The efficacy of apneic oxygenation during intubation using a prototype of an oxygenation laryngoscope - a technical simulation.


Journal

BMC anesthesiology
ISSN: 1471-2253
Titre abrégé: BMC Anesthesiol
Pays: England
ID NLM: 100968535

Informations de publication

Date de publication:
14 08 2023
Historique:
received: 31 03 2023
accepted: 04 08 2023
medline: 16 8 2023
pubmed: 15 8 2023
entrez: 14 8 2023
Statut: epublish

Résumé

Recently, a non-commercial oxygenation laryngoscope was able to maintain apneic oxygenation during simulated intubation efforts. Since that prototype was 3 mm wider than a standard Macintosh laryngoscope blade, the intubation performance of this device may differ from standard blades. A new prototype of an oxygenation laryngoscope was developed, consisting of a standard-size Macintosh blade and a fixed oxygen supply line to the side. Actually, it is unclear at which point of this blade the oxygen supply line should end to facilitate the best possible oxygen supply for apneic oxygenation. In this simulation study using a standardized human airway manikin, the efficacy of apneic oxygenation by oxygen insufflation using standard and modified Macintosh blades was compared: a standard Macintosh blade without oxygen supply line as control, one with an additional oxygen supply line ending proximal near the handle, one with the line ending at the middle of the blade, and one with the line ending near the tip. A preoxygenated test lung was connected to an oximeter with a flow rate of 200ml/min, simulating oxygen consumption of a male adult, and to the trachea of an anatomically correctly shaped airway manikin. Apneic oxygenation was performed and oxygen content was measured over a 20-minutes observation period. Experiments were repeated five times for each laryngoscope blade. Oxygen percentage in the test lung dropped from 100 ± 0% at the start of the experiment to 53 ± 1.5% in the room air control group (p < 0.001 compared to all other groups), and to 74 ± 2.5% in the proximal oxygen line group, whereas oxygen percentage remained at 100% in both the medium and distal oxygen line groups (p = 1 between these groups; p < 0.001 between all other groups). In this simulation study with a preoxygenated airway manikin, the use of a modified Macintosh laryngoscope blade with oxygen line attached at the tip or at the middle were able to maintain apneic oxygenation without measurable drop of oxygen content over 20 min. Proximal placement of the oxygen supply line still showed an advantage against room air, however it did not completely prevent room air from entering the airway. Not applicable.

Sections du résumé

BACKGROUND
Recently, a non-commercial oxygenation laryngoscope was able to maintain apneic oxygenation during simulated intubation efforts. Since that prototype was 3 mm wider than a standard Macintosh laryngoscope blade, the intubation performance of this device may differ from standard blades. A new prototype of an oxygenation laryngoscope was developed, consisting of a standard-size Macintosh blade and a fixed oxygen supply line to the side. Actually, it is unclear at which point of this blade the oxygen supply line should end to facilitate the best possible oxygen supply for apneic oxygenation.
METHODS
In this simulation study using a standardized human airway manikin, the efficacy of apneic oxygenation by oxygen insufflation using standard and modified Macintosh blades was compared: a standard Macintosh blade without oxygen supply line as control, one with an additional oxygen supply line ending proximal near the handle, one with the line ending at the middle of the blade, and one with the line ending near the tip. A preoxygenated test lung was connected to an oximeter with a flow rate of 200ml/min, simulating oxygen consumption of a male adult, and to the trachea of an anatomically correctly shaped airway manikin. Apneic oxygenation was performed and oxygen content was measured over a 20-minutes observation period. Experiments were repeated five times for each laryngoscope blade.
RESULTS
Oxygen percentage in the test lung dropped from 100 ± 0% at the start of the experiment to 53 ± 1.5% in the room air control group (p < 0.001 compared to all other groups), and to 74 ± 2.5% in the proximal oxygen line group, whereas oxygen percentage remained at 100% in both the medium and distal oxygen line groups (p = 1 between these groups; p < 0.001 between all other groups).
CONCLUSIONS
In this simulation study with a preoxygenated airway manikin, the use of a modified Macintosh laryngoscope blade with oxygen line attached at the tip or at the middle were able to maintain apneic oxygenation without measurable drop of oxygen content over 20 min. Proximal placement of the oxygen supply line still showed an advantage against room air, however it did not completely prevent room air from entering the airway.
TRIAL REGISTRATION
Not applicable.

Identifiants

pubmed: 37580678
doi: 10.1186/s12871-023-02234-6
pii: 10.1186/s12871-023-02234-6
pmc: PMC10424410
doi:

Substances chimiques

Oxygen S88TT14065

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

273

Informations de copyright

© 2023. BioMed Central Ltd., part of Springer Nature.

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Auteurs

Wolfgang A Wetsch (WA)

Faculty of Medicine, University of Cologne, Albertus-Magnus-Platz 1, 50931, Cologne, Germany. wolfgang.wetsch@uk-koeln.de.
Department of Anaesthesiology and Intensive Care Medicine, University Hospital of Cologne, Cologne, Germany. wolfgang.wetsch@uk-koeln.de.

Daniel C Schroeder (DC)

Faculty of Medicine, University of Cologne, Albertus-Magnus-Platz 1, 50931, Cologne, Germany.
Department of Anaesthesiology and Intensive Care, German Armed Forces Central Hospital, Koblenz, Germany.

Susanne J Herff (SJ)

Faculty of Medicine, University of Cologne, Albertus-Magnus-Platz 1, 50931, Cologne, Germany.

Bernd W Böttiger (BW)

Faculty of Medicine, University of Cologne, Albertus-Magnus-Platz 1, 50931, Cologne, Germany.
Department of Anaesthesiology and Intensive Care Medicine, University Hospital of Cologne, Cologne, Germany.

Volker Wenzel (V)

Department of Anesthesiology, Friedrichshafen Regional Medical Center, Friedrichshafen, Germany.
Department of Anesthesiology, University of Florida, Gainesville, FL, USA.

Holger Herff (H)

Faculty of Medicine, University of Cologne, Albertus-Magnus-Platz 1, 50931, Cologne, Germany.
Department of Anaesthesiology and Intensive Care Medicine, University Hospital of Cologne, Cologne, Germany.
Department of Anesthesiology, PAN Clinic, Cologne, Germany.

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