Association between Human Leukocyte Antigen and End-Stage Renal Disease in Patients from Transylvania, Romania.
allele frequency
end-stage renal disease
haplotype frequency
human leukocyte antigen
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
29 Aug 2023
29 Aug 2023
Historique:
received:
30
06
2023
revised:
09
08
2023
accepted:
25
08
2023
medline:
11
9
2023
pubmed:
9
9
2023
entrez:
9
9
2023
Statut:
epublish
Résumé
End-stage renal disease (ESRD) is the final stage of chronic kidney disease. This study explored the association between human leukocyte antigen (HLA) and ESRD. The interaction between genetic and environmental factors may also play a role in the development of ESRD. The study included 2392 ESRD patients who were awaiting renal transplantation. Blood samples were genotyped by SSOP and SSP-PCR methods. Multivariate logistic regression analysis showed that HLA-A*11 (
Identifiants
pubmed: 37686189
pii: ijms241713383
doi: 10.3390/ijms241713383
pmc: PMC10488296
pii:
doi:
Substances chimiques
HLA-DRB1 Chains
0
Histocompatibility Antigens
0
HLA Antigens
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
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