Journal

bioRxiv : the preprint server for biology
Titre abrégé: bioRxiv
Pays: United States
ID NLM: 101680187

Informations de publication

Date de publication:
23 Aug 2023
Historique:
pubmed: 4 9 2023
medline: 4 9 2023
entrez: 4 9 2023
Statut: epublish

Résumé

In natural proteins, structured loops play central roles in molecular recognition, signal transduction and enzyme catalysis. However, because of the intrinsic flexibility and irregularity of loop regions, organizing multiple structured loops at protein functional sites has been very difficult to achieve by

Identifiants

DOI: 10.1101/2023.08.22.554384 PMID: 37662224 PMC: PMC10473674
pubmed: 37662224
doi: 10.1101/2023.08.22.554384
pmc: PMC10473674
pii:
doi:

Types de publication

Preprint

Langues

eng

Subventions

Organisme : NIGMS NIH HHS
ID : P30 GM133894
Pays : United States
Organisme : NIGMS NIH HHS
ID : P30 GM138396
Pays : United States
Organisme : NIH HHS
ID : S10 OD012289
Pays : United States

Auteurs

Hanlun Jiang (H)

Department of Biochemistry, University of Washington.
Institute for Protein Design, University of Washington.

Kevin M Jude (KM)

Howard Hughes Medical Institute, Stanford University School of Medicine.

Kejia Wu (K)

Department of Biochemistry, University of Washington.
Institute for Protein Design, University of Washington.
Biological Physics, Structure and Design Graduate Program, University of Washington.

Jorge Fallas (J)

Department of Biochemistry, University of Washington.
Institute for Protein Design, University of Washington.

George Ueda (G)

Department of Biochemistry, University of Washington.
Institute for Protein Design, University of Washington.

T J Brunette (TJ)

Department of Biochemistry, University of Washington.
Institute for Protein Design, University of Washington.

Derrick Hicks (D)

Department of Biochemistry, University of Washington.
Institute for Protein Design, University of Washington.

Harley Pyles (H)

Department of Biochemistry, University of Washington.
Institute for Protein Design, University of Washington.

Aerin Yang (A)

Department of Molecular and Cellular Physiology, Stanford University School of Medicine.

Lauren Carter (L)

Department of Biochemistry, University of Washington.
Institute for Protein Design, University of Washington.

Mila Lamb (M)

Department of Biochemistry, University of Washington.
Institute for Protein Design, University of Washington.

Xinting Li (X)

Department of Biochemistry, University of Washington.
Institute for Protein Design, University of Washington.

Paul M Levine (PM)

Department of Biochemistry, University of Washington.
Institute for Protein Design, University of Washington.

Lance Stewart (L)

Department of Biochemistry, University of Washington.
Institute for Protein Design, University of Washington.

K Christopher Garcia (KC)

Howard Hughes Medical Institute, Stanford University School of Medicine.
Department of Molecular and Cellular Physiology, Stanford University School of Medicine.
Department of Structural Biology, Stanford University School of Medicine.

David Baker (D)

Department of Biochemistry, University of Washington.
Institute for Protein Design, University of Washington.
Howard Hughes Medical Institute, Stanford University School of Medicine.
Howard Hughes Medical Institute, University of Washington.

Classifications MeSH