Diverse applications and development of aptamer detection technology.
Application of aptasensor
Aptamer
Aptasensor
Detection technology
Journal
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry
ISSN: 1348-2246
Titre abrégé: Anal Sci
Pays: Switzerland
ID NLM: 8511078
Informations de publication
Date de publication:
Oct 2023
Oct 2023
Historique:
received:
22
02
2023
accepted:
04
06
2023
medline:
27
9
2023
pubmed:
13
9
2023
entrez:
12
9
2023
Statut:
ppublish
Résumé
Aptamers have received extensive attention in recent years because of their advantages of high specificity, high sensitivity and low immunogenicity. Aptamers can perform almost all functions of antibodies through the combination of spatial structure and target, which are called "chemical antibodies". At present, aptamers have been widely used in cell imaging, new drug development, disease treatment, microbial detection and other fields. Due to the diversity of modifications, aptamers can be combined with different detection technologies to construct aptasensors. This review focuses on the diversity of aptamers in the field of detection and the development of aptamer-based detection technology and proposes new challenges for aptamers in this field.
Identifiants
pubmed: 37700097
doi: 10.1007/s44211-023-00409-2
pii: 10.1007/s44211-023-00409-2
doi:
Substances chimiques
Antibodies
0
Oligonucleotides
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
1627-1641Informations de copyright
© 2023. The Author(s), under exclusive licence to The Japan Society for Analytical Chemistry.
Références
A.D. Ellington, J.W. Szostak, In vitro selection of RNA molecules that bind specific ligands. Nature (1990). https://doi.org/10.1038/346818a0
doi: 10.1038/346818a0
pubmed: 2215683
C. Tuerk, L. Gold, Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase. Science (1990). https://doi.org/10.1126/science.2200121
doi: 10.1126/science.2200121
pubmed: 2200121
A.D. Ellington, J.W. Szostak, Selection in vitro of single-stranded DNA molecules that fold into specific ligand-binding structures. Nature (1992). https://doi.org/10.1038/355850a0
doi: 10.1038/355850a0
pubmed: 1538766
T. Hermann, E. Westhof, Non-Watson-Crick base pairs in RNA-protein recognition. Chem. Biol. (1999). https://doi.org/10.1016/s1074-5521(00)80003-4
doi: 10.1016/s1074-5521(00)80003-4
pubmed: 10631510
C. Liang, D. Li, G. Zhang, H. Li, N. Shao, Z. Liang, L. Zhang, A. Lu, G. Zhang, Comparison of the methods for generating single-stranded DNA in SELEX. Analyst (2015). https://doi.org/10.1039/c5an00244c
doi: 10.1039/c5an00244c
pubmed: 26609548
pmcid: 4837892
J. Zhou, J. Rossi, Aptamers as targeted therapeutics: current potential and challenges. Nat. Rev. Drug Discov. (2017). https://doi.org/10.1038/nrd.2016.199
doi: 10.1038/nrd.2016.199
pubmed: 28450742
E.S. Gragoudas, A.P. Adamis, E.T. Cunningham Jr., M. Feinsod, D.R. Guyer, Group VISiONCT, Pegaptanib for neovascular age-related macular degeneration. N. Engl. J. Med. (2004). https://doi.org/10.1056/NEJMoa042760
doi: 10.1056/NEJMoa042760
pubmed: 15625332
L. Gryziewicz, Regulatory aspects of drug approval for macular degeneration. Adv. Drug Deliv. Rev. (2005). https://doi.org/10.1016/j.addr.2005.09.009
doi: 10.1016/j.addr.2005.09.009
pubmed: 16316706
X. Liu, G. Cao, H. Ding, D. Zhang, G. Yang, N. Liu, M. Fan, B. Shen, N. Shao, Screening of functional antidotes of RNA aptamers against bovine thrombin. FEBS Lett. (2004). https://doi.org/10.1016/S0014-5793(04)00197-8
doi: 10.1016/S0014-5793(04)00197-8
pubmed: 15589827
pmcid: 1986658
F. He, N. Wen, D. Xiao, J. Yan, H. Xiong, S. Cai, Z. Liu, Y. Liu, Aptamer-based targeted drug delivery systems: current potential and challenges. Curr. Med. Chem. (2020). https://doi.org/10.2174/0929867325666181008142831
doi: 10.2174/0929867325666181008142831
