Center-level factors associated with shorter length of stay following stage 1 palliation: An analysis of the national pediatric cardiology quality improvement collaborative registry.


Journal

American heart journal
ISSN: 1097-6744
Titre abrégé: Am Heart J
Pays: United States
ID NLM: 0370465

Informations de publication

Date de publication:
11 2023
Historique:
received: 07 06 2023
revised: 24 07 2023
accepted: 05 08 2023
medline: 23 10 2023
pubmed: 13 8 2023
entrez: 12 8 2023
Statut: ppublish

Résumé

Stage 1 single ventricle palliation (S1P) has the longest length of stay (LOS) of all benchmark congenital heart operations. Center-level factors contributing to prolonged hospitalization are poorly defined. We analyzed data from infants status post S1P included in the National Pediatric Cardiology Quality Improvement Collaborative Phase II registry. Our primary outcome was patient-level LOS with days alive and out of hospital before stage 2 palliation (S2P) used as a balancing measure. We compared patient and center-level characteristics across quartiles for median center LOS, and used multivariable regression to calculate center-level factors associated with LOS after adjusting for case mix. Of 2,510 infants (65 sites), 2037 (47 sites) met study criteria (61% male, 61% white, 72% hypoplastic left heart syndrome). There was wide intercenter variation in LOS (first quartile centers: median 28 days [IQR 19, 46]; fourth quartile: 62 days [35, 95], P < .001). Mortality prior to S2P did not differ across quartiles. Shorter LOS correlated with more pre-S2P days alive and out of hospital, after accounting for readmissions (correlation coefficient -0.48, P < .001). In multivariable analysis, increased use of Norwood with a right ventricle to pulmonary artery conduit (aOR 2.65 [1.1, 6.37]), shorter bypass time (aOR 0.99 per minute [0.98,1.0]), fewer additional cardiac operations (aOR 0.46 [0.22, 0.93]), and increased use of NG tubes rather than G tubes (aOR 7.03 [1.95, 25.42]) were all associated with shorter LOS centers. Modifiable center-level practices may be targets to standardize practice and reduce overall LOS across centers.

Sections du résumé

BACKGROUND
Stage 1 single ventricle palliation (S1P) has the longest length of stay (LOS) of all benchmark congenital heart operations. Center-level factors contributing to prolonged hospitalization are poorly defined.
METHODS
We analyzed data from infants status post S1P included in the National Pediatric Cardiology Quality Improvement Collaborative Phase II registry. Our primary outcome was patient-level LOS with days alive and out of hospital before stage 2 palliation (S2P) used as a balancing measure. We compared patient and center-level characteristics across quartiles for median center LOS, and used multivariable regression to calculate center-level factors associated with LOS after adjusting for case mix.
RESULTS
Of 2,510 infants (65 sites), 2037 (47 sites) met study criteria (61% male, 61% white, 72% hypoplastic left heart syndrome). There was wide intercenter variation in LOS (first quartile centers: median 28 days [IQR 19, 46]; fourth quartile: 62 days [35, 95], P < .001). Mortality prior to S2P did not differ across quartiles. Shorter LOS correlated with more pre-S2P days alive and out of hospital, after accounting for readmissions (correlation coefficient -0.48, P < .001). In multivariable analysis, increased use of Norwood with a right ventricle to pulmonary artery conduit (aOR 2.65 [1.1, 6.37]), shorter bypass time (aOR 0.99 per minute [0.98,1.0]), fewer additional cardiac operations (aOR 0.46 [0.22, 0.93]), and increased use of NG tubes rather than G tubes (aOR 7.03 [1.95, 25.42]) were all associated with shorter LOS centers.
CONCLUSIONS
Modifiable center-level practices may be targets to standardize practice and reduce overall LOS across centers.

Identifiants

pubmed: 37572784
pii: S0002-8703(23)00200-4
doi: 10.1016/j.ahj.2023.08.003
pii:
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

143-152

Subventions

Organisme : NICHD NIH HHS
ID : T32 HD094671
Pays : United States

Informations de copyright

Copyright © 2023 Elsevier Inc. All rights reserved.

Auteurs

Henry P Foote (HP)

Division of Pediatric Cardiology, Duke University Medical Center, Durham, NC.

Dylan Thibault (D)

Duke Clinical Research Institute, Durham, NC.

Carla Dominguez Gonzalez (CD)

Duke University School of Medicine, Durham, NC.

Garick D Hill (GD)

Division of Cardiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.

L Luann Minich (LL)

Department of Pediatrics, The University of Utah and Primary Children's Hospital, Salt Lake City, UT.

Douglas M Overbey (DM)

Division of Cardiothoracic Surgery, Duke University Medical Center, Durham, NC.

Sarah L Tallent (SL)

Division of Pediatric Cardiology, Duke University Medical Center, Durham, NC.

Kevin D Hill (KD)

Division of Pediatric Cardiology, Duke University Medical Center, Durham, NC; Duke Clinical Research Institute, Durham, NC. Electronic address: kevin.hill@duke.edu.

Andrew W McCrary (AW)

Division of Pediatric Cardiology, Duke University Medical Center, Durham, NC.

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