Area under the curve of tacrolimus using microsampling devices: towards precision medicine in solid organ transplantation?

Humans Tacrolimus / therapeutic use Immunosuppressive Agents / pharmacokinetics Precision Medicine Organ Transplantation Transplant Recipients Drug Monitoring / methods Area Under Curve
Calcineurin inhibitors Dried blood spots Drug monitoring Kidney transplantation Liver transplantation Pharmacokinetics

Journal

European journal of clinical pharmacology
ISSN: 1432-1041
Titre abrégé: Eur J Clin Pharmacol
Pays: Germany
ID NLM: 1256165

Informations de publication

Date de publication:
Nov 2023
Historique:
received: 24 05 2023
accepted: 13 09 2023
medline: 1 11 2023
pubmed: 19 9 2023
entrez: 19 9 2023
Statut: ppublish

Résumé

Therapeutic drug monitoring of tacrolimus using trough concentration (C Fifty-one transplant recipients benefited from a complete pharmacokinetic profile using a microsampling approach, and their 24-h AUC were calculated using the trapezoidal method. The correlation with C Weak correlations were found between 24-h AUC observed and the corresponding C Tacrolimus C

Identifiants

DOI: 10.1007/s00228-023-03566-5 PMID: 37725122
pubmed: 37725122
doi: 10.1007/s00228-023-03566-5
pii: 10.1007/s00228-023-03566-5
doi:

Substances chimiques

Tacrolimus WM0HAQ4WNM
Immunosuppressive Agents 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1549-1556

Informations de copyright

© 2023. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.

Références

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Auteurs

Aurélien Couette (A)

Univ Rennes, CHU Rennes, Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail)-UMR S 1085, F-35000 Rennes, France.

Camille Tron (C)

Univ Rennes, CHU Rennes, Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail)-UMR S 1085, F-35000 Rennes, France.
INSERM, Centre d'Investigation Clinique 1414, F-35000 Rennes, France.
FHU SUPORT, Rennes, F-35000, France.

Léonard Golbin (L)

FHU SUPORT, Rennes, F-35000, France.
Department of Nephrology, Centre Hospitalier Universitaire de Rennes, F-35000 Rennes, France.

Bénédicte Franck (B)

Univ Rennes, CHU Rennes, Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail)-UMR S 1085, F-35000 Rennes, France.
INSERM, Centre d'Investigation Clinique 1414, F-35000 Rennes, France.
FHU SUPORT, Rennes, F-35000, France.

Pauline Houssel-Debry (P)

Liver Disease Unit, Centre Hospitalier Universitaire de Rennes, F-35000 Rennes, France.

Thierry Frouget (T)

Department of Nephrology, Centre Hospitalier Universitaire de Rennes, F-35000 Rennes, France.

Marie-Pascale Morin (MP)

Department of Nephrology, Centre Hospitalier Universitaire de Rennes, F-35000 Rennes, France.

Henri Brenier (H)

Department of Nephrology, Centre Hospitalier Universitaire de Rennes, F-35000 Rennes, France.

Michel Rayar (M)

Univ Rennes, CHU Rennes, Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail)-UMR S 1085, F-35000 Rennes, France.
INSERM, Centre d'Investigation Clinique 1414, F-35000 Rennes, France.
Liver Disease Unit, Centre Hospitalier Universitaire de Rennes, F-35000 Rennes, France.

Marie-Clémence Verdier (MC)

Univ Rennes, CHU Rennes, Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail)-UMR S 1085, F-35000 Rennes, France.
INSERM, Centre d'Investigation Clinique 1414, F-35000 Rennes, France.
FHU SUPORT, Rennes, F-35000, France.

Cécile Vigneau (C)

Univ Rennes, CHU Rennes, Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail)-UMR S 1085, F-35000 Rennes, France.
FHU SUPORT, Rennes, F-35000, France.
Department of Nephrology, Centre Hospitalier Universitaire de Rennes, F-35000 Rennes, France.

Jonathan Chemouny (J)

Univ Rennes, CHU Rennes, Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail)-UMR S 1085, F-35000 Rennes, France.
INSERM, Centre d'Investigation Clinique 1414, F-35000 Rennes, France.
FHU SUPORT, Rennes, F-35000, France.

Florian Lemaitre (F)

Univ Rennes, CHU Rennes, Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail)-UMR S 1085, F-35000 Rennes, France. florian.lemaitre@chu-rennes.fr.
INSERM, Centre d'Investigation Clinique 1414, F-35000 Rennes, France. florian.lemaitre@chu-rennes.fr.
FHU SUPORT, Rennes, F-35000, France. florian.lemaitre@chu-rennes.fr.
Pharmacology Department, Hôpital Pontchaillou, CHU de Rennes, 2 rue Henri Le Guilloux, 35033 Rennes Cedex, France. florian.lemaitre@chu-rennes.fr.
ORCID: 0000-0002-0908-3629

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Area under the curve of tacrolimus using...
questionsmedicales.fr › Composés chimiques organiques › Lactones › Tacrolimus › Area under the curve of tacrolimus using...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Effets physiologiques des médicaments › Facteurs immunologiques › Immunosuppresseurs › Area under the curve of tacrolimus using...
questionsmedicales.fr › Professions de santé › Médecine › Médecine clinique › Médecine de précision › Area under the curve of tacrolimus using...
questionsmedicales.fr › Procédures de chirurgie opératoire › Transplantation › Transplantation d'organe › Area under the curve of tacrolimus using...
questionsmedicales.fr › Personnes › Receveurs de transplantation › Area under the curve of tacrolimus using...
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Monitorage physiologique › Surveillance des médicaments › Area under the curve of tacrolimus using...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Statistiques comme sujet › Aire sous la courbe › Area under the curve of tacrolimus using...