Journal

Frontiers in endocrinology
ISSN: 1664-2392
Titre abrégé: Front Endocrinol (Lausanne)
Pays: Switzerland
ID NLM: 101555782

Informations de publication

Date de publication:
2023
Historique:
received: 10 04 2023
accepted: 23 06 2023
medline: 22 8 2023
pubmed: 21 8 2023
entrez: 21 8 2023
Statut: epublish

Résumé

Idiopathic hypogonadotropic hypogonadism (IHH) is characterized by the absence of pubertal development and subsequent impaired fertility often due to gonadotropin-releasing hormone (GnRH) deficits. Exome sequencing of two independent cohorts of IHH patients identified 12 rare missense variants in

Identifiants

pubmed: 37600690
doi: 10.3389/fendo.2023.1203542
pmc: PMC10436210
doi:

Substances chimiques

Gonadotropin-Releasing Hormone 33515-09-2
POU Domain Factors 0
POU6F2 protein, human 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1203542

Informations de copyright

Copyright © 2023 Cho, Gurbuz, Stamou, Kotan, Farmer, Can, Tompkins, Mammadova, Altincik, Gokce, Catli, Bugrul, Bartlett, Turan, Balasubramanian, Yuksel, Seminara, Wray and Topaloglu.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Hyun-Ju Cho (HJ)

Cellular and Developmental Neurobiology Section, National Institute of Neurologic Disorders and Stroke, National Institutes of Health, Bethesda, MD, United States.

Fatih Gurbuz (F)

Division of Pediatric Endocrinology, Faculty of Medicine, Cukurova University, Adana, Türkiye.

Maria Stamou (M)

Harvard Reproductive Sciences Center, The Reproductive Endocrine Unit and The Endocrine Unit of the Department of Medicine, Massachusetts General Hospital, Boston, MA, United States.

Leman Damla Kotan (LD)

Division of Pediatric Endocrinology, Faculty of Medicine, Cukurova University, Adana, Türkiye.

Stephen Matthew Farmer (SM)

Cellular and Developmental Neurobiology Section, National Institute of Neurologic Disorders and Stroke, National Institutes of Health, Bethesda, MD, United States.

Sule Can (S)

Division of Pediatric Endocrinology, İzmir Tepecik Training and Research Hospital, Health Sciences University, İzmir, Türkiye.

Miranda Faith Tompkins (MF)

Cellular and Developmental Neurobiology Section, National Institute of Neurologic Disorders and Stroke, National Institutes of Health, Bethesda, MD, United States.

Jamala Mammadova (J)

Division of Pediatric Endocrinology, Faculty of Medicine, Ondokuz Mayis University, Samsun, Türkiye.

S Ayca Altincik (SA)

Division of Pediatric Endocrinology, Faculty of Medicine, Pamukkale University, Denizli, Türkiye.

Cumali Gokce (C)

Division of Endocrinology, Faculty of Medicine, Mustafa Kemal University, Hatay, Türkiye.

Gonul Catli (G)

Division of Pediatric Endocrinology, İzmir Tepecik Training and Research Hospital, Health Sciences University, İzmir, Türkiye.

Fuat Bugrul (F)

Division of Pediatric Endocrinology, Faculty of Medicine, Selcuk University, Konya, Türkiye.

Keenan Bartlett (K)

Cellular and Developmental Neurobiology Section, National Institute of Neurologic Disorders and Stroke, National Institutes of Health, Bethesda, MD, United States.

Ihsan Turan (I)

Division of Pediatric Endocrinology, Faculty of Medicine, Cukurova University, Adana, Türkiye.

Ravikumar Balasubramanian (R)

Harvard Reproductive Sciences Center, The Reproductive Endocrine Unit and The Endocrine Unit of the Department of Medicine, Massachusetts General Hospital, Boston, MA, United States.

Bilgin Yuksel (B)

Division of Pediatric Endocrinology, Faculty of Medicine, Cukurova University, Adana, Türkiye.

Stephanie B Seminara (SB)

Harvard Reproductive Sciences Center, The Reproductive Endocrine Unit and The Endocrine Unit of the Department of Medicine, Massachusetts General Hospital, Boston, MA, United States.

Susan Wray (S)

Cellular and Developmental Neurobiology Section, National Institute of Neurologic Disorders and Stroke, National Institutes of Health, Bethesda, MD, United States.

A Kemal Topaloglu (AK)

Department of Pediatrics, Division of Pediatric Endocrinology, University of Mississippi Medical Center, Jackson, MS, United States.
Division of Pediatric Endocrinology, Massachusetts General Hospital for Children and Harvard Medical School, Boston, MS, United States.

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Classifications MeSH