The Functional Role of Myogenin in Cardiomyoblast H9c2 Cells Treated with High Glucose and Palmitic Acid: Insights into No-Rejection Heart Transplantation.
cell differentiation
myogenin
palmitic acid
reactive oxygen species
transplantation
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
22 Aug 2023
22 Aug 2023
Historique:
received:
25
07
2023
revised:
14
08
2023
accepted:
19
08
2023
medline:
11
9
2023
pubmed:
9
9
2023
entrez:
9
9
2023
Statut:
epublish
Résumé
Various pathological alterations, including lipid-deposition-induced comparative cardiac lipotoxicity, contribute to cardiac aging in the failing heart. A decline in endogenous myogenin proteins can lead to the reversal of muscle cell differentiation and the creation of mononucleated muscle cells. Myogenin may be a specific regulator of adaptive responses to avoid pathological hypertrophy in the heart. Hence, it is important to understand the regulation of myogenin expression and functions in response to exposure to varied stresses. In this study, we first examined and verified the cytotoxic effect of palmitic acid on H9c2 cells. The reduction in
Identifiants
pubmed: 37685838
pii: ijms241713031
doi: 10.3390/ijms241713031
pmc: PMC10487901
pii:
doi:
Substances chimiques
Palmitic Acid
2V16EO95H1
Myogenin
0
methoxy-morpholinyl-doxorubicin
108852-90-0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : National Science and Technology Council, Taiwan
ID : NSTC-112-2314-B-016-052 to P-S Hsu
Organisme : Tri-Service General Hospital, Taiwan
ID : TSGH-A-112007 to P-S Hsu
Références
Int J Mol Sci. 2022 Dec 21;24(1):
pubmed: 36613541
Cell Reprogram. 2014 Oct;16(5):324-30
pubmed: 25090621
Bioessays. 1995 Mar;17(3):203-9
pubmed: 7748174
Nutr Rev. 2020 Jun 1;78(6):474-485
pubmed: 31841151
Compr Physiol. 2013 Oct;3(4):1645-87
pubmed: 24265241
J Mol Med (Berl). 2009 Nov;87(11):1053-60
pubmed: 19705082
Cell Death Dis. 2018 May 11;9(5):568
pubmed: 29752433
Nutrients. 2020 Jan 14;12(1):
pubmed: 31947528
Metabolism. 2021 Feb;115:154453
pubmed: 33249043
ScientificWorldJournal. 2013;2013:593267
pubmed: 23431256
Circulation. 2021 Dec 7;144(23):e472-e487
pubmed: 34724806
J Mol Cell Biol. 2023 Mar 29;14(10):
pubmed: 36472556
J Biol Chem. 1999 Oct 8;274(41):29063-70
pubmed: 10506158
Biosci Rep. 2013 Dec 03;33(6):
pubmed: 24188104
Nat Metab. 2021 May;3(5):588-589
pubmed: 34031593
Circ Res. 1991 Dec;69(6):1476-86
pubmed: 1683272
Innovation (Camb). 2021 Jul 01;2(3):100141
pubmed: 34557778
Exp Cell Res. 1976 Mar 15;98(2):367-81
pubmed: 943302
Life (Basel). 2021 Feb 19;11(2):
pubmed: 33669781
Front Pharmacol. 2022 Mar 23;13:809157
pubmed: 35401162
J Biol Chem. 2003 Nov 21;278(47):47119-28
pubmed: 12944397
Front Physiol. 2017 Nov 08;8:902
pubmed: 29167646
Methods Mol Biol. 2019;1896:21-29
pubmed: 30474836
Biochem Biophys Res Commun. 2015 Mar 20;458(4):790-5
pubmed: 25686491
Cell Death Differ. 2015 Apr;22(4):560-73
pubmed: 25501595
Front Physiol. 2021 Apr 29;12:669497
pubmed: 33995129
PLoS One. 2012;7(1):e29896
pubmed: 22235349
J Physiol. 2020 Jul;598(14):2977-2993
pubmed: 30869158
Semin Cell Dev Biol. 2017 Dec;72:10-18
pubmed: 29127045
Carcinogenesis. 2014 May;35(5):1003-11
pubmed: 24318997
Trends Biochem Sci. 2014 Apr;39(4):159-69
pubmed: 24630600
Nucleic Acids Res. 2017 Sep 6;45(15):8785-8805
pubmed: 28575289
Oncotarget. 2015 Nov 10;6(35):37443-57
pubmed: 26452256
Transplantation. 2023 Jan 1;107(1):27-44
pubmed: 36508644
J Mol Cell Cardiol. 2000 Mar;32(3):511-9
pubmed: 10731449
J Cell Biol. 1996 Feb;132(4):657-66
pubmed: 8647896
Elife. 2020 Oct 01;9:
pubmed: 33001028
Biochem Biophys Res Commun. 2020 May 21;526(1):122-127
pubmed: 32199617
Circulation. 2010 Dec 7;122(23):2378-87
pubmed: 21098446
Cells. 2022 Apr 29;11(9):
pubmed: 35563799
Aging (Albany NY). 2020 Nov 2;12(21):21446-21468
pubmed: 33136552
Cell Syst. 2015 Dec 23;1(6):417-425
pubmed: 26771021
Am J Med. 1991 Sep 30;91(3C):14S-22S
pubmed: 1928205
Mol Med Rep. 2013 Mar;7(3):855-61
pubmed: 23338747
Am J Cardiovasc Drugs. 2019 Jun;19(3):249-257
pubmed: 30767126
Biochem Biophys Res Commun. 2021 May 7;552:84-90
pubmed: 33743352
J Cell Biol. 2014 Jun 23;205(6):829-46
pubmed: 24934157
Nutr Metab Cardiovasc Dis. 2017 Dec;27(12):1060-1080
pubmed: 29174025
Int J Mol Sci. 2021 Apr 02;22(7):
pubmed: 33918312
J Biol Chem. 2014 Feb 14;289(7):3923-35
pubmed: 24385428
Front Nutr. 2022 Mar 23;9:861664
pubmed: 35399673