xuzhou Medical University, Xuzhou, Jiangsu 221004, People's Republic of China.

Lingling Li (L)

Key Laboratory of Human Genetics and Environmental Medicine, School of Public Health, Xuzhou Medical University, Xuzhou, Jiangsu 221004, People's Republic of China.
Key Lab of Environment and Health, School of Public Health, Xuzhou Medical University, Xuzhou, Jiangsu 221004, People's Republic of China.

Xingyue Cao (X)

Key Laboratory of Human Genetics and Environmental Medicine, School of Public Health, Xuzhou Medical University, Xuzhou, Jiangsu 221004, People's Republic of China.
Key Lab of Environment and Health, School of Public Health, Xuzhou Medical University, Xuzhou, Jiangsu 221004, People's Republic of China.

Li Zhou (L)

Key Laboratory of Human Genetics and Environmental Medicine, School of Public Health, Xuzhou Medical University, Xuzhou, Jiangsu 221004, People's Republic of China.
Key Lab of Environment and Health, School of Public Health, Xuzhou Medical University, Xuzhou, Jiangsu 221004, People's Republic of China.

Yefei Huang (Y)

Key Laboratory of Human Genetics and Environmental Medicine, School of Public Health, Xuzhou Medical University, Xuzhou, Jiangsu 221004, People's Republic of China.
Key Lab of Environment and Health, School of Public Health, Xuzhou Medical University, Xuzhou, Jiangsu 221004, People's Republic of China.

Guixiang Sun (G)

Key Laboratory of Human Genetics and Environmental Medicine, School of Public Health, Xuzhou Medical University, Xuzhou, Jiangsu 221004, People's Republic of China.
Key Lab of Environment and Health, School of Public Health, Xuzhou Medical University, Xuzhou, Jiangsu 221004, People's Republic of China.

Yansu Chen (Y)

Key Laboratory of Human Genetics and Environmental Medicine, School of Public Health, Xuzhou Medical University, Xuzhou, Jiangsu 221004, People's Republic of China.
Key Lab of Environment and Health, School of Public Health, Xuzhou Medical University, Xuzhou, Jiangsu 221004, People's Republic of China.
ORCID: 0000-0001-6625-0908

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Purple Yam Polyphenol Extracts Exert...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Purple Yam Polyphenol Extracts Exert...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Facteurs de transcription › Facteur de transcription NF-kappa B › Purple Yam Polyphenol Extracts Exert...
questionsmedicales.fr › Eucaryotes › Viridiplantae › Streptophyta › Embryophyta › Tracheobionta › Magnoliopsida › Dioscoreaceae › Dioscorea › Purple Yam Polyphenol Extracts Exert...
questionsmedicales.fr › Composés chimiques organiques › Hydrocarbures › Hydrocarbures cycliques › Hydrocarbures aromatiques › Dérivés du benzène › Phénols › Polyphénols › Purple Yam Polyphenol Extracts Exert...
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Transduction du signal › Purple Yam Polyphenol Extracts Exert...
questionsmedicales.fr › Maladies de l'appareil digestif › Maladies gastro-intestinales › Maladies intestinales › Maladies du côlon › Colite › Purple Yam Polyphenol Extracts Exert...
questionsmedicales.fr › Maladies de l'appareil digestif › Maladies gastro-intestinales › Maladies intestinales › Maladies inflammatoires intestinales › Rectocolite hémorragique › Purple Yam Polyphenol Extracts Exert...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Anti-inflammatoires › Purple Yam Polyphenol Extracts Exert...
questionsmedicales.fr › Maladies de l'appareil digestif › Maladies gastro-intestinales › Maladies intestinales › Maladies du rectum › Tumeurs colorectales › Purple Yam Polyphenol Extracts Exert...
questionsmedicales.fr › Glucides › Polyosides › Glucanes › Dextrane › Sulfate dextran › Purple Yam Polyphenol Extracts Exert...
questionsmedicales.fr › Techniques d'investigation › Modèles théoriques › Modèles biologiques › Modèles animaux de maladie humaine › Purple Yam Polyphenol Extracts Exert...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Lignées consanguines de souris › Souris de lignée C57BL › Purple Yam Polyphenol Extracts Exert...