Biological Macromolecule-Based Scaffolds for Urethra Reconstruction.

biological macromolecules tissue engineering urethra defects urethra reconstruction

Journal

Biomolecules
ISSN: 2218-273X
Titre abrégé: Biomolecules
Pays: Switzerland
ID NLM: 101596414

Informations de publication

Date de publication:
26 07 2023
Historique:
received: 12 06 2023
revised: 17 07 2023
accepted: 17 07 2023
medline: 28 8 2023
pubmed: 26 8 2023
entrez: 26 8 2023
Statut: epublish

Résumé

Urethral reconstruction strategies are limited with many associated drawbacks. In this context, the main challenge is the unavailability of a suitable tissue that can endure urine exposure. However, most of the used tissues in clinical practices are non-specialized grafts that finally fail to prevent urine leakage. Tissue engineering has offered novel solutions to address this dilemma. In this technology, scaffolding biomaterials characteristics are of prime importance. Biological macromolecules are naturally derived polymers that have been extensively studied for various tissue engineering applications. This review discusses the recent advances, applications, and challenges of biological macromolecule-based scaffolds in urethral reconstruction.

Identifiants

pubmed: 37627232
pii: biom13081167
doi: 10.3390/biom13081167
pmc: PMC10452429
pii:
doi:

Substances chimiques

Biocompatible Materials 0
Polymers 0

Types de publication

Journal Article Review Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

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Auteurs

Saeed Farzamfar (S)

Centre de Recherche en Organogénèse Expérimentale/LOEX, Regenerative Medicine Division, CHU de Québec-Université Laval Research Center, Quebec, QC G1V 4G2, Canada.

Megan Richer (M)

Centre de Recherche en Organogénèse Expérimentale/LOEX, Regenerative Medicine Division, CHU de Québec-Université Laval Research Center, Quebec, QC G1V 4G2, Canada.

Mahya Rahmani (M)

Department of Tissue Engineering and Applied Cell Sciences, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, Tehran 1983963113, Iran.

Mohammad Naji (M)

Urology and Nephrology Research Center, Shahid Beheshti University of Medical Sciences, Tehran 1983963113, Iran.

Mehdi Aleahmad (M)

Department of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran 1417613151, Iran.

Stéphane Chabaud (S)

Centre de Recherche en Organogénèse Expérimentale/LOEX, Regenerative Medicine Division, CHU de Québec-Université Laval Research Center, Quebec, QC G1V 4G2, Canada.

Stéphane Bolduc (S)

Centre de Recherche en Organogénèse Expérimentale/LOEX, Regenerative Medicine Division, CHU de Québec-Université Laval Research Center, Quebec, QC G1V 4G2, Canada.
Department of Surgery, Faculty of Medicine, Laval University, Quebec, QC G1V 0A6, Canada.

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Classifications MeSH