Dyslexia-related loci are significantly associated with language and literacy in Chinese-English bilingual Hong Kong Chinese twins.
Journal
Human genetics
ISSN: 1432-1203
Titre abrégé: Hum Genet
Pays: Germany
ID NLM: 7613873
Informations de publication
Date de publication:
Oct 2023
Oct 2023
Historique:
received:
02
05
2023
accepted:
10
08
2023
medline:
21
9
2023
pubmed:
5
9
2023
entrez:
5
9
2023
Statut:
ppublish
Résumé
A recent genome-wide association study on dyslexia in 51,800 affected European adults and 1,087,070 controls detected 42 genome-wide significant single nucleotide variants (SNPs). The association between rs2624839 in SEMA3F and reading fluency was replicated in a Chinese cohort. This study explores the genetic overlap between Chinese and English word reading, vocabulary knowledge and spelling, and aims at replicating the association in a unique cohort of bilingual (Chinese-English) Hong Kong Chinese twins. Our result showed an almost complete genetic overlap in vocabulary knowledge (r
Identifiants
pubmed: 37668838
doi: 10.1007/s00439-023-02594-6
pii: 10.1007/s00439-023-02594-6
doi:
Substances chimiques
SEMA3F protein, human
0
Membrane Proteins
0
Nerve Tissue Proteins
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1519-1529Subventions
Organisme : Research Grants Council (RGC) of Hong Kong
ID : C4054-17WF
Organisme : Research Grants Council (RGC) of Hong Kong
ID : T44-410/21-N
Informations de copyright
© 2023. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.
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