Multifaceted control of T cell differentiation by STIM1.

ORAI1 Protein / metabolism Stromal Interaction Molecule 1 / metabolism Cell Membrane / metabolism Cell Differentiation Calcium / metabolism Calcium Signaling / physiology
STIM1 T cells calcium differentiation mitochondria

Journal

Trends in biochemical sciences
ISSN: 0968-0004
Titre abrégé: Trends Biochem Sci
Pays: England
ID NLM: 7610674

Informations de publication

Date de publication:
Dec 2023
Historique:
received: 15 03 2023
revised: 08 08 2023
accepted: 18 08 2023
medline: 13 11 2023
pubmed: 12 9 2023
entrez: 11 9 2023
Statut: ppublish

Résumé

In T cells, stromal interaction molecule (STIM) and Orai are dispensable for conventional T cell development, but critical for activation and differentiation. This review focuses on novel STIM-dependent mechanisms for control of Ca

Identifiants

DOI: 10.1016/j.tibs.2023.08.006 PMID: 37696713
pubmed: 37696713
pii: S0968-0004(23)00209-8
doi: 10.1016/j.tibs.2023.08.006
pii:
doi:

Substances chimiques

ORAI1 Protein 0
Stromal Interaction Molecule 1 0
Calcium SY7Q814VUP

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

1083-1097

Informations de copyright

Copyright © 2023 Elsevier Ltd. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of interests No interests are declared.

Auteurs

Scott Gross (S)

Fels Cancer Institute for Personalized Medicine, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, 19140, USA.

Lauren Womer (L)

Fels Cancer Institute for Personalized Medicine, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, 19140, USA.

Dietmar J Kappes (DJ)

Fox Chase Cancer Center, Philadelphia, PA 19111, USA.

Jonathan Soboloff (J)

Fels Cancer Institute for Personalized Medicine, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, 19140, USA; Department of Cancer and Cellular Biology, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, 19140, USA. Electronic address: soboloff@temple.edu.

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Classifications MeSH

questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Protéines de transport membranaire › Canaux ioniques › Canaux calciques › Canaux calciques activés par la libération de calcium › Protéine ORAI1 › Multifaceted control of T cell differentiation...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Molécules d'interaction stromale › Molécule-1 d'interaction stromale › Multifaceted control of T cell differentiation...
questionsmedicales.fr › Cellules › Structures cellulaires › Membrane cellulaire › Multifaceted control of T cell differentiation...
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Différenciation cellulaire › Multifaceted control of T cell differentiation...
questionsmedicales.fr › Facteurs biologiques › Facteurs de la coagulation sanguine › Calcium › Multifaceted control of T cell differentiation...
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Transduction du signal › Systèmes de seconds messagers › Signalisation calcique › Multifaceted control of T cell differentiation...