pubmed: 32081105
S.M. Nimjee, R.R. White, R.C. Becker, B.A. Sullenger, Aptamers as therapeutics. Annu. Rev. Pharmacol. Toxicol. (2017). https://doi.org/10.1146/annurev-pharmtox-010716-104558
doi: 10.1146/annurev-pharmtox-010716-104558
pubmed: 28061688
pmcid: 6035745
M.J. Duffy, Role of tumor markers in patients with solid cancers: a critical review. Eur. J. Intern. Med. (2007). https://doi.org/10.1016/j.ejim.2006.12.001
doi: 10.1016/j.ejim.2006.12.001
pubmed: 17449388
F. Zhang, Z. Liu, Y. Han, L. Fan, Y. Guo, Sandwich electrochemical carcinoembryonic antigen aptasensor based on signal amplification of polydopamine functionalized graphene conjugate Pd-Pt nanodendrites. Bioelectrochemistry (2021). https://doi.org/10.1016/j.bioelechem.2021.107947
doi: 10.1016/j.bioelechem.2021.107947
pubmed: 34974371
pmcid: 8492042
X. Liu, Y. Zhao, F. Li, Nucleic acid-functionalized metal-organic framework for ultrasensitive immobilization-free photoelectrochemical biosensing. Biosens. Bioelectron. (2021). https://doi.org/10.1016/j.bios.2020.112832
doi: 10.1016/j.bios.2020.112832
pubmed: 35134684
pmcid: 8718887
J. Zhang, D. Tang, 4-Nitrophenol-loaded magnetic mesoporous silica hybrid materials for spectrometric aptasensing of carcinoembryonic antigen. Micromachines (Basel) (2021). https://doi.org/10.3390/mi12101138
doi: 10.3390/mi12101138
pubmed: 35056234
pmcid: 8540298
Y. Ji, J. Guo, B. Ye, G. Peng, C. Zhang, L. Zou, An ultrasensitive carcinoembryonic antigen electrochemical aptasensor based on 3D DNA nanoprobe and Exo III. Biosens. Bioelectron. (2022). https://doi.org/10.1016/j.bios.2021.113741
doi: 10.1016/j.bios.2021.113741
pubmed: 36525707
pmcid: 9476360
Q. Pan, C.O.K. Law, M.M.H. Yung, K.C. Han, Y.L. Pon, T.C.K. Lau, Novel RNA aptamers targeting gastrointestinal cancer biomarkers CEA, CA50 and CA72-4 with superior affinity and specificity. PLoS One (2018). https://doi.org/10.1371/journal.pone.0198980
doi: 10.1371/journal.pone.0198980
pubmed: 30596713
pmcid: 6312390
Y.J. Lee, S.R. Han, N.Y. Kim, S.H. Lee, J.S. Jeong, S.W. Lee, An RNA aptamer that binds carcinoembryonic antigen inhibits hepatic metastasis of colon cancer cells in mice. Gastroenterology (2012). https://doi.org/10.1053/j.gastro.2012.03.039
doi: 10.1053/j.gastro.2012.03.039
pubmed: 23234302
pmcid: 3563525
Z. Mitri, T. Constantine, R. O’Regan, The HER2 receptor in breast cancer: pathophysiology, clinical use, and new advances in therapy. Chemother. Res. Pract. (2012). https://doi.org/10.1155/2012/743193
doi: 10.1155/2012/743193
pubmed: 23320171
pmcid: 3539433
G. Mendoza, A. Portillo, J. Olmos-Soto, Accurate breast cancer diagnosis through real-time PCR her-2 gene quantification using immunohistochemically-identified biopsies. Oncol. Lett. (2013). https://doi.org/10.3892/ol.2012.984
doi: 10.3892/ol.2012.984
pubmed: 23759995
pmcid: 3678573
W.J. Wang, Y.Y. Lei, J.H. Mei, C.L. Wang, Recent progress in HER2 associated breast cancer. Asian. Pac. J. Cancer Prev. (2015). https://doi.org/10.7314/apjcp.2015.16.7.2591
doi: 10.7314/apjcp.2015.16.7.2591
pubmed: 26745136
Y. Chai, X. Li, M. Yang, Aptamer based determination of the cancer biomarker HER2 by using phosphate-functionalized MnO(2) nanosheets as the electrochemical probe. Mikrochim. Acta. (2019). https://doi.org/10.1007/s00604-019-3412-y
doi: 10.1007/s00604-019-3412-y
pubmed: 31853657
Y. Zhang, N. Li, Y. Xu, P. Lu, N. Qi, M. Yang, C. Hou, D. Huo, An ultrasensitive dual-signal aptasensor based on functionalized Sb@ZIF-67 nanocomposites for simultaneously detect multiple biomarkers. Biosens. Bioelectron. (2022). https://doi.org/10.1016/j.bios.2022.114508
doi: 10.1016/j.bios.2022.114508
pubmed: 36603286
pmcid: 10143284
