Engineering Cyanobacterial Cell Factories for Photosynthetic Production of Fructose.

Fructose / metabolism Synechococcus / genetics Photosynthesis Metabolic Engineering Carbohydrate Metabolism Sucrose / metabolism Carbon Dioxide / metabolism
cell factories cyanobacteria fructose metabolic engineering

Journal

ACS synthetic biology
ISSN: 2161-5063
Titre abrégé: ACS Synth Biol
Pays: United States
ID NLM: 101575075

Informations de publication

Date de publication:
20 10 2023
Historique:
medline: 23 10 2023
pubmed: 20 9 2023
entrez: 20 9 2023
Statut: ppublish

Résumé

Fructose is an important monosaccharide product widely applied in the food, medicine, and chemical industries. Currently, fructose is mainly manufactured with plant biomass-sourced polysaccharides through multiple steps of digestion, conversion, separation, and purification. The development of cyanobacterial metabolic engineering provides an attractive alternative route for the one-step direct production of fructose utilizing carbon dioxide and solar energy. In this work, we developed a paradigm for engineering cyanobacterial chassis cells into efficient cell factories for the photosynthetic production of fructose. In a representative cyanobacterial strain,

Identifiants

DOI: 10.1021/acssynbio.3c00338 PMID: 37728873
pubmed: 37728873
doi: 10.1021/acssynbio.3c00338
doi:

Substances chimiques

Fructose 30237-26-4
Sucrose 57-50-1
Carbon Dioxide 142M471B3J

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

3008-3019

Auteurs

Jiahui Sun (J)

Shandong Provincial Key Laboratory of Synthetic Biology, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, No. 189 Songling Road, Qingdao 266101, China.
Shandong Energy Institute, No. 189 Songling Road, Qingdao, Shandong 266101, China.
Qingdao New Energy Shandong Laboratory, Qingdao, Shandong 266101, China.
College of Life Science, University of Chinese Academy of Sciences, 100049 Beijing, China.

Zhichao Zhang (Z)

Shandong Provincial Key Laboratory of Synthetic Biology, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, No. 189 Songling Road, Qingdao 266101, China.
Shandong Energy Institute, No. 189 Songling Road, Qingdao, Shandong 266101, China.
Qingdao New Energy Shandong Laboratory, Qingdao, Shandong 266101, China.

Shanshan Zhang (S)

Shandong Provincial Key Laboratory of Synthetic Biology, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, No. 189 Songling Road, Qingdao 266101, China.
Shandong Energy Institute, No. 189 Songling Road, Qingdao, Shandong 266101, China.
Qingdao New Energy Shandong Laboratory, Qingdao, Shandong 266101, China.
College of Life Science, University of Chinese Academy of Sciences, 100049 Beijing, China.

Yu Dan (Y)

Shandong Provincial Key Laboratory of Synthetic Biology, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, No. 189 Songling Road, Qingdao 266101, China.
Shandong Energy Institute, No. 189 Songling Road, Qingdao, Shandong 266101, China.
Qingdao New Energy Shandong Laboratory, Qingdao, Shandong 266101, China.

Huili Sun (H)

Shandong Provincial Key Laboratory of Synthetic Biology, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, No. 189 Songling Road, Qingdao 266101, China.
Shandong Energy Institute, No. 189 Songling Road, Qingdao, Shandong 266101, China.
Qingdao New Energy Shandong Laboratory, Qingdao, Shandong 266101, China.
College of Life Science, University of Chinese Academy of Sciences, 100049 Beijing, China.

Yannan Wu (Y)

Shandong Provincial Key Laboratory of Synthetic Biology, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, No. 189 Songling Road, Qingdao 266101, China.
Shandong Energy Institute, No. 189 Songling Road, Qingdao, Shandong 266101, China.
Qingdao New Energy Shandong Laboratory, Qingdao, Shandong 266101, China.

Guodong Luan (G)

Shandong Provincial Key Laboratory of Synthetic Biology, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, No. 189 Songling Road, Qingdao 266101, China.
Shandong Energy Institute, No. 189 Songling Road, Qingdao, Shandong 266101, China.
Qingdao New Energy Shandong Laboratory, Qingdao, Shandong 266101, China.
College of Life Science, University of Chinese Academy of Sciences, 100049 Beijing, China.
Dalian National Laboratory for Clean Energy, Dalian, Liaoning 116023, China.

Xuefeng Lu (X)

Shandong Provincial Key Laboratory of Synthetic Biology, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, No. 189 Songling Road, Qingdao 266101, China.
Shandong Energy Institute, No. 189 Songling Road, Qingdao, Shandong 266101, China.
Qingdao New Energy Shandong Laboratory, Qingdao, Shandong 266101, China.
College of Life Science, University of Chinese Academy of Sciences, 100049 Beijing, China.
Dalian National Laboratory for Clean Energy, Dalian, Liaoning 116023, China.
Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, Qingdao, Shandong 266237, China.
ORCID: 0000-0002-0570-9196

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Classifications MeSH

questionsmedicales.fr › Glucides › Sucres › Oses › Cétoses (sucres) › Fructose › Engineering Cyanobacterial Cell Factories for...
questionsmedicales.fr › Bactéries › Bactéries à Gram négatif › Bactéries à Gram négatif photosynthétiques › Cyanobactéries › Synechococcus › Engineering Cyanobacterial Cell Factories for...
questionsmedicales.fr › Phénomènes physiologiques des plantes › Photosynthèse › Engineering Cyanobacterial Cell Factories for...
questionsmedicales.fr › Technologie, industrie et agriculture › Ingénierie › Bioingénierie › Ingénierie cellulaire › Génie métabolique › Engineering Cyanobacterial Cell Factories for...
questionsmedicales.fr › Métabolisme › Métabolisme glucidique › Engineering Cyanobacterial Cell Factories for...
questionsmedicales.fr › Glucides › Sucres › Diholoside › Saccharose › Engineering Cyanobacterial Cell Factories for...
questionsmedicales.fr › Produits chimiques inorganiques › Composés de l'oxygène › Oxydes › Dioxyde de carbone › Engineering Cyanobacterial Cell Factories for...