Evaluation of the correlation of dorsal root ganglia and spinal nerves with clinical symptoms in patients with postherpetic neuralgia using magnetic resonance neurography.
Clinical symptoms
Dorsal root ganglion
Magnetic resonance neurography
Morphology
Postherpetic neuralgia
Journal
PeerJ
ISSN: 2167-8359
Titre abrégé: PeerJ
Pays: United States
ID NLM: 101603425
Informations de publication
Date de publication:
2023
2023
Historique:
received:
28
04
2023
accepted:
08
08
2023
medline:
6
9
2023
pubmed:
5
9
2023
entrez:
5
9
2023
Statut:
epublish
Résumé
To assess changes of dorsal root ganglia (DRG) and spinal nerves in patients with postherpetic neuralgia (PHN), and investigate the correlation between DRG morphology and clinical symptoms in PHN patients using magnetic resonance neurography (MRN). In this case-control study, forty-nine lesioned DRG in 30 patients and 49 normal DRG in 30 well-matched (age, sex, height, weight) healthy controls were assessed. Clinical symptoms of patients (pain, allodynia, itching, and numbness) were assessed. MRN features (DRG volume (V The volume and relative M-value of lesioned DRG in patients were significantly higher than those on the same side of healthy controls ( DRG and spinal nerves on the lesioned side are swollen during PHN. Disease duration is an independent risk factor for morphological differences in the lesioned DRG of PHN patients. This study provides important guidance for individualized treatments of PHN.
Identifiants
pubmed: 37667753
doi: 10.7717/peerj.15998
pii: 15998
pmc: PMC10475274
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e15998Informations de copyright
© 2023 Cao et al.
Déclaration de conflit d'intérêts
The authors declare that they have no competing interests.
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