Natural Products from Singapore Soil-Derived
Staphylococcus aureus
Streptomycetaceae
actinobacteria
antimicrobial
natural products
tetronomycin
Journal
Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009
Informations de publication
Date de publication:
02 Aug 2023
02 Aug 2023
Historique:
received:
28
06
2023
revised:
26
07
2023
accepted:
26
07
2023
medline:
14
8
2023
pubmed:
12
8
2023
entrez:
12
8
2023
Statut:
epublish
Résumé
Natural products have long been used as a source of antimicrobial agents against various microorganisms. Actinobacteria are a group of bacteria best known to produce a wide variety of bioactive secondary metabolites, including many antimicrobial agents. In this study, four actinobacterial strains found in Singapore terrestrial soil were investigated as potential sources of new antimicrobial compounds. Large-scale cultivation, chemical, and biological investigation led to the isolation of a previously undescribed tetronomycin A (
Identifiants
pubmed: 37570802
pii: molecules28155832
doi: 10.3390/molecules28155832
pmc: PMC10421265
pii:
doi:
Substances chimiques
Biological Products
0
tetronomycin
82206-10-8
Anti-Bacterial Agents
0
Anti-Infective Agents
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Natural Product Research Laboratory Biomedical Research Council of A*STAR (Agency for Science, Technology and Research) Transition Fund
ID : H16/99/b0/004
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