Y. Xu, Y. Zhang, N. Li, M. Yang, T. Xiang, D. Huo, Z. Qiu, L. Yang, C. Hou, An ultra-sensitive dual-signal ratiometric electrochemical aptasensor based on functionalized MOFs for detection of HER2. Bioelectrochemistry (2022). https://doi.org/10.1016/j.bioelechem.2022.108272
doi: 10.1016/j.bioelechem.2022.108272
pubmed: 36608370
pmcid: 9130314
N. Zhou, F. Su, Z. Li, X. Yan, C. Zhang, B. Hu, L. He, M. Wang, Z. Zhang, Gold nanoparticles conjugated to bimetallic manganese(II) and iron(II) Prussian Blue analogues for aptamer-based impedimetric determination of the human epidermal growth factor receptor-2 and living MCF-7 cells. Mikrochim. Acta. (2019). https://doi.org/10.1007/s00604-018-3184-9
doi: 10.1007/s00604-018-3184-9
pubmed: 31853650
J. Song, Development of Electrochemical Aptamer Biosensor for Tumor Marker MUC1 Determination. Int J. Electrochem. Sci. (2017). https://doi.org/10.20964/2017.06.46
doi: 10.20964/2017.06.46
A. Fragoso, D. Latta, N. Laboria, F. von Germar, T.E. Hansen-Hagge, W. Kemmner, C. Gartner, R. Klemm, K.S. Drese, C.K. O’Sullivan, Integrated microfluidic platform for the electrochemical detection of breast cancer markers in patient serum samples. Lab. Chip. (2011). https://doi.org/10.1039/c0lc00398k
doi: 10.1039/c0lc00398k
pubmed: 21120243
G. Zhang, Z. Liu, L. Fan, Y. Han, Y. Guo, A novel dual signal and label-free electrochemical aptasensor for mucin 1 based on hemin/graphene@PdPtNPs. Biosens. Bioelectron. (2020). https://doi.org/10.1016/j.bios.2020.112785
doi: 10.1016/j.bios.2020.112785
pubmed: 33450611
pmcid: 10510655
M. Pan, J. Cai, S. Li, L. Xu, W. Ma, C. Xu, H. Kuang, Aptamer-gated ion channel for ultrasensitive mucin 1 detection. Anal. Chem. (2021). https://doi.org/10.1021/acs.analchem.0c04137
doi: 10.1021/acs.analchem.0c04137
pubmed: 34962759
pmcid: 8787799
M. Li, X. Guo, H. Li, X. Zuo, R. Hao, H. Song, A. Aldalbahi, Z. Ge, J. Li et al., Epitope binning assay using an electron transfer-modulated aptamer sensor. ACS Appl. Mater. Interfaces (2018). https://doi.org/10.1021/acsami.7b17324
doi: 10.1021/acsami.7b17324
pubmed: 30574778
pmcid: 9703972
B. Huang, X.P. Liu, J.S. Chen, C.J. Mao, H.L. Niu, B.K. Jin, Electrochemiluminescence immunoassay for the prostate-specific antigen by using a CdS/chitosan/g-C(3)N(4) nanocomposite. Mikrochim. Acta. (2020). https://doi.org/10.1007/s00604-020-4125-y
doi: 10.1007/s00604-020-4125-y
pubmed: 33201322
J. Zhao, J. Wang, Y. Liu, X.X. Han, B. Xu, Y. Ozaki, B. Zhao, Detection of prostate cancer biomarkers via a SERS-based aptasensor. Biosens. Bioelectron. (2022). https://doi.org/10.1016/j.bios.2022.114660
doi: 10.1016/j.bios.2022.114660
pubmed: 36621082
pmcid: 9759211
J. Man, J. Dong, Y. Wang, L. He, S. Yu, F. Yu, J. Wang, Y. Tian, L. Liu et al., Simultaneous detection of VEGF and CEA by time-resolved chemiluminescence enzyme-linked aptamer assay. Int. J. Nanomed. (2020). https://doi.org/10.2147/IJN.S286317
doi: 10.2147/IJN.S286317
L. Qi, S. Liu, Y. Jiang, J.M. Lin, L. Yu, Q. Hu, Simultaneous detection of multiple tumor markers in blood by functional liquid crystal sensors assisted with target-induced dissociation of aptamer. Anal. Chem. (2020). https://doi.org/10.1021/acs.analchem.9b05317
doi: 10.1021/acs.analchem.9b05317
pubmed: 33369403
pmcid: 7670281
D. Shangguan, Y. Li, Z. Tang, Z.C. Cao, H.W. Chen, P. Mallikaratchy, K. Sefah, C.J. Yang, W. Tan, Aptamers evolved from live cells as effective molecular probes for cancer study. Proc. Natl. Acad.Sci. USA (2006). https://doi.org/10.1073/pnas.0602615103
doi: 10.1073/pnas.0602615103
pubmed: 16873550
pmcid: 1567664
D.A. Daniels, H. Chen, B.J. Hicke, K.M. Swiderek, L. Gold, A tenascin-C aptamer identified by tumor cell SELEX: systematic evolution of ligands by exponential enrichment. Proc. Natl. Acad. Sci. USA (2003). https://doi.org/10.1073/pnas.2136683100
doi: 10.1073/pnas.2136683100
pubmed: 14676325
pmcid: 307582
