Determination of o-phthalaldehyde for dose verification of the clinical disinfectant by fluorescent sequential injection analysis.
Disinfectant
Fluorimetry
Sequential injection analysis (SIA)
o-Phthalaldehyde (OPA)
Journal
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry
ISSN: 1348-2246
Titre abrégé: Anal Sci
Pays: Switzerland
ID NLM: 8511078
Informations de publication
Date de publication:
Dec 2023
Dec 2023
Historique:
received:
23
05
2023
accepted:
17
08
2023
medline:
27
11
2023
pubmed:
27
8
2023
entrez:
26
8
2023
Statut:
ppublish
Résumé
A new automated, generic analytical approach for determining the clinical disinfectant o-phthalaldehyde (OPA) is reported in this study. The proposed sequential injection analysis (SIA) is based on the online reaction of the OPA with glycine/N-acetylcysteine (NAC) in a neutral medium (pH = 7.0) to form a highly fluorescent isoindole derivative. All critical flow and reaction variables were investigated, while validation was carried out in the linearity detection range (0.0075-0.02%). As a result, excellent linearity (R
Identifiants
pubmed: 37632646
doi: 10.1007/s44211-023-00415-4
pii: 10.1007/s44211-023-00415-4
doi:
Substances chimiques
o-Phthalaldehyde
643-79-8
Disinfectants
0
Glutaral
T3C89M417N
Coloring Agents
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
2007-2017Subventions
Organisme : Ministry of Science and Technology of Taiwan
ID : MOST-105-2313-B-002-022
Organisme : Ministry of Science and Technology of Taiwan
ID : MOST-107-2313-B-002-015
Informations de copyright
© 2023. The Author(s), under exclusive licence to The Japan Society for Analytical Chemistry.
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