NET histones inflame periodontitis.
Journal
The Journal of experimental medicine
ISSN: 1540-9538
Titre abrégé: J Exp Med
Pays: United States
ID NLM: 2985109R
Informations de publication
Date de publication:
04 09 2023
04 09 2023
Historique:
pmc-release:
08
02
2024
medline:
9
8
2023
pubmed:
8
8
2023
entrez:
8
8
2023
Statut:
ppublish
Résumé
Microbial dysbiosis triggers inflammatory periodontitis. In this issue of JEM, Kim et al. (2023. J. Exp. Med.https://doi.org/10.1084/jem.20221751) demonstrate that neutrophil extracellular trap histones are the major mediators fueling the pathogenic Th17 inflammation that promotes gum and bone loss in periodontitis.
Identifiants
pubmed: 37552469
pii: 276160
doi: 10.1084/jem.20230783
pmc: PMC10407781
pii:
doi:
Substances chimiques
Histones
0
Types de publication
Journal Article
Comment
Langues
eng
Sous-ensembles de citation
IM
Commentaires et corrections
Type : CommentOn
Informations de copyright
© 2023 Papayannopoulos.
Références
Front Immunol. 2022 Jul 07;13:915081
pubmed: 35874771
Cell Host Microbe. 2019 Apr 10;25(4):526-536.e4
pubmed: 30930127
Cell Rep. 2020 May 5;31(5):107602
pubmed: 32375035
Nat Rev Immunol. 2018 Feb;18(2):134-147
pubmed: 28990587
Int J Med Microbiol. 2015 Jun-Aug;305(4-5):453-63
pubmed: 25959370