Three-Year Follow-Up after Intrauterine mTOR Inhibitor Administration for Fetus with TSC-Associated Rhabdomyoma.


Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
17 Aug 2023
Historique:
received: 30 06 2023
revised: 14 08 2023
accepted: 15 08 2023
medline: 28 8 2023
pubmed: 26 8 2023
entrez: 26 8 2023
Statut: epublish

Résumé

Tuberous sclerosis complex (TSC) is a multisystem disorder characterized by seizures, neuropsychiatric disorders, and tumors of the heart, brain, skin, lungs, and kidneys. We present a three-year follow-up of a patient with TSC-associated rhabdomyoma detected in utero. Genetic examination of the fetus and the parents revealed a de novo variant in the

Identifiants

pubmed: 37629066
pii: ijms241612886
doi: 10.3390/ijms241612886
pmc: PMC10454323
pii:
doi:

Substances chimiques

Everolimus 9HW64Q8G6G
MTOR Inhibitors 0
TOR Serine-Threonine Kinases EC 2.7.11.1

Types de publication

Case Reports

Langues

eng

Sous-ensembles de citation

IM

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Auteurs

Anita Maász (A)

Department of Medical Genetics, Medical School and Clinical Centre, University of Pécs, H-7624 Pécs, Hungary.

Tímea Bodó (T)

Bethesda Children's Hospital, H-1146 Budapest, Hungary.

Ágnes Till (Á)

Department of Medical Genetics, Medical School and Clinical Centre, University of Pécs, H-7624 Pécs, Hungary.

Gábor Molnár (G)

Department of Obstetrics and Gynaecology, Medical School and Clinical Centre, University of Pécs, H-7624 Pécs, Hungary.

György Masszi (G)

Department of Paediatrics, Medical School and Clinical Centre, University of Pécs, H-7624 Pécs, Hungary.

Gusztáv Labossa (G)

Department of Obstetrics and Gynaecology, Medical School and Clinical Centre, University of Pécs, H-7624 Pécs, Hungary.

Zsuzsanna Herbert (Z)

Department of Medical Imaging, Medical School and Clinical Centre, University of Pécs, H-7624 Pécs, Hungary.

Judit Bene (J)

Department of Medical Genetics, Medical School and Clinical Centre, University of Pécs, H-7624 Pécs, Hungary.

Kinga Hadzsiev (K)

Department of Medical Genetics, Medical School and Clinical Centre, University of Pécs, H-7624 Pécs, Hungary.

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Classifications MeSH