Analysis of ortho-phthalates and other plasticizers in select organic and conventional foods in the United States.
Alternative plasticizers
DINCH
DINP
Food contact materials
Ortho-phthalates
Plasticizers in food
Journal
Journal of exposure science & environmental epidemiology
ISSN: 1559-064X
Titre abrégé: J Expo Sci Environ Epidemiol
Pays: United States
ID NLM: 101262796
Informations de publication
Date de publication:
09 2023
09 2023
Historique:
received:
30
03
2023
accepted:
15
08
2023
revised:
08
08
2023
medline:
23
10
2023
pubmed:
20
9
2023
entrez:
19
9
2023
Statut:
ppublish
Résumé
ortho-phthalates and other plasticizers impart flexibility to plastics in food production, processing, and packaging; food consumption is a dominant plasticizer exposure pathway. Lower molecular weight ortho-phthalates are being replaced in plastic products due to toxicity concerns, but toxic hazards of and exposures to replacement ortho-phthalates and other plasticizers are poorly understood. We measured 12 ortho-phthalates and 9 other plasticizers in conventional and organic U.S. food products to assess magnitude and profiles of contamination. We measured plasticizers in 34 vegetable oils, 10 milks, 18 infant formulas, and 9 cheese powders from macaroni kits using gas chromatography coupled with mass spectrometry (GC-MS). We analyzed plastic packaging composition using FTIR spectroscopy. We detected eight ortho-phthalates and three alternatives ((1,2-cyclohexane dicarboxylic acid diisononyl ester (DINCH), diethylhexyl terephthalate (DEHT), and diisobutyl adipate (DIBA). Diethylhexyl phthalate (DEHP) was measured in all 71 products. DEHT had the highest concentration of any plasticizer (>10,000 ng/g in three oils). Oils had the highest total plasticizer (median = 770 ng/g, max = 14,900 ng/g) and milk the lowest (median = 88 ng/g, max = 120 ng/g). Organic milk and refined oils had higher median plasticizer levels than conventional. Refined oils had significantly lower concentrations than unrefined oils. Maximum contributors for every category were non-ortho-phthalates: DEHT (powdered infant formula and oils) and DIBA (cheese powder, milk and liquid formula). Plasticizers were not detected in packaging except epoxidized soybean oil in liquid formula lids. Human exposure to plasticizers is a significant public health concern. Nevertheless, sources of such exposures are poorly characterized. This study adds valuable information for estimating legacy and alternative plasticizer exposures from foods. The method developed for measuring DINCH, DINP and DIDP broadens the range of plasticizers other researchers may analyze in future work. The profiles of plasticizer contamination varied depending on the food type. We also document that food processing may be a source of plasticizer contamination in foods.
Sections du résumé
BACKGROUND
ortho-phthalates and other plasticizers impart flexibility to plastics in food production, processing, and packaging; food consumption is a dominant plasticizer exposure pathway. Lower molecular weight ortho-phthalates are being replaced in plastic products due to toxicity concerns, but toxic hazards of and exposures to replacement ortho-phthalates and other plasticizers are poorly understood.
OBJECTIVE
We measured 12 ortho-phthalates and 9 other plasticizers in conventional and organic U.S. food products to assess magnitude and profiles of contamination.
METHODS
We measured plasticizers in 34 vegetable oils, 10 milks, 18 infant formulas, and 9 cheese powders from macaroni kits using gas chromatography coupled with mass spectrometry (GC-MS). We analyzed plastic packaging composition using FTIR spectroscopy.
RESULTS
We detected eight ortho-phthalates and three alternatives ((1,2-cyclohexane dicarboxylic acid diisononyl ester (DINCH), diethylhexyl terephthalate (DEHT), and diisobutyl adipate (DIBA). Diethylhexyl phthalate (DEHP) was measured in all 71 products. DEHT had the highest concentration of any plasticizer (>10,000 ng/g in three oils). Oils had the highest total plasticizer (median = 770 ng/g, max = 14,900 ng/g) and milk the lowest (median = 88 ng/g, max = 120 ng/g). Organic milk and refined oils had higher median plasticizer levels than conventional. Refined oils had significantly lower concentrations than unrefined oils. Maximum contributors for every category were non-ortho-phthalates: DEHT (powdered infant formula and oils) and DIBA (cheese powder, milk and liquid formula). Plasticizers were not detected in packaging except epoxidized soybean oil in liquid formula lids.
IMPACT STATEMENT
Human exposure to plasticizers is a significant public health concern. Nevertheless, sources of such exposures are poorly characterized. This study adds valuable information for estimating legacy and alternative plasticizer exposures from foods. The method developed for measuring DINCH, DINP and DIDP broadens the range of plasticizers other researchers may analyze in future work. The profiles of plasticizer contamination varied depending on the food type. We also document that food processing may be a source of plasticizer contamination in foods.
Identifiants
pubmed: 37726506
doi: 10.1038/s41370-023-00596-0
pii: 10.1038/s41370-023-00596-0
doi:
Substances chimiques
Diethylhexyl Phthalate
C42K0PH13C
Oils
0
phthalic acid
6O7F7IX66E
Phthalic Acids
0
Plasticizers
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
778-786Informations de copyright
© 2023. The Author(s), under exclusive licence to Springer Nature America, Inc.
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