Epigenetic signature of human immune aging in the GESTALT study.
DNA methylation
genetics
genomics
healthy aging
human
hypoxia
immune cells
immunology
inflammation
Journal
eLife
ISSN: 2050-084X
Titre abrégé: Elife
Pays: England
ID NLM: 101579614
Informations de publication
Date de publication:
17 08 2023
17 08 2023
Historique:
received:
12
01
2023
accepted:
16
08
2023
medline:
19
9
2023
pubmed:
17
8
2023
entrez:
17
8
2023
Statut:
epublish
Résumé
Age-associated DNA methylation in blood cells convey information on health status. However, the mechanisms that drive these changes in circulating cells and their relationships to gene regulation are unknown. We identified age-associated DNA methylation sites in six purified blood-borne immune cell types (naive B, naive CD4
Identifiants
pubmed: 37589453
doi: 10.7554/eLife.86136
pii: 86136
pmc: PMC10506794
doi:
pii:
Banques de données
GEO
['GSE184269']
Types de publication
Journal Article
Research Support, N.I.H., Intramural
Langues
eng
Sous-ensembles de citation
IM
Déclaration de conflit d'intérêts
RR, PK, JC, DS, CU, DH, MK, SA, AS, AB, JK, AM, TT, JM, LZ, CN, TW, CD, WW, YP, CC, SD, JS, NW, RS, LF No competing interests declared
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