The effect of magnesium sulfate on gene expression and serum level of inflammatory cytokines in coronary artery disease patients.
Coronary artery disease
Inflammatory cytokines
Magnesium sulfate
Journal
Inflammopharmacology
ISSN: 1568-5608
Titre abrégé: Inflammopharmacology
Pays: Switzerland
ID NLM: 9112626
Informations de publication
Date de publication:
Oct 2023
Oct 2023
Historique:
received:
16
04
2023
accepted:
21
08
2023
medline:
26
9
2023
pubmed:
4
9
2023
entrez:
4
9
2023
Statut:
ppublish
Résumé
To evaluate the effect of oral magnesium sulfate (MgSO 60 CAD patients were selected based on angiography findings and were randomly divided into two groups that received 300 mg/day MgSO After 3 months of intervention, gene expression and serum levels of IL-18 and TNF-α in the MgSO The results of our study demonstrate that 3-month magnesium sulfate administration (300 mg/day) to CAD patients could significantly decrease serum concentration and gene expression levels of IL-18 and TNF-α. Our findings support the potential beneficial effect of magnesium supplementation on alleviating CAD complications through modulating inflammatory cytokines.
Identifiants
pubmed: 37665448
doi: 10.1007/s10787-023-01328-4
pii: 10.1007/s10787-023-01328-4
doi:
Substances chimiques
Cytokines
0
Interleukin-18
0
Tumor Necrosis Factor-alpha
0
Magnesium Sulfate
7487-88-9
Interleukin-6
0
Types de publication
Randomized Controlled Trial
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
2421-2430Informations de copyright
© 2023. The Author(s), under exclusive licence to Springer Nature Switzerland AG.
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