Herpes simplex virus gene therapy for dystrophic epidermolysis bullosa (DEB).

Humans Epidermolysis Bullosa Dystrophica / genetics Genetic Therapy Herpesvirus 1, Human / genetics

Journal

Cell
ISSN: 1097-4172
Titre abrégé: Cell
Pays: United States
ID NLM: 0413066

Informations de publication

Date de publication:
17 08 2023
Historique:
medline: 21 8 2023
pubmed: 19 8 2023
entrez: 18 8 2023
Statut: ppublish

Résumé

The FDA has recently approved Krystal biotech's beremagene geperpavec (B-VEC, Vyjuvek) to treat the wounds of dystrophic epidermolysis bullosa (DEB) patients. This represents a giant step, not only toward the treatment of this devastating disease, but also for the whole field of non-replicative (nr) recombinant HSV-1 vectors for gene therapy. To view this Bench to Bedside, open or download the PDF.

Identifiants

DOI: 10.1016/j.cell.2023.07.031 PMID: 37595560
pubmed: 37595560
pii: S0092-8674(23)00809-7
doi: 10.1016/j.cell.2023.07.031
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

3523-3523.e1

Informations de copyright

Copyright © 2023 Elsevier Inc. All rights reserved.

Auteurs

Alberto L Epstein (AL)

EG427 Paris, France. Electronic address: alberto@eg427.com.

Cornelia Haag-Molkenteller (C)

EG427 Paris, France. Electronic address: cornelia@eg427.com.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Herpes simplex virus gene therapy for...
questionsmedicales.fr › Maladies de la peau et du tissu conjonctif › Maladies de la peau › Dermatoses vésiculobulleuses › Épidermolyse bulleuse › Épidermolyse bulleuse dystrophique › Herpes simplex virus gene therapy for...
questionsmedicales.fr › Techniques d'investigation › Techniques génétiques › Génie génétique › Thérapie génétique › Herpes simplex virus gene therapy for...
questionsmedicales.fr › Virus › Virus à ADN › Herpesviridae › Alphaherpesvirinae › Simplexvirus › Herpèsvirus humain de type 1 › Herpes simplex virus gene therapy for...