Osteopontin levels correlate with severity of diabetic cardiomyopathy in early stage of diabetes.

Humans Diabetic Cardiomyopathies Osteopontin Ventricular Dysfunction, Left / etiology Heart Failure / complications Diastole Diabetes Mellitus
Diabetic cardiomyopathy Echocardiography Osteopontin Type 2 diabetes mellitus

Journal

Diabetes research and clinical practice
ISSN: 1872-8227
Titre abrégé: Diabetes Res Clin Pract
Pays: Ireland
ID NLM: 8508335

Informations de publication

Date de publication:
Sep 2023
Historique:
received: 16 06 2023
revised: 07 08 2023
accepted: 17 08 2023
medline: 10 10 2023
pubmed: 21 8 2023
entrez: 20 8 2023
Statut: ppublish

Résumé

Diabetic cardiomyopathy (DbCM) is characterized by restrictive pattern and consistent risk of overt heart failure. We here focused osteopontin (OPN), which was tested independently associated with left ventricular diastolic dysfunction (LVDD). Overall, OPN increased with DbCM severity according with the presence of left atrial dilatation, LV hypertrophy and LVDD.

Identifiants

DOI: 10.1016/j.diabres.2023.110885 PMID: 37598938
pubmed: 37598938
pii: S0168-8227(23)00648-4
doi: 10.1016/j.diabres.2023.110885
pii:
doi:

Substances chimiques

Osteopontin 106441-73-0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

110885

Informations de copyright

Copyright © 2023. Published by Elsevier B.V.

Déclaration de conflit d'intérêts

Declaration of Competing Interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: [LL and GGC are coinventors on the International Patent WO/2020/226993 filed in April 2020. The patent relates to the use of antibodies which specifically bind IL-1α to reduce various sequelae of ischemia-reperfusion injury to the central nervous system. GGC is a consultant to Sovida solutions limited.].

Auteurs

Alessandro Scuricini (A)

First Clinic of Internal Medicine, Department of Internal Medicine, University of Genoa, 6 viale Benedetto XV, 16132 Genoa, Italy.

Francesco Andreozzi (F)

Department of Medical and Surgical Sciences, University "Magna Græcia" of Catanzaro, Catanzaro, Italy.

Cosimo Sgura (C)

First Clinic of Internal Medicine, Department of Internal Medicine, University of Genoa, 6 viale Benedetto XV, 16132 Genoa, Italy.

Stefano Ministrini (S)

Center for Molecular Cardiology, University of Zürich, 12 Wagistrasse, 8952 Schlieren, Switzerland.

Maria Bertolotto (M)

First Clinic of Internal Medicine, Department of Internal Medicine, University of Genoa, 6 viale Benedetto XV, 16132 Genoa, Italy.

Davide Ramoni (D)

First Clinic of Internal Medicine, Department of Internal Medicine, University of Genoa, 6 viale Benedetto XV, 16132 Genoa, Italy.

Luca Liberale (L)

First Clinic of Internal Medicine, Department of Internal Medicine, University of Genoa, 6 viale Benedetto XV, 16132 Genoa, Italy; IRCCS Ospedale Policlinico San Martino, Genoa - Italian Cardiovascular Network, 10 Largo Rosanna Benzi Genoa, Italy.

Giovanni G Camici (GG)

Center for Molecular Cardiology, University of Zürich, 12 Wagistrasse, 8952 Schlieren, Switzerland.

Gaia C Mannino (GC)

Department of Medical and Surgical Sciences, University "Magna Græcia" of Catanzaro, Catanzaro, Italy.

Elena Succurro (E)

Department of Medical and Surgical Sciences, University "Magna Græcia" of Catanzaro, Catanzaro, Italy.

Giuseppe Armentaro (G)

Department of Medical and Surgical Sciences, University "Magna Græcia" of Catanzaro, Catanzaro, Italy.

Teresa V Fiorentino (TV)

Department of Medical and Surgical Sciences, University "Magna Græcia" of Catanzaro, Catanzaro, Italy.

Velia Cassano (V)

Department of Medical and Surgical Sciences, University "Magna Græcia" of Catanzaro, Catanzaro, Italy.

Sofia Miceli (S)

Department of Medical and Surgical Sciences, University "Magna Græcia" of Catanzaro, Catanzaro, Italy.

Maria Perticone (M)

Department of Medical and Surgical Sciences, University "Magna Græcia" of Catanzaro, Catanzaro, Italy.

Mariangela Rubino (M)

Department of Medical and Surgical Sciences, University "Magna Græcia" of Catanzaro, Catanzaro, Italy.

Giorgio Sesti (G)

Department of Clinical and Molecular Medicine, University of Rome-Sapienza, Rome, Italy.

Fabrizio Montecucco (F)

First Clinic of Internal Medicine, Department of Internal Medicine, University of Genoa, 6 viale Benedetto XV, 16132 Genoa, Italy; IRCCS Ospedale Policlinico San Martino, Genoa - Italian Cardiovascular Network, 10 Largo Rosanna Benzi Genoa, Italy.

Angela Sciacqua (A)

Department of Medical and Surgical Sciences, University "Magna Græcia" of Catanzaro, Catanzaro, Italy.

Federico Carbone (F)

First Clinic of Internal Medicine, Department of Internal Medicine, University of Genoa, 6 viale Benedetto XV, 16132 Genoa, Italy; IRCCS Ospedale Policlinico San Martino, Genoa - Italian Cardiovascular Network, 10 Largo Rosanna Benzi Genoa, Italy. Electronic address: federico.carbone@unige.it.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Osteopontin levels correlate with severity of...
questionsmedicales.fr › Maladies endocriniennes › Diabète › Complications du diabète › Cardiomyopathies diabétiques › Osteopontin levels correlate with severity of...
questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Cytokines › Ostéopontine › Osteopontin levels correlate with severity of...
questionsmedicales.fr › Maladies cardiovasculaires › Cardiopathies › Dysfonction ventriculaire › Dysfonction ventriculaire gauche › Osteopontin levels correlate with severity of...
questionsmedicales.fr › Maladies cardiovasculaires › Cardiopathies › Défaillance cardiaque › Osteopontin levels correlate with severity of...
questionsmedicales.fr › Phénomènes physiologiques de l'appareil locomoteur et du système nerveux › Phénomènes physiologiques du système locomoteur › Contraction musculaire › Contraction myocardique › Diastole › Osteopontin levels correlate with severity of...
questionsmedicales.fr › Maladies endocriniennes › Diabète › Osteopontin levels correlate with severity of...