A Novel Transgenic Mouse Model Implicates


Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
09 Aug 2023
Historique:
received: 28 06 2023
revised: 28 07 2023
accepted: 04 08 2023
medline: 28 8 2023
pubmed: 26 8 2023
entrez: 26 8 2023
Statut: epublish

Résumé

Hepatocellular carcinoma (HCC) is one of the leading causes of cancer deaths globally. Incidence rates are steadily increasing, creating an unmet need for new therapeutic options. Recently, the inhibition of sirtuin-2 (

Identifiants

pubmed: 37628798
pii: ijms241612618
doi: 10.3390/ijms241612618
pmc: PMC10454864
pii:
doi:

Substances chimiques

Sirtuin 2 EC 3.5.1.-
Carcinogens 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : NIH HHS
ID : DK090242
Pays : United States

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Auteurs

Alexandra V Schmidt (AV)

Division of Genetic and Genomic Medicine, Department of Pediatrics, University of Pittsburgh School of Medicine, University of Pittsburgh, Pittsburgh, PA 15260, USA.

Satdarshan P Monga (SP)

Pittsburgh Liver Research Center, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA.
Division of Experimental Pathology, Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.
Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.

Edward V Prochownik (EV)

Pittsburgh Liver Research Center, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA.
Division of Hematology and Oncology, Department of Pediatrics, University of Pittsburgh School of Medicine, University of Pittsburgh, Pittsburgh, PA 15260, USA.

Eric S Goetzman (ES)

Division of Genetic and Genomic Medicine, Department of Pediatrics, University of Pittsburgh School of Medicine, University of Pittsburgh, Pittsburgh, PA 15260, USA.
Pittsburgh Liver Research Center, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA.

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Classifications MeSH