Clinical findings and prognostic factors for mortality in hospitalized dogs with leishmaniosis: aretrospective study.


Journal

Comparative immunology, microbiology and infectious diseases
ISSN: 1878-1667
Titre abrégé: Comp Immunol Microbiol Infect Dis
Pays: England
ID NLM: 7808924

Informations de publication

Date de publication:
Oct 2023
Historique:
received: 20 06 2023
revised: 15 08 2023
accepted: 22 08 2023
medline: 23 10 2023
pubmed: 28 8 2023
entrez: 27 8 2023
Statut: ppublish

Résumé

This retrospective study evaluated factors responsible for mortality of dogs hospitalized for Canine Leishmaniosis. Medical records of 31 dogs with leishmaniosis from a Portuguese Veterinary Teaching Hospital were examined between August 2018 and January 2022. Females (n = 18) and pure breed dogs (n = 27) were overrepresented, with higher frequency of Labrador Retriever (n = 4). Median age was 7 years (interquartile range=7). Most had historical findings of lethargy (n = 26) and the commonest clinicopathological abnormality was hypoalbuminemia (n = 26). Eleven dogs were classified as LeishVet stage II, 10 stage III and 10 stage IV. Fourteen dogs (45.2%) died or were euthanized, with azotemia, leukocytosis, stage IV, absence of diagnosis before hospitalization and lack of leishmaniosis specific treatment during hospitalization contributing to mortality. Absence of hypoalbuminemia and stages II/III increased survival. Mean hospitalization length prior to discharge was 5.41days ( ± 1.84) and diarrhea prolonged hospital stay.

Identifiants

pubmed: 37634471
pii: S0147-9571(23)00099-1
doi: 10.1016/j.cimid.2023.102041
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

102041

Informations de copyright

Copyright © 2023 The Authors. Published by Elsevier Ltd.. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. The authors declare that they have no competing interests. Over the last two years, ROL and MJD were involved in two research trials on Canine Leishmaniosis (Nestle Purina and Bioiberica), both unrelated with this study.

Auteurs

Carlota Carvalho Molina (CC)

Hospital Escolar Veterinário, Faculty of Veterinary Medicine, University of Lisbon, Lisbon, Portugal. Electronic address: cmolina@campus.ul.pt.

Maria Joana Dias (MJ)

Hospital Escolar Veterinário, Faculty of Veterinary Medicine, University of Lisbon, Lisbon, Portugal; Centre for Interdisciplinary Research in Animal Health (CIISA) , Faculty of Veterinary Medicine, University of Lisbon, Lisbon, Portugal; Associate Laboratory for Animal and Veterinary Sciences (AL4AnimalS), Lisbon, Portugal. Electronic address: joanadias@fmv.ulisboa.pt.

Tiago Dias Domingues (TD)

CEAUL, Faculdade de Ciências, University of Lisbon, Lisbon, Portugal. Electronic address: tmdomingues@fc.ul.pt.

Ryane E Englar (RE)

College of Veterinary Medicine, University of Arizona, Oro Valley, USA. Electronic address: renglar@arizona.edu.

Rodolfo Oliveira Leal (RO)

Hospital Escolar Veterinário, Faculty of Veterinary Medicine, University of Lisbon, Lisbon, Portugal; Centre for Interdisciplinary Research in Animal Health (CIISA) , Faculty of Veterinary Medicine, University of Lisbon, Lisbon, Portugal; Associate Laboratory for Animal and Veterinary Sciences (AL4AnimalS), Lisbon, Portugal. Electronic address: rleal@fmv.ulisboa.pt.

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Classifications MeSH