Absorbed dose evaluation of a blood irradiator with alanine, TLD-100 and ionization chamber.

Alanine Blood irradiation X-Ray irradiator Dose mapping Ion chamber Raycell MK2 TLD dosimetry

Journal

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine
ISSN: 1872-9800
Titre abrégé: Appl Radiat Isot
Pays: England
ID NLM: 9306253

Informations de publication

Date de publication:
Oct 2023
Historique:
received: 09 03 2023
revised: 20 07 2023
accepted: 11 08 2023
medline: 5 9 2023
pubmed: 27 8 2023
entrez: 26 8 2023
Statut: ppublish

Résumé

Irradiation of blood bags using X-ray irradiators and dosimetry services are required to ensure uniform dose levels in the range 25-50 Gy to prevent Transfusion Associated Graft versus Host Disease (TA-GvHD). An absorbed dose characterization of a Raycell MK2 X-Irradiator was performed using three different dosimetric systems. Results showed a dosimetric accuracy of the ionization chamber together with the Alanine dosimeter. TLDs measurements exhibited a small overestimation by 4% of the absorbed dose. The Dose Uniformity Ratio (DUR), between maximum and minimum dose levels in the canister, was in good agreement with the manufacturer specifications (≤1.5).

Identifiants

pubmed: 37633189
pii: S0969-8043(23)00334-2
doi: 10.1016/j.apradiso.2023.110981
pii:
doi:

Substances chimiques

Alanine OF5P57N2ZX

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

110981

Informations de copyright

Copyright © 2023 The Authors. Published by Elsevier Ltd.. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Auteurs

S Grasso (S)

Post Graduate School in Medical Physics, University of Naples Federico II, 80131, Naples, Italy.

A Varallo (A)

Post Graduate School in Medical Physics, University of Naples Federico II, 80131, Naples, Italy; National Institute of Nuclear Physics, 80126, Naples, Italy.

R Ricciardi (R)

Post Graduate School in Medical Physics, University of Naples Federico II, 80131, Naples, Italy; National Institute of Nuclear Physics, 80126, Naples, Italy.

M E Italiano (ME)

Post Graduate School in Medical Physics, University of Naples Federico II, 80131, Naples, Italy.

C Oliviero (C)

Unit of Medical Physics and Radioprotection, A.O.U Policlinico Federico II, 80131, Naples, Italy.

V D'Avino (V)

Department of Physics "E. Pancini", University of Naples Federico II, 80126, Naples, Italy.

C Feoli (C)

Department of Advanced Biomedical Sciences, University of Naples Federico II, 80131, Naples, Italy.

F Ambrosino (F)

Department of Physics "E. Pancini", University of Naples Federico II, 80126, Naples, Italy.

M Pugliese (M)

Department of Physics "E. Pancini", University of Naples Federico II, 80126, Naples, Italy. Electronic address: mpuglies@na.infn.it.

S Clemente (S)

Unit of Medical Physics and Radioprotection, A.O.U Policlinico Federico II, 80131, Naples, Italy.

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Classifications MeSH