K. Sefah, D. Shangguan, X. Xiong, M.B. O’Donoghue, W. Tan, Development of DNA aptamers using Cell-SELEX. Nat. Protoc. (2010). https://doi.org/10.1038/nprot.2010.66
doi: 10.1038/nprot.2010.66
pubmed: 20539292
B. J. Hicke, A. W. Stephens, T. Gould, Y. F. Chang, C. K. Lynott, J. Heil, S. Borkowski, C. S. Hilger, G. Cook, S. Warren, P. G. Schmidt, Tumor targeting by an aptamer. J. Nucl. Med. 47(4):668–678. (2006)
H. Shi, X. He, K. Wang, X. Wu, X. Ye, Q. Guo, W. Tan, Z. Qing, X. Yang, B. Zhou, Activatable aptamer probe for contrast-enhanced in vivo cancer imaging based on cell membrane protein-triggered conformation alteration. Proc. Natl. Acad. Sci. USA (2011). https://doi.org/10.1073/pnas.1016197108
doi: 10.1073/pnas.1016197108
pubmed: 22203992
pmcid: 3258620
G. Zhu, J. Zheng, E. Song, M. Donovan, K. Zhang, C. Liu, W. Tan, Self-assembled, aptamer-tethered DNA nanotrains for targeted transport of molecular drugs in cancer theranostics. Proc. Natl. Acad. Sci. USA (2013). https://doi.org/10.1073/pnas.1220817110
doi: 10.1073/pnas.1220817110
pubmed: 24379378
pmcid: 3910645
D. Shangguan, L. Meng, Z.C. Cao, Z. Xiao, X. Fang, Y. Li, D. Cardona, R.P. Witek, C. Liu, W. Tan, Identification of liver cancer-specific aptamers using whole live cells. Anal. Chem. (2008). https://doi.org/10.1021/ac701962v
doi: 10.1021/ac701962v
pubmed: 18177018
X. Wu, Z. Zhao, H. Bai, T. Fu, C. Yang, X. Hu, Q. Liu, C. Champanhac, I.T. Teng et al., DNA aptamer selected against pancreatic ductal adenocarcinoma for in vivo imaging and clinical tissue recognition. Theranostics (2015). https://doi.org/10.7150/thno.11938
doi: 10.7150/thno.11938
pubmed: 26379786
pmcid: 4568448
L. Li, J. Wan, X. Wen, Q. Guo, H. Jiang, J. Wang, Y. Ren, K. Wang, Identification of a new DNA aptamer by tissue-SELEX for cancer recognition and imaging. Anal. Chem. (2021). https://doi.org/10.1021/acs.analchem.1c01445
doi: 10.1021/acs.analchem.1c01445
pubmed: 34968407
pmcid: 8482318
X. Ren, J. Li, X. Wu, J. Zhao, Q. Yang, X. Lou, A highly specific aptamer probe targeting PD-L1 in tumor tissue sections: mutation favors specificity. Anal. Chim. Acta. (2021). https://doi.org/10.1016/j.aca.2021.339066
doi: 10.1016/j.aca.2021.339066
pubmed: 35057924
L. Li, X. Yang, K. Li, G. Zhang, Y. Ma, B. Cai, S. Li, H. Ding, J. Deng et al., d-/l-Isothymidine incorporation in the core sequence of aptamer BC15 enhanced its binding affinity to the hnRNP A1 protein. Org. Biomol. Chem. (2018). https://doi.org/10.1039/c8ob01454j
doi: 10.1039/c8ob01454j
pubmed: 30525162
pmcid: 6051884
H. Li, L. Guo, A. Huang, H. Xu, X. Liu, H. Ding, J. Dong, J. Li, C. Wang et al., Nanoparticle-conjugated aptamer targeting hnRNP A2/B1 can recognize multiple tumor cells and inhibit their proliferation. Biomaterials (2015). https://doi.org/10.1016/j.biomaterials.2015.06.013
doi: 10.1016/j.biomaterials.2015.06.013
pubmed: 26774562
pmcid: 4715930
Y. Yang, Y. Fu, H. Su, L. Mao, M. Chen, Sensitive detection of MCF-7 human breast cancer cells by using a novel DNA-labeled sandwich electrochemical biosensor. Biosens. Bioelectron. (2018). https://doi.org/10.1016/j.bios.2018.09.062
doi: 10.1016/j.bios.2018.09.062
pubmed: 30634075
pmcid: 7126597
B. Hong, Y. Zu, Detecting circulating tumor cells: current challenges and new trends. Theranostics (2013). https://doi.org/10.7150/thno.5195
doi: 10.7150/thno.5195
pubmed: 24312158
pmcid: 3841339
J. Zhang, S. Li, F. Liu, L. Zhou, N. Shao, X. Zhao, SELEX aptamer used as a probe to detect circulating tumor cells in peripheral blood of pancreatic cancer patients. PLoS One (2015). https://doi.org/10.1371/journal.pone.0121920
doi: 10.1371/journal.pone.0121920
pubmed: 26720630
pmcid: 4697838
H. Shen, W. Deng, Y. He, X. Li, J. Song, R. Liu, H. Liu, G. Yang, L. Li, Ultrasensitive aptasensor for isolation and detection of circulating tumor cells based on CeO(2)@Ir nanorods and DNA walker. Biosens. Bioelectron. (2020). https://doi.org/10.1016/j.bios.2020.112516
