Coverage survey of typhoid conjugate vaccine among children aged 6 months to 15 years in an urban slum settlement of Lyari Town Karachi, Pakistan.


Journal

PloS one
ISSN: 1932-6203
Titre abrégé: PLoS One
Pays: United States
ID NLM: 101285081

Informations de publication

Date de publication:
2023
Historique:
received: 13 07 2021
accepted: 24 07 2023
medline: 9 8 2023
pubmed: 7 8 2023
entrez: 7 8 2023
Statut: epublish

Résumé

To estimate the coverage rate of typhoid conjugate vaccine (TCV) among children aged 6 months to 15 years in Lyari Town Karachi, Pakistan. A cross-sectional survey was conducted to estimate the vaccine coverage of Typbar TCV in Lyari Town Karachi utilizing the World Health Organization (WHO) recommended rapid vaccine coverage assessment technique (30 clusters × 7 households). Sampling was powered at town level and multistage cluster sampling was used. Four union councils were randomly selected from a total of 11 and the survey was conducted in those union councils. After consent was obtained, parents of age-eligible children living in the selected union councils were invited to participate in the survey and information was collected on Typbar TCV vaccination status of children aged 6 months to 15 years. Overall, 2325 children were included in the survey. The mean age of the participants was 7.60 ± 3.84 years. The ratio of males to females was equal in the survey sample; 1163 (50.02%) were male. In the total target population, 82% children were found to be vaccinated; however, the vaccination status could be verified for 80%. The vaccine coverage of TCV was comparable among the four union councils and the overall coverage of TCV vaccine in Lyari Town was found to be 80%. The coverage was significantly lower in younger children, 5% and 17% among children aged 6 months to < 2 years and 2 years to < 5 years respectively and 78% among children aged 5 years to 15 years. The overall immunization coverage rate with TCV was found to be satisfactory. Immunization coverage was comparable among both sexes and the selected union councils but it was relatively low among children in younger age groups.

Identifiants

pubmed: 37549155
doi: 10.1371/journal.pone.0289582
pii: PONE-D-21-22790
pmc: PMC10406246
doi:

Substances chimiques

Vaccines, Conjugate 0
Typhoid-Paratyphoid Vaccines 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e0289582

Informations de copyright

Copyright: © 2023 Batool et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Déclaration de conflit d'intérêts

The authors have declared that no competing interests exist.

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Auteurs

Rabab Batool (R)

Department of Pediatrics and Child Health, Aga Khan University Hospital, Karachi, Pakistan.
Center for Child, Adolescent, and Maternal Health, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.

Sonia Qureshi (S)

Department of Pediatrics and Child Health, Aga Khan University Hospital, Karachi, Pakistan.

Zoya Haq (Z)

Liaqat National Hospital, Karachi, Pakistan.

Mohammad Tahir Yousafzai (MT)

Department of Pediatrics and Child Health, Aga Khan University Hospital, Karachi, Pakistan.
Kirby Institute, University of New South Wales, Sydney, NSW, Australia.

Rehana A Salam (RA)

Department of Pediatrics and Child Health, Aga Khan University Hospital, Karachi, Pakistan.

Rafey Ali (R)

Department of Pediatrics and Child Health, Aga Khan University Hospital, Karachi, Pakistan.

Tahira Sadaf (T)

Department of Pediatrics and Child Health, Aga Khan University Hospital, Karachi, Pakistan.

Miqdad Ali (M)

Department of Pediatrics and Child Health, Aga Khan University Hospital, Karachi, Pakistan.

Farah Naz Qamar (FN)

Department of Pediatrics and Child Health, Aga Khan University Hospital, Karachi, Pakistan.

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