Forensically relevant challenging behaviors and the genetics domain.

Challenging behavior Contextual neuropsychology Genetic syndromes Intellectual disability Neurodevelopmental disorder Pharmacotherapy

Journal

Handbook of clinical neurology
ISSN: 0072-9752
Titre abrégé: Handb Clin Neurol
Pays: Netherlands
ID NLM: 0166161

Informations de publication

Date de publication:
2023
Historique:
medline: 28 8 2023
pubmed: 27 8 2023
entrez: 26 8 2023
Statut: ppublish

Résumé

Impulsive and aggressive behaviors along with intellectual disabilities often manifest in the context of genetic disorders and are a persisting challenge to professionals in the forensic psychiatric and psychological setting. The following chapter comprises an overview of relevant factors in the gene-context-behavior interaction such as monoamine oxidase A activity and specific epileptic phenomena. It presents several examples of monogenetic disorders with behaviors from the aggression spectrum and summarizes emerging strategies for treatment and clinical management thereof. The final part focuses on challenges and future developments in this field with relevance for the judicial and forensic systems. It is concluded that the relationship between a genetic syndrome and forensically relevant and/or violent behaviors should typically be addressed within a multidisciplinary framework that also includes the application of modern genetic techniques.

Identifiants

pubmed: 37633719
pii: B978-0-12-821375-9.00007-4
doi: 10.1016/B978-0-12-821375-9.00007-4
pii:
doi:

Types de publication

Review Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

65-73

Informations de copyright

Copyright © 2023 Elsevier B.V. All rights reserved.

Auteurs

Jos I M Egger (JIM)

Donders Institute for Brain, Cognition and Behaviour and Radboudumc Center of Expertise on Rare Congenital Developmental Disorders, Radboud University, Nijmegen, The Netherlands; Centre of Excellence for Neuropsychiatry, Vincent van Gogh Institute for Psychiatry, Venray, The Netherlands. Electronic address: jos.egger@donders.ru.nl.

Willem M A Verhoeven (WMA)

Centre of Excellence for Neuropsychiatry, Vincent van Gogh Institute for Psychiatry, Venray, The Netherlands; Department of Psychiatry, Erasmus University Medical Center, Rotterdam, The Netherlands.

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Classifications MeSH