Characterization of human umbilical cord blood-derived mast cells using high-throughput expression profiling and next-generation knowledge discovery platforms.

Humans Mast Cells Fetal Blood Knowledge Discovery Antigens, CD34 / genetics Cell Differentiation / genetics
CD117 Cord blood Immunoglobulin E Innate immunity Mast cells Next generation knowledge discovery

Journal

Experimental and molecular pathology
ISSN: 1096-0945
Titre abrégé: Exp Mol Pathol
Pays: Netherlands
ID NLM: 0370711

Informations de publication

Date de publication:
08 2023
Historique:
received: 10 07 2023
revised: 09 08 2023
accepted: 14 08 2023
medline: 19 9 2023
pubmed: 28 8 2023
entrez: 27 8 2023
Statut: ppublish

Résumé

Mast cells (MCs) are tissue-resident innate immune cells that express the high-affinity receptor for immunoglobulin E and are responsible for host defense and an array of diseases related to immune system. We aimed in this study to characterize the pathways and gene signatures of human cord blood-derived MCs (hCBMCs) in comparison to cells originating from CD34

Identifiants

DOI: 10.1016/j.yexmp.2023.104867 PMID: 37634863
pubmed: 37634863
pii: S0014-4800(23)00018-7
doi: 10.1016/j.yexmp.2023.104867
pii:
doi:

Substances chimiques

Antigens, CD34 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

104867

Informations de copyright

Copyright © 2023. Published by Elsevier Inc.

Déclaration de conflit d'intérêts

Declaration of competing interest The authors declare that there are no conflicts of interest.

Auteurs

Sherin Bakhashab (S)

Biochemistry Department, King Abdulaziz University, Jeddah, Saudi Arabia; Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia. Electronic address: sbakhashab@kau.edu.sa.

Ghalya H Banafea (GH)

Biochemistry Department, King Abdulaziz University, Jeddah, Saudi Arabia.

Farid Ahmed (F)

Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia; Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.

Haneen Alsehli (H)

Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia; Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia; Centre for Stem Cells & Regenerative Medicine, King's College London, UK.

Huda F AlShaibi (HF)

Biochemistry Department, King Abdulaziz University, Jeddah, Saudi Arabia.

Nadia Bagatian (N)

Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia.

Ohoud Subhi (O)

Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia.

Kalamegam Gauthaman (K)

Center for Transdisciplinary Research, Department of Pharmacology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India.

Mahmood Rasool (M)

Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia; Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.

Hans-Juergen Schulten (HJ)

Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia; Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.

Peter Natesan Pushparaj (PN)

Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia; Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia; Center for Transdisciplinary Research, Department of Pharmacology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India. Electronic address: peter.n.pushparaj@gmail.com.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Characterization of human umbilical cord...
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Mastocytes › Characterization of human umbilical cord...
questionsmedicales.fr › Structures de l'embryon › Foetus › Sang foetal › Characterization of human umbilical cord...
questionsmedicales.fr › Sciences de l'information › Sources d'information › Moyens de communication › Publications › Découverte de connaissances basée sur la littérature › Characterization of human umbilical cord...
questionsmedicales.fr › Facteurs biologiques › Marqueurs biologiques › Antigènes de différenciation › Antigènes CD › Antigènes CD34 › Characterization of human umbilical cord...
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Différenciation cellulaire › Characterization of human umbilical cord...