Monte Carlo simulation of water diffusion through cardiac tissue models.


Journal

Medical engineering & physics
ISSN: 1873-4030
Titre abrégé: Med Eng Phys
Pays: England
ID NLM: 9422753

Informations de publication

Date de publication:
10 2023
Historique:
received: 22 10 2022
revised: 13 05 2023
accepted: 22 06 2023
medline: 23 10 2023
pubmed: 7 9 2023
entrez: 6 9 2023
Statut: ppublish

Résumé

Monte Carlo diffusion simulations are commonly used to establish a reliable ground truth of tissue microstructure, including for the validation of diffusion-weighted MRI. However, selecting simulation parameters is challenging and affects validity and reproducibility. We conducted experiments to investigate critical conditions in Monte Carlo simulations, such as tissue representation complexity, simulated molecules, update duration, and compartment size. Results show significant changes in microstructure characteristics when parameters are altered, emphasizing the importance of careful control for a reliable ground truth.

Identifiants

pubmed: 37673779
pii: S1350-4533(23)00068-1
doi: 10.1016/j.medengphy.2023.104013
pii:
doi:

Substances chimiques

Water 059QF0KO0R

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

104013

Informations de copyright

Copyright © 2023 IPEM. Published by Elsevier Ltd. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest The authors declare no conflict of interest.

Auteurs

Yuhan Jing (Y)

Univ Lyon, INSA-Lyon, Université Claude Bernard Lyon 1, UJM-Saint Etienne, CNRS, Inserm, CREATIS UMR 5220, U1294, 21 Avenue Jean Capelle, Lyon, 69621, France.

Isabelle E Magnin (IE)

Univ Lyon, INSA-Lyon, Université Claude Bernard Lyon 1, UJM-Saint Etienne, CNRS, Inserm, CREATIS UMR 5220, U1294, 21 Avenue Jean Capelle, Lyon, 69621, France.

Carole Frindel (C)

Univ Lyon, INSA-Lyon, Université Claude Bernard Lyon 1, UJM-Saint Etienne, CNRS, Inserm, CREATIS UMR 5220, U1294, 21 Avenue Jean Capelle, Lyon, 69621, France. Electronic address: Carole.Frindel@creatis.insa-lyon.fr.

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Classifications MeSH