doi: 10.1016/j.bios.2020.112516
pubmed: 33422922
pmcid: 7836976
Z. Zhang, C. Tang, L. Zhao, L. Xu, W. Zhou, Z. Dong, Y. Yang, Q. Xie, X. Fang, Aptamer-based fluorescence polarization assay for separation-free exosome quantification. Nanoscale (2019). https://doi.org/10.1039/c9nr01589b
doi: 10.1039/c9nr01589b
pubmed: 31845951
pmcid: 6792296
H. Chen, C. Huang, Y. Wu, N. Sun, C. Deng, Exosome metabolic patterns on aptamer-coupled polymorphic carbon for precise detection of early gastric cancer. ACS Nano. (2022). https://doi.org/10.1021/acsnano.2c05355
doi: 10.1021/acsnano.2c05355
pubmed: 36584240
pmcid: 9901196
C.L. Esposito, C. Quintavalle, F. Ingenito, D. Rotoli, G. Roscigno, S. Nuzzo, R. Thomas, S. Catuogno, V. de Franciscis, G. Condorelli, Identification of a novel RNA aptamer that selectively targets breast cancer exosomes. Mol. Ther. Nucleic Acids (2021). https://doi.org/10.1016/j.omtn.2021.01.012
doi: 10.1016/j.omtn.2021.01.012
pubmed: 33614245
pmcid: 7868932
A. Molinero-Fernandez, M.A. Lopez, A. Escarpa, Electrochemical microfluidic micromotors-based immunoassay for C-reactive protein determination in preterm neonatal samples with sepsis suspicion. Anal. Chem. (2020). https://doi.org/10.1021/acs.analchem.9b05384
doi: 10.1021/acs.analchem.9b05384
pubmed: 32154703
A.T.E. Vilian, W. Kim, B. Park, S.Y. Oh, T. Kim, Y.S. Huh, C.K. Hwangbo, Y.K. Han, Efficient electron-mediated electrochemical biosensor of gold wire for the rapid detection of C-reactive protein: a predictive strategy for heart failure. Biosens. Bioelectron. (2019). https://doi.org/10.1016/j.bios.2019.111549
doi: 10.1016/j.bios.2019.111549
pubmed: 31400725
S. Huang, Z. Liu, Y. Yan, J. Chen, R. Yang, Q. Huang, M. Jin, L. Shui, Triple signal-enhancing electrochemical aptasensor based on rhomboid dodecahedra carbonized-ZIF(67) for ultrasensitive CRP detection. Biosens. Bioelectron. (2022). https://doi.org/10.1016/j.bios.2022.114129
doi: 10.1016/j.bios.2022.114129
pubmed: 36863194
pmcid: 9759211
V. Singh, Ultrasensitive quantum dot-coupled-surface plasmon microfluidic aptasensor array for serum insulin detection. Talanta (2020). https://doi.org/10.1016/j.talanta.2020.121314
doi: 10.1016/j.talanta.2020.121314
pubmed: 33379113
M. Yu, X. Zhang, X. Zhang, Q.U.A. Zahra, Z. Huang, Y. Chen, C. Song, M. Song, H. Jiang et al., An electrochemical aptasensor with N protein binding aptamer-complementary oligonucleotide as probe for ultra-sensitive detection of COVID-19. Biosens. Bioelectron. (2022). https://doi.org/10.1016/j.bios.2022.114436
doi: 10.1016/j.bios.2022.114436
pubmed: 36603284
pmcid: 9176179
C. Han, W. Li, Q. Li, W. Xing, H. Luo, H. Ji, X. Fang, Z. Luo, L. Zhang, CRISPR/Cas12a-Derived electrochemical aptasensor for ultrasensitive detection of COVID-19 nucleocapsid protein. Biosens. Bioelectron. (2022). https://doi.org/10.1016/j.bios.2021.113922
doi: 10.1016/j.bios.2021.113922
pubmed: 36603284
pmcid: 9610180
A. Kurmangali, K. Dukenbayev, D. Kanayeva, Sensitive detection of SARS-CoV-2 variants using an electrochemical impedance spectroscopy based aptasensor. Int. J. Mol. Sci. (2022). https://doi.org/10.3390/ijms232113138
doi: 10.3390/ijms232113138
pubmed: 36361926
pmcid: 9656073
C. Han, W. Xing, W. Li, X. Fang, J. Zhao, F. Ge, W. Ding, P. Qu, Z. Luo, L. Zhang, Aptamers dimerization inspired biomimetic clamp assay towards impedimetric SARS-CoV-2 antigen detection. Sens. Actuators B Chem. (2023). https://doi.org/10.1016/j.snb.2023.133387
doi: 10.1016/j.snb.2023.133387
pubmed: 36694572
pmcid: 9851723
R. Chen, L. Kan, F. Duan, L. He, M. Wang, J. Cui, Z. Zhang, Z. Zhang, Surface plasmon resonance aptasensor based on niobium carbide MXene quantum dots for nucleocapsid of SARS-CoV-2 detection. Mikrochim. Acta. (2021). https://doi.org/10.1007/s00604-021-04974-z
