A primary amoebic meningoencephalitis case associated with swimming in seawater.
Naegleria fowleri
Primary amebic meningoencephalitis
Journal
Parasitology research
ISSN: 1432-1955
Titre abrégé: Parasitol Res
Pays: Germany
ID NLM: 8703571
Informations de publication
Date de publication:
Oct 2023
Oct 2023
Historique:
received:
18
06
2023
accepted:
01
08
2023
medline:
12
9
2023
pubmed:
9
8
2023
entrez:
9
8
2023
Statut:
ppublish
Résumé
This case report describes a 62-year-old male fisherman who presented with persistent vomiting, headache, and behavior changes. Despite initial antibiotic and corticosteroid treatment, his condition worsened, leading to coma and subsequent death. Macro-genome sequencing of cerebrospinal fluid (CSF) revealed the presence of Naegleria fowleri infection, which had been missed during initial laboratory tests. The patient's exposure history included sea-swimming near Zhoushan Island.
Identifiants
pubmed: 37555856
doi: 10.1007/s00436-023-07934-z
pii: 10.1007/s00436-023-07934-z
doi:
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
2451-2452Informations de copyright
© 2023. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.
Références
Carter RF (1968) Primary amoebic meningo-encephalitis: clinical, pathological and epidemiological features of six fatal cases. J Pathol Bacteriol 96(1):1–25. https://doi.org/10.1002/path.1700960102
doi: 10.1002/path.1700960102
pubmed: 5667848
Heggie TW, Küpper T (2017) Surviving Naegleria fowleri infections: a successful case report and novel therapeutic approach. Travel Med Infect Dis 16:49–51. https://doi.org/10.1016/j.tmaid.2016.12.005
doi: 10.1016/j.tmaid.2016.12.005
pubmed: 28013053
Martínez DY, Bravo-Cossio F, Valdivia-Tapia MDC, Carreazo NY, Cabello-Vilchez AM (2022) Successful treatment of primary amoebic meningoencephalitis using a novel therapeutic regimen including miltefosine and voriconazole. Acta Parasitol 67(3):1421–1424. https://doi.org/10.1007/s11686-022-00591-9
doi: 10.1007/s11686-022-00591-9
pubmed: 35861895
Monogue ML et al (2019) Minimal cerebrospinal fluid concentration of miltefosine despite therapeutic plasma levels during the treatment of amebic encephalitis. Antimicrob Agents Chemother 64(1):10–1128. https://doi.org/10.1128/aac.01127-19
doi: 10.1128/aac.01127-19
Phu NH et al (2013) Fatal consequences of freshwater pearl diving. Lancet (London, England) 381(9861):176. https://doi.org/10.1016/s0140-6736(12)61730-9
doi: 10.1016/s0140-6736(12)61730-9
pubmed: 23312755
Zhang LL et al (2018) Identification and molecular typing of Naegleria fowleri from a patient with primary amebic meningoencephalitis in China. Int J Infect Dis 72:28–33. https://doi.org/10.1016/j.ijid.2018.05.001
doi: 10.1016/j.ijid.2018.05.001
pubmed: 29751112