Turn-on fluorescence of ruthenium pyrene complexes in response to bovine serum albumin.

Serum Albumin, Bovine / chemistry Ruthenium / chemistry Serum Albumin Spectrometry, Fluorescence Pyrenes

Journal

Dalton transactions (Cambridge, England : 2003)
ISSN: 1477-9234
Titre abrégé: Dalton Trans
Pays: England
ID NLM: 101176026

Informations de publication

Date de publication:
22 Aug 2023
Historique:
medline: 23 8 2023
pubmed: 9 8 2023
entrez: 9 8 2023
Statut: epublish

Résumé

Two novel pyrene triphenylphosphine ruthenium conjugates act as fluorescent turn-on beacons for serum albumin, being non-fluorescent in aqueous media but exhibiting strong emission upon binding to BSA. The selective cytotoxicity of the compounds against tumour cells is enhanced upon irradiation by UV-light, paving the way for application in photodynamic therapy under two-photon excitation.

Identifiants

DOI: 10.1039/d3dt02289g PMID: 37555301
pubmed: 37555301
doi: 10.1039/d3dt02289g
doi:

Substances chimiques

Serum Albumin, Bovine 27432CM55Q
Ruthenium 7UI0TKC3U5
Serum Albumin 0
Pyrenes 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

11698-11704

Auteurs

Saša Opačak (S)

Ruđer Boškovic Institute, Bijenička cesta 54, HR-10000 Zagreb, Croatia. Srecko.Kirin@irb.hr.
ORCID: 0000-0002-6110-0801

Margareta Pernar Kovač (M)

Ruđer Boškovic Institute, Bijenička cesta 54, HR-10000 Zagreb, Croatia. Srecko.Kirin@irb.hr.
ORCID: 0000-0001-9737-6095

Anamaria Brozovic (A)

Ruđer Boškovic Institute, Bijenička cesta 54, HR-10000 Zagreb, Croatia. Srecko.Kirin@irb.hr.

Ivo Piantanida (I)

Ruđer Boškovic Institute, Bijenička cesta 54, HR-10000 Zagreb, Croatia. Srecko.Kirin@irb.hr.

Srećko I Kirin (SI)

Ruđer Boškovic Institute, Bijenička cesta 54, HR-10000 Zagreb, Croatia. Srecko.Kirin@irb.hr.
ORCID: 0000-0002-0500-2422

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Classifications MeSH

questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines du sang › Sérumalbumine › Sérumalbumine bovine › Turn-on fluorescence of ruthenium pyrene...
questionsmedicales.fr › Produits chimiques inorganiques › Métaux › Métaux lourds › Ruthénium › Turn-on fluorescence of ruthenium pyrene...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines du sang › Sérumalbumine › Turn-on fluorescence of ruthenium pyrene...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Analyse spectrale › Spectrométrie de fluorescence › Turn-on fluorescence of ruthenium pyrene...
questionsmedicales.fr › Composés polycycliques › Hydrocarbures aromatiques polycycliques › Pyrènes › Turn-on fluorescence of ruthenium pyrene...