Glycometabolic outcomes in adult type 1 diabetic patients switching to closed-loop systems.


Journal

Diabetes research and clinical practice
ISSN: 1872-8227
Titre abrégé: Diabetes Res Clin Pract
Pays: Ireland
ID NLM: 8508335

Informations de publication

Date de publication:
Oct 2023
Historique:
received: 27 07 2023
revised: 03 09 2023
accepted: 11 09 2023
medline: 30 10 2023
pubmed: 15 9 2023
entrez: 14 9 2023
Statut: ppublish

Résumé

This study aimed to evaluate glycometabolic outcomes in AID technology-naïve T1D patients after switching to Hybrid Closed Loop (HCL) and Advanced Hybrid Closed Loop (AHCL) systems. This was a 12-month, prospective, observational, two-center study on 54 type 1 diabetes (T1D) patients aged 19-65 years managed with multiple daily injections (MDI) or Continuous Subcutaneous Insulin Infusion (CSII) in open-loop to evaluate the superiority in terms of effectiveness and safety of Automated Insulin Delivery (AID) systems. HbA1c levels significantly improved at the end of the study. Time spent with glucose levels in target range (TIR AID-naïve T1D patients switching to HCL/AHCL systems have significantly and safely improved their glycometabolic outcomes with their high satisfaction with the new type of treatment.

Identifiants

pubmed: 37708979
pii: S0168-8227(23)00670-8
doi: 10.1016/j.diabres.2023.110907
pii:
doi:

Substances chimiques

Hypoglycemic Agents 0
Insulin 0
Blood Glucose 0

Types de publication

Observational Study Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

110907

Informations de copyright

Copyright © 2023 The Authors. Published by Elsevier B.V. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Auteurs

Giuseppe Papa (G)

Unit of Metabolic and Endocrine Disease, "Centro Catanese di Medicina e Chirurgia" Clinic, Catania, Italy.

Rossella Cannarella (R)

Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy; Glickman Urological & Kidney Institute, Cleveland Clinic Foundation, Cleveland, OH, USA.

Rosita A Condorelli (RA)

Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy.

Concetta Finocchiaro (C)

Unit of Metabolic and Endocrine Disease, "Centro Catanese di Medicina e Chirurgia" Clinic, Catania, Italy.

Aldo E Calogero (AE)

Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy. Electronic address: aldo.calogero@unict.it.

Sandro La Vignera (S)

Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy.

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Classifications MeSH