IS

Escherichia coli IS1 elements comparative genomics hybrid genome assembly insertion sequences nitrofurantoin heteroresistance population analysis profiling resistance mechanism structural variation whole-genome sequencing

Journal

Microbial genomics
ISSN: 2057-5858
Titre abrégé: Microb Genom
Pays: England
ID NLM: 101671820

Informations de publication

Date de publication:
09 2023
Historique:
medline: 7 9 2023
pubmed: 6 9 2023
entrez: 6 9 2023
Statut: ppublish

Résumé

Nitrofurantoin is a broad-spectrum first-line antimicrobial used for managing uncomplicated urinary tract infection (UTI). Loss-of-function mutations in chromosomal genes

Identifiants

pubmed: 37672334
doi: 10.1099/mgen.0.001102
pmc: PMC10569738
doi:

Substances chimiques

Nitrofurantoin 927AH8112L
Nitroreductases EC 1.7.-
Oxygen S88TT14065

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Wellcome Trust
Pays : United Kingdom

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Auteurs

Yu Wan (Y)

NIHR Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance, Department of Infectious Disease, Imperial College London, London, UK.
HCAI, Fungal, AMR, AMU and Sepsis Division, UK Health Security Agency, London, UK.

Akshay Sabnis (A)

Centre for Bacterial Resistance Biology, Imperial College London, London, UK.

Zaynab Mumin (Z)

Reference Services Division, National Infection Service, UK Health Security Agency, London, UK.

Isabelle Potterill (I)

Reference Services Division, National Infection Service, UK Health Security Agency, London, UK.

Elita Jauneikaite (E)

NIHR Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance, Department of Infectious Disease, Imperial College London, London, UK.
Department of Infectious Disease Epidemiology, School of Public Health, Imperial College London, London, UK.
MRC Centre for Global Infectious Disease Analysis, School of Public Health, Imperial College London, London, UK.

Colin S Brown (CS)

NIHR Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance, Department of Infectious Disease, Imperial College London, London, UK.
HCAI, Fungal, AMR, AMU and Sepsis Division, UK Health Security Agency, London, UK.

Matthew J Ellington (MJ)

NIHR Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance, Department of Infectious Disease, Imperial College London, London, UK.
HCAI, Fungal, AMR, AMU and Sepsis Division, UK Health Security Agency, London, UK.

Andrew Edwards (A)

Centre for Bacterial Resistance Biology, Imperial College London, London, UK.

Shiranee Sriskandan (S)

NIHR Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance, Department of Infectious Disease, Imperial College London, London, UK.
Centre for Bacterial Resistance Biology, Imperial College London, London, UK.

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Classifications MeSH