doi: 10.1007/s00604-021-04974-z
pubmed: 34971440
pmcid: 8412382
N. Cennamo, L. Pasquardini, F. Arcadio, L. Lunelli, L. Vanzetti, V. Carafa, L. Altucci, L. Zeni, SARS-CoV-2 spike protein detection through a plasmonic D-shaped plastic optical fiber aptasensor. Talanta (2021). https://doi.org/10.1016/j.talanta.2021.122532
doi: 10.1016/j.talanta.2021.122532
pubmed: 34215035
pmcid: 8133803
K. Ghanbari, M. Roushani, A. Azadbakht, Ultra-sensitive aptasensor based on a GQD nanocomposite for detection of hepatitis C virus core antigen. Anal. Biochem. (2017). https://doi.org/10.1016/j.ab.2017.07.016
doi: 10.1016/j.ab.2017.07.016
pubmed: 28728900
G. Kim, J. Kim, S.M. Kim, T. Kato, J. Yoon, S. Noh, E.Y. Park, C. Park, T. Lee, J.W. Choi, Fabrication of MERS-nanovesicle biosensor composed of multi-functional DNA aptamer/graphene-MoS(2) nanocomposite based on electrochemical and surface-enhanced Raman spectroscopy. Sens. Actuators B Chem. (2022). https://doi.org/10.1016/j.snb.2021.131060
doi: 10.1016/j.snb.2021.131060
pubmed: 36589904
pmcid: 9791791
J. Kang, G. Yeom, S.-J. Ha, M.-G. Kim, Development of a DNA aptamer selection method based on the heterogeneous sandwich form and its application in a colorimetric assay for influenza A virus detection. New J. Chem. (2019). https://doi.org/10.1039/c8nj06458j
doi: 10.1039/c8nj06458j
A. Kushwaha, Y. Takamura, K. Nishigaki, M. Biyani, Competitive non-SELEX for the selective and rapid enrichment of DNA aptamers and its use in electrochemical aptasensor. Sci. Rep. (2019). https://doi.org/10.1038/s41598-019-43187-6
doi: 10.1038/s41598-019-43187-6
pubmed: 31745130
pmcid: 6863836
H. Chen, S.G. Park, N. Choi, J.I. Moon, H. Dang, A. Das, S. Lee, D.G. Kim, L. Chen, J. Choo, SERS imaging-based aptasensor for ultrasensitive and reproducible detection of influenza virus A. Biosens. Bioelectron. (2020). https://doi.org/10.1016/j.bios.2020.112496
doi: 10.1016/j.bios.2020.112496
pubmed: 33429204
pmcid: 7834412
V.I. Kukushkin, N.M. Ivanov, A.A. Novoseltseva, A.S. Gambaryan, I.V. Yaminsky, A.M. Kopylov, E.G. Zavyalova, Highly sensitive detection of influenza virus with SERS aptasensor. PLoS One (2019). https://doi.org/10.1371/journal.pone.0216247
doi: 10.1371/journal.pone.0216247
pubmed: 31022287
pmcid: 6483365
A.K. Cheng, D. Sen, H.Z. Yu, Design and testing of aptamer-based electrochemical biosensors for proteins and small molecules. Bioelectrochemistry (2009). https://doi.org/10.1016/j.bioelechem.2009.04.007
doi: 10.1016/j.bioelechem.2009.04.007
pubmed: 19473883
S. Ranjbar, S. Shahrokhian, F. Nurmohammadi, Nanoporous gold as a suitable substrate for preparation of a new sensitive electrochemical aptasensor for detection of Salmonella typhimurium. Sens. Actuators B (2018). https://doi.org/10.1016/j.snb.2017.08.160
doi: 10.1016/j.snb.2017.08.160
M.R. Hasan, T. Pulingam, J.N. Appaturi, A.N. Zifruddin, S.J. Teh, T.W. Lim, F. Ibrahim, B.F. Leo, K.L. Thong, Carbon nanotube-based aptasensor for sensitive electrochemical detection of whole-cell Salmonella. Anal. Biochem. (2018). https://doi.org/10.1016/j.ab.2018.06.001
doi: 10.1016/j.ab.2018.06.001
pubmed: 29870692
N. Li, X. Huang, D. Sun, W. Yu, W. Tan, Z. Luo, Z. Chen, Dual-aptamer-based voltammetric biosensor for the Mycobacterium tuberculosis antigen MPT64 by using a gold electrode modified with a peroxidase loaded composite consisting of gold nanoparticles and a Zr(IV)/terephthalate metal-organic framework. Mikrochim. Acta. (2018). https://doi.org/10.1007/s00604-018-3081-2
doi: 10.1007/s00604-018-3081-2
pubmed: 30569376
D. Gou, G. Xie, Y. Li, X. Zhang, H. Chen, Voltammetric immunoassay for Mycobacterium tuberculosis secretory protein MPT64 based on a synergistic amplification strategy using rolling circle amplification and a gold electrode modified with graphene oxide, Fe(3)O(4) and Pt nanoparticles. Mikrochim. Acta. (2018). https://doi.org/10.1007/s00604-018-2972-6
doi: 10.1007/s00604-018-2972-6
pubmed: 30167897
J. Wang, X. Wu, C. Wang, N. Shao, P. Dong, R. Xiao, S. Wang, Magnetically assisted surface-enhanced raman spectroscopy for the detection of staphylococcus aureus based on aptamer recognition. ACS Appl. Mater. Interfaces (2015). https://doi.org/10.1021/acsami.5b06446
doi: 10.1021/acsami.5b06446
pubmed: 26709944
pmcid: 4924526
X. Ma, X. Lin, X. Xu, Z. Wang, Fabrication of gold/silver nanodimer SERS probes for the simultaneous detection of Salmonella typhimurium and Staphylococcus aureus. Mikrochim. Acta. (2021). https://doi.org/10.1007/s00604-021-04791-4
doi: 10.1007/s00604-021-04791-4
pubmed: 34878598
Y. Hou, N. Long, Q. Xu, Y. Li, P. Song, M. Yang, J. Wang, L. Zhou, P. Sheng, W. Kong, Development of a Nafion-MWCNTs and in-situ generated Au nanopopcorns dual-amplification electrochemical aptasensor for ultrasensitive detection of OTA. Food Chem (2023). https://doi.org/10.1016/j.foodchem.2022.134375
doi: 10.1016/j.foodchem.2022.134375
pubmed: 37742553
J. Zhang, X. Xu, Y. Qiang, Ultrasensitive electrochemical aptasensor for ochratoxin A detection using AgPt bimetallic nanoparticles decorated iron-porphyrinic metal-organic framework for signal amplification. Sens. Actuators B (2020). https://doi.org/10.1016/j.snb.2020.127964
doi: 10.1016/j.snb.2020.127964
S. Liu, Y. Huo, S. Deng, G. Li, S. Li, L. Huang, S. Ren, Z. Gao, A facile dual-mode aptasensor based on AuNPs@MIL-101 nanohybrids for ultrasensitive fluorescence and surface-enhanced Raman spectroscopy detection of tetrodotoxin. Biosens. Bioelectron. (2022). https://doi.org/10.1016/j.bios.2021.113891
doi: 10.1016/j.bios.2021.113891
pubmed: 36863194
pmcid: 9930661
X. Zhao, H. Shen, B. Huo, Y. Wang, Z. Gao, A novel bionic magnetic SERS aptasensor for the ultrasensitive detection of Deoxynivalenol based on :dual antennae” nano-silver. Biosens. Bioelectron. (2022). https://doi.org/10.1016/j.bios.2022.114383
doi: 10.1016/j.bios.2022.114383
pubmed: 36621082
pmcid: 9759211
H. Yan, B. He, L. Xie, X. Cao, A label-free electrochemical aptasensor based on NH(2)-MIL-235(Fe) for the sensitive detection of citrinin. Anal. Methods (2022). https://doi.org/10.1039/d2ay01243j
doi: 10.1039/d2ay01243j
pubmed: 36219148
S. Eissa, M. Zourob, Selection and characterization of DNA aptamers for electrochemical biosensing of carbendazim. Anal. Chem (2017). https://doi.org/10.1021/acs.analchem.6b04914
doi: 10.1021/acs.analchem.6b04914
pubmed: 28264568
C. Zhu, D. Liu, Z. Chen, L. Li, T. You, An ultra-sensitive aptasensor based on carbon nanohorns/gold nanoparticles composites for impedimetric detection of carbendazim at picogram levels. J. Coll. Interface Sci. (2019). https://doi.org/10.1016/j.jcis.2019.03.035
doi: 10.1016/j.jcis.2019.03.035
T. Liu, B. Lin, X. Yuan, Z. Chu, W. Jin, In situ fabrication of urchin-like Cu@carbon nanoneedles based aptasensor for ultrasensitive recognition of trace mercury ion. Biosens. Bioelectron. (2022). https://doi.org/10.1016/j.bios.2022.114147
doi: 10.1016/j.bios.2022.114147
pubmed: 36863194
pmcid: 9930661
Y. Wang, Y. Wang, F. Wang, H. Chi, G. Zhao, Y. Zhang, T. Li, Q. Wei, Electrochemical aptasensor based on gold modified thiol graphene as sensing platform and gold-palladium modified zirconium metal-organic frameworks nanozyme as signal enhancer for ultrasensitive detection of mercury ions. J. Coll. Interface Sci. (2022). https://doi.org/10.1016/j.jcis.2021.08.055
doi: 10.1016/j.jcis.2021.08.055
C. Tian, L. Zhao, J. Zhu, S. Zhang, Ultrasensitive detection of trace Hg(2+) by SERS aptasensor based on dual recycling amplification in water environment. J. Hazard Mater. (2021). https://doi.org/10.1016/j.jhazmat.2021.126251
doi: 10.1016/j.jhazmat.2021.126251
pubmed: 35236033
S. Qian, Y. Han, F. Xu, D. Feng, X. Yang, X. Wu, L. Hao, M. Yuan, A fast, sensitive, low-cost electrochemical paper-based chip for real-time simultaneous detection of cadmium (II) and lead (II) via aptamer. Talanta (2022). https://doi.org/10.1016/j.talanta.2022.123548
doi: 10.1016/j.talanta.2022.123548
pubmed: 36470013
M. Chen, M. Hassan, H. Li, Q. Chen, Fluorometric determination of lead(II) by using aptamer-functionalized upconversion nanoparticles and magnetite-modified gold nanoparticles. Mikrochim. Acta. (2020). https://doi.org/10.1007/s00604-019-4030-4
doi: 10.1007/s00604-019-4030-4
pubmed: 33201301
pmcid: 7581468
S.S. Baghbaderani, A. Noorbakhsh, Novel chitosan-Nafion composite for fabrication of highly sensitive impedimetric and colorimetric As(III) aptasensor. Biosens. Bioelectron. (2019). https://doi.org/10.1016/j.bios.2019.01.059
doi: 10.1016/j.bios.2019.01.059
pubmed: 30797108
L. Ma, D. Liao, Z. Zhao, J. Kou, H. Guo, X. Xiong, S. Man, Sensitive Small Molecule Aptasensing based on Hybridization Chain Reaction and CRISPR/Cas12a Using a Portable 3D-Printed Visualizer. ACS Sens. (2023). https://doi.org/10.1021/acssensors.2c02097
doi: 10.1021/acssensors.2c02097
pubmed: 37734027
X. Cheng, Y. Li, J. Kou, D. Liao, W. Zhang, L. Yin, S. Man, L. Ma, Novel non-nucleic acid targets detection strategies based on CRISPR/Cas toolboxes: a review. Biosens. Bioelectron. (2022). https://doi.org/10.1016/j.bios.2022.114559
doi: 10.1016/j.bios.2022.114559
pubmed: 36586150
pmcid: 9110061
C. Niu, C. Wang, F. Li, X. Zheng, X. Xing, C. Zhang, Aptamer assisted CRISPR-Cas12a strategy for small molecule diagnostics. Biosens. Bioelectron. (2021). https://doi.org/10.1016/j.bios.2021.113196
doi: 10.1016/j.bios.2021.113196
pubmed: 34781177
Y. Xiong, J. Zhang, Z. Yang, Q. Mou, Y. Ma, Y. Xiong, Y. Lu, Functional DNA regulated CRISPR-Cas12a sensors for point-of-care diagnostics of non-nucleic-acid targets. J. Am. Chem. Soc. (2020). https://doi.org/10.1021/jacs.9b09211
doi: 10.1021/jacs.9b09211
pubmed: 33373209
pmcid: 8161528
A.M. Yoshikawa, A. Rangel, T. Feagin, E.M. Chun, L. Wan, A. Li, L. Moeckl, D. Wu, M. Eisenstein et al., Discovery of indole-modified aptamers for highly specific recognition of protein glycoforms. Nat. Commun. (2021). https://doi.org/10.1038/s41467-021-26933-1
doi: 10.1038/s41467-021-26933-1
pubmed: 34876561
pmcid: 8651674
D. Shu, Y. Shu, F. Haque, S. Abdelmawla, P. Guo, Thermodynamically stable RNA three-way junction for constructing multifunctional nanoparticles for delivery of therapeutics. Nat. Nanotechnol. (2011). https://doi.org/10.1038/nnano.2011.105
doi: 10.1038/nnano.2011.105
pubmed: 21909084
pmcid: 3189281
B. Zhu, A. Hernandez, M. Tan, J. Wollenhaupt, S. Tabor, C.C. Richardson, Synthesis of 2’-Fluoro RNA by Syn5 RNA polymerase. Nucleic Acids Res. (2015). https://doi.org/10.1093/nar/gkv367
doi: 10.1093/nar/gkv367
pubmed: 26704980
pmcid: 4770227
G. Ying, X. Lu, J. Mei, Y. Zhang, J. Chen, X. Wang, Z. Ou, Y. Yi, A structure-activity relationship of a thrombin-binding aptamer containing LNA in novel sites. Bioorg. Med. Chem. (2019). https://doi.org/10.1016/j.bmc.2019.05.010
doi: 10.1016/j.bmc.2019.05.010
pubmed: 31171404
J. Chen, J. Wang, Z. Luo, X. Fang, L. He, J. Zhu, Z. Qurat Ul Ain, J. He, H. Ma et al., Productive screening of single aptamers with ddPCR. Analyst (2020). https://doi.org/10.1039/d0an00460j
doi: 10.1039/d0an00460j
pubmed: 33325918
pmcid: 7425357
N. Qiao, J. Li, X. Wu, D. Diao, J. Zhao, J. Li, X. Ren, X. Ding, D. Shangguan, X. Lou, Speeding up in vitro discovery of structure-switching aptamers via magnetic cross-linking precipitation. Anal. Chem. (2019). https://doi.org/10.1021/acs.analchem.9b00081
doi: 10.1021/acs.analchem.9b00081
pubmed: 31855414