Future prospects in mRNA vaccine development.


Journal

Biomedical materials (Bristol, England)
ISSN: 1748-605X
Titre abrégé: Biomed Mater
Pays: England
ID NLM: 101285195

Informations de publication

Date de publication:
17 08 2023
Historique:
received: 23 05 2023
accepted: 02 08 2023
medline: 18 8 2023
pubmed: 17 8 2023
entrez: 17 8 2023
Statut: epublish

Résumé

The recent advancements in messenger ribonucleic acid (mRNA) vaccine development have vastly enhanced their use as alternatives to conventional vaccines in the prevention of various infectious diseases and treatment of several types of cancers. This is mainly due to their remarkable ability to stimulate specific immune responses with minimal clinical side effects. This review gives a detailed overview of mRNA vaccines currently in use or at various stages of development, the recent advancements in mRNA vaccine development, and the challenges encountered in their development. Future perspectives on this technology are also discussed.

Identifiants

pubmed: 37589309
doi: 10.1088/1748-605X/aceceb
doi:

Substances chimiques

RNA, Messenger 0

Types de publication

Journal Article Review Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2023 IOP Publishing Ltd.

Auteurs

Londiwe Simphiwe Mbatha (LS)

Department of Biotechnology and Food Science, Durban University of Technology, PO Box 1334, Durban 4000, South Africa.

Jude Akinyelu (J)

Department of Biochemistry, Federal University Oye-Ekiti, Ekiti state, Nigeria.

Fiona Maiyo (F)

Department of Medical Sciences, Kabarak University, Nairobi, Kenya.

Tukayi Kudanga (T)

Department of Biotechnology and Food Science, Durban University of Technology, PO Box 1334, Durban 4000, South Africa.

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Classifications MeSH