[Evolution of the obstetrical Shock Index in postpartum haemorrhage according to the use of sulprostone].

Évolution du Shock Index obstétrical lors d’une hémorragie du post-partum selon le recours à la sulprostone.
Haemodynamic parameters Hémorragie du post-partum Paramètres hémodynamiques Postpartulm haemorrhage Shock Index Sulprostone

Journal

Gynecologie, obstetrique, fertilite & senologie
ISSN: 2468-7189
Titre abrégé: Gynecol Obstet Fertil Senol
Pays: France
ID NLM: 101693805

Informations de publication

Date de publication:
10 2023
Historique:
received: 13 02 2023
revised: 30 06 2023
accepted: 08 08 2023
medline: 2 10 2023
pubmed: 28 8 2023
entrez: 27 8 2023
Statut: ppublish

Résumé

The Shock Index (SI) is used in emergency medicine to assess the severity of active bleeding and in the postpartum context for postpartum haemorrhage (PPH). We investigated the diagnostic value of haemodynamic parameters (SI, heart rate (HR), systolic blood pressure (SBP), diastolic blood pressure (DBP) and mean arterial pressure (MAP)) in predicting subsequent use of uterotonic sulprostone treatment. This was a retrospective study including parturients with PPH ≥ 500mL between January 2017 and December 2018. Hemodynamic parameters at the diagnosis of PPH were compared according to whether the patient required subsequent sulprostone treatment (sulprostone(+) group) or not (sulprostone(-) group). We included in the analysis 147 patients. The SI was significantly higher in the sulprostone(+) group (0.92±0.28 vs. 0.83±0.22; p=0.04). The SBP (107.2±17.5 vs. 113.8±17.7mmHg; p=0.03), DBP (56.8±12,2 vs. 61.5±13,2mmHg; p=0.04), MAP (73.6±12.6 vs. 78.5±13.4mmHg; p=0.03) were significantly lower in the same group. No difference between AUC of these parameters to predict the use of sulprostone was found (AUC between 0.59 and 0.61). No significant difference was found for the HR between the two groups. The diagnostic value of SI appeared to be low and similar to other haemodynamic parameters in predicting the use of sulprostone.

Identifiants

pubmed: 37634804
pii: S2468-7189(23)00162-9
doi: 10.1016/j.gofs.2023.08.001
pii:
doi:

Substances chimiques

sulprostone 501Q5EQ1GM
Dinoprostone K7Q1JQR04M

Types de publication

English Abstract Journal Article

Langues

fre

Sous-ensembles de citation

IM

Pagination

448-454

Informations de copyright

Copyright © 2023 Elsevier Masson SAS. All rights reserved.

Auteurs

Romain Cahierc (R)

Obstetrics and Gynaecology Department, CHU Clermont-Ferrand, 63000 Clermont-Ferrand, France; Université Clermont Auvergne, CHU, CNRS, SIGMA Clermont, Institut Pascal, 63000 Clermont-Ferrand, France. Electronic address: rcahierc@chu-clermontferrand.fr.

Anne Debost-Legrand (A)

Université Clermont Auvergne, CHU, CNRS, SIGMA Clermont, Institut Pascal, 63000 Clermont-Ferrand, France.

Sophie Lane (S)

Medical School, université Clermont-Auvergne, 63000 Clermont-Ferrand, France.

Marion Rouzaire (M)

Obstetrics and Gynaecology Department, CHU Clermont-Ferrand, 63000 Clermont-Ferrand, France.

Martine Bonnin (M)

Department of Anesthesia, CHU Clermont-Ferrand, 63000 Clermont-Ferrand, France.

Amélie Delabaere (A)

Obstetrics and Gynaecology Department, CHU Clermont-Ferrand, 63000 Clermont-Ferrand, France; Université Clermont Auvergne, CHU, CNRS, SIGMA Clermont, Institut Pascal, 63000 Clermont-Ferrand, France.

Denis Gallot (D)

Obstetrics and Gynaecology Department, CHU Clermont-Ferrand, 63000 Clermont-Ferrand, France; Team "Translational approach to epithelial injury and repair", université Clermont-Auvergne, CNRS, Inserm, GReD, 63000 Clermont-Ferrand